In 5 broiler performance datasets/trials covering 364 to 2.2 million birds in the UK, France, USA, and Turkey, Ventar D improved final body weight or daily gain while reducing FCR. Specific examples include 2.2 million Ross 308 broilers in France, where FCR improved by 4 points and ADG by 1.7%, 364 Ross 308 broilers in Scotland, where final body weight increased by 134 g and FCR improved by 5 points, and 3,200 Ross 308 broilers in Turkey, where final body weight increased by 160 g and FCR improved by 6 points.

In 5 broiler gut-health challenge trials involving 240 to 1,680 birds in the USA, Japan, Australia, and one report with location not specified, Ventar D reduced lesion or dysbacteriosis parameters while improving performance. In the 880-bird USA trial, NE lesion scores were 44% lower on day 21 and 50% lower on day 35, with 47% lower mortality; in the 450-bird Australian NE challenge, Ventar D improved BWG by 4.6%, improved livability by 15% overall, and significantly improved villus morphometry; in the 1,680-bird dysbacteriosis trial, dysbacteriosis score was reduced by 1.0 point and FCR improved by 2.5 points.

In 5 nursery piglet trials involving 150 to 532 piglets in Germany, the USA, the Philippines, and one trial where location was not stated in the opened report, Ventar D improved weight gain, feed efficiency, livability, or ZnO-comparable outcomes. In Germany, 220 weaned piglets receiving Ventar D were 750 g heavier with a 3-point FCR improvement; in the USA, 532 piglets showed 670 g higher final weight, 2-point better FCR, and 26.47% lower mortality versus negative control; in the Philippines, 360 piglets showed FCR improvements of 13 points at 150 ppm and 20 points at 300 ppm, with no diarrhea-related mortality at 300 ppm.

In 6 poultry reproduction or egg-production trials involving 324 layer breeders, 600 layers, 750 late-lay hens, 880 female plus 112 male Cobb breeders, and 2,160 female plus 216 male Hubbard breeders, reported in India, Czech Republic, and breeder studies where the opened reports did not specify country, Ventar D or Ventar D plus Activo Liquid improved egg/DOC output or egg quality. Effects included 4.3 more hatching eggs and 3.8 more DOC per hen housed in Cobb breeders, 9.4 more hatching eggs and 12 more DOC per hen housed in Hubbard breeders, 1% higher hen-day egg production and 3.5 additional eggs in Indian layers, and 3% higher hen-day egg production with better shell strength/thickness in Czech late-lay hens.

In 5 non-animal or processing studies conducted at the EW Nutrition Innovation Laboratory in Cologne, Germany, in Serbia, or in murine-cell systems, Ventar D showed mechanism-level improvements rather than zootechnical animal performance. The formulation inhibited ESBL-producing E. coli and Salmonella enterica at 2,500 µg/mL, suppressed Salmonella motility at 750 µg/mL, inhibited C. perfringens growth at 1,000 µg/mL while largely sparing Lactobacillus spp., reduced NFκB activity by up to 54% at 200 ppm, and retained 90% phytomolecule recovery after pelleting at both 70°C/45 s and 80°C/90 s.

In 2 non-standard performance/resilience trials, one with 2,250 juvenile shrimp in extensive production and one with 66 Danic sows in Germany, Ventar D improved productivity or stress-related parameters. Shrimp fed 250 g Ventar D/t showed 2.8 percentage points higher livability, 3% higher biomass per hectare, and 2.6% better FCR over 60 days; supplemented sows showed lower farrowing-related stress indicators, including a significantly reduced salivary cortisol level, relatively lower farrowing duration, and numerically higher body weight at weaning.