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Innovations in Respiratory Care
Our body has two gateways, the nose and the mouth, that are open to enemies. The enemies that may enter are disease germs which include bacteria, viruses and fungi. These germs may cause various infections to the respiratory system and, in some cases, the whole body.
One of the most common infections in the respiratory system is seasonal influenza. According to WHO, influenza occurs globally with an annual attack rate estimated at 5%–10% in adults and 20% – 30% in children. Worldwide, these annual epidemics are estimated to result in about 3 to 5 million cases of severe illness, and about 250,000 to 500,000 deaths. Annual vaccination and anti-influenza drugs are the most important preventive and therapeutic measures, respectively, but their effects are limited due to the change of serotypes and poor applicability to a high-risk patients as well as the appearance of drug resistant strains.
Egg yolk immunoglobulins (IgY) have been used to treat and prevent respiratory tract infections for many years. Recent research works by various scientist groups have shown that IgY protects mice from infection with various influenza serotypes¹,². These research works open the way for using IgY for prevention and treatment of influenza infections in human. In Japan in recent years specific IgY against influenza has been applied to air-filters, facial masks, tablets and sprays to help consumers reduce the risk of getting infected with influenza.
Wallach MG et al. Cross-Protection of Chicken Immunoglobulin Y Antibodies against H5N1 and H1N1 Viruses Passively Administered in Mice. CLINICAL AND VACCINE IMMUNOLOGY, July 2011, p. 1083–1090.
Nguyen HH et al. Prophylactic and Therapeutic Efficacy of Avian Antibodies Against Influenza Virus H5N1 and H1N1 in Mice. PLOS ONE, April 2010, p. 1-14.
Ovalgen® is a natural egg-product containing immunoglobulins (IgY). It is ideally suited for combining with many different products such as health foods, functional foods or cosmetics. Already today, Ovalgen® is being applied by large food and cosmetic manufacturers, who use it to successfully promote their products.
Ovalgen® FL is to provide consumers with additional protection during flu seasons. Ovalgen® FL can be used in tablet, lozenge, gum, candy, drinks or foods which are convenient for commuters to consume while travelling in buses or trains. Such products are also recommended for people visiting hospitals or crowded places and in situations where using a mask is inconvenient.
Ovalgen® FL-based products are now widely used in Asia including Japan, Korea, India and Vietnam.
The pure form of Ovalgen® FL, called Ecologen FL, has been used in air-filters, masks in Japan and Korea for many years.