Climate across the globe has changed, with rising atmospheric temperatures and carbon dioxide levels. This change favors the growth of toxigenic fungi in crops and thus increases the risk of mycotoxin contamination. When contaminating feed, mycotoxins exert adverse effects in animals and could be transferred into products such as milk and eggs.
95% of the samples were contaminated with at least one mycotoxin
EW Nutrition constantly analyzes feed and raw material samples for their mycotoxin contamination. We report challenges from the most common mycotoxins hindering animal health around the globe.
Worldwide, more than 4,000 analyses on more than 1,000 samples were performed between June – October of the present year. The samples covered grain and by-products commonly used in animal feed worldwide. Figure 1 shows the percentage of the samples tested for which a positive result was found, detailing the number of mycotoxins per sample.
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The number of mycotoxins analyzed per sample can vary based on regional risk-evaluation, including weather conditions, raw material origin and past frequency of positives. However, a minimum number of samples per region is always analyzed for the full spectrum, in order to monitor and corroborate the risk level.
3 or more mycotoxins per sample
95% of the samples were contaminated with at least one mycotoxin. In Europe and Latin America, most samples were analyzed for up to five mycotoxins, and were found contaminated with at least two. In South Asia, three mycotoxins were regularly analyzed per sample and most samples were positive for two. Worldwide, it is common to find samples with 3 or more mycotoxins, indicating that, even in raw materials, poly-contamination is the rule.
Aflatoxin: Main concern for South Asia
From all samples tested positively for mycotoxin contamination, 55% were contaminated with Aflatoxins. In all regions, the maximum levels lay over the thresholds for dairy and poultry. In Europe, less than 20% of the samples were contaminated with Aflatoxin. In Europe and the USA, the average contamination is low, hence this toxin can hardly be considered an issue for animal production in those areas (Figure 2).
In South Asia, where high temperatures and humidity are prevalent, Aflatoxin was detected in more than 95% of the samples and the average contamination is over all thresholds. Management strategies, such as the use of mold inhibitors for stored grain and toxin binders in feed, are necessary in this area to keep animals healthy and productive.
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Impact
Aflatoxins have a negative impact on animal performance, as they affect the function of liver and kidney, alter the immune function, and impair protein synthesis. This affects weight gain, feed efficiency and mortality. Carryover into milk, eggs and edible organs is possible with high or chronic intake of the toxin.
Fumonisins: Main concern for LATAM, also global
Fumonisin was found in 70% of the samples globally and roughly in 90% of the samples coming from Latin America (figure 3). Moreover, in LATAM, more than 50% of the results have values over the threshold for dairy and swine, and 14% over the threshold for poultry, making it a great concern in the area. South Asia is the second concern area, with a high proportion of contaminated samples (80%) and 14% of them representing a danger for poultry production.
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Impact
The main issue with the typical contamination levels of fumonisins – often considered of low risk – is their capacity to disrupt gut health. As their absorption is low, fumonisins interact with other toxins and the gut barrier components, including those affecting immunity and the microbiome. They are known to decrease the available surface for nutrient digestion and absorption, and to increase the risk and incidence of gut-related diseases. As a result, lower productivity is expected in animals exposed to even low levels of this toxin.
Deoxynivalenol (DON): Present worldwide
All across the regions, the maximum tested levels lay over the threshold for dairy, poultry, and swine. This trichothecene was found in more than 70% of the samples analyzed worldwide. In the United States, more than 75% of the positive tested samples showed a contamination with DON and the average of the positives exceeded the thresholds for swine and poultry.
The region with highest maximum values is LATAM, followed by South Asia, and the region with the highest frequency of positives in analyzed samples is Europe. Thus, it can be concluded that the worldwide frequency and levels in which DON is found represent a high risk for production animals.
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Impact
Deoxynivalenol shows a broad spectrum of toxic effects in animals. In poultry and swine, for instance, this mycotoxin is related to lesions in the gastrointestinal tract and alterations in the immune response. This, in turn, leads to lower productivity and poor feed efficiency. DON also interacts with the microbiome, and it is known that it favors the colonization of coliform bacteria in pigs.
Ruminants can tolerate 10–20 times more DON than, for example, pigs. The majority of ingested DON is converted into the less toxic de-epoxy DON, but the degradation rate is influenced by different factors such as the diet, where high starch decrease the process. Moreover, DON also has a detrimental effect on rumen microorganisms, impacting its fermentative capacity.
T2: A danger for poultry producers word-wide
Average levels of T2 were over the threshold for poultry in all regions, with a high presence (>70% of the analyzed samples) in Europe, the US & LATAM.
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Impact
T-2 s is a potent inhibitor of protein synthesis, which affects actively dividing cells, such as the lining of the gastrointestinal tract, skin, and immune cells. The consequences include weight loss or poor weight gain, diarrhea, skin and beak lesions, and decreased production.
T-2 is de-epoxidated in the rumen to HT-2 and neosolaniol, which are significantly less toxic than the parent toxin. In acidotic animals, rumen detoxification of T-2 toxin is impaired and animals may show gastroenteritis and intestinal hemorrhages.
Zearalenone: 80% positive tests globally
More than 80% of all samples tested for this mycotoxin were found positive. The maximum contaminations lay over the thresholds for dairy and swine. These high levels found should not be ignored, considering feedstuffs for long living and reproduction animals.
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Impact
Especially in pig breeding, Zearalenone is an important issue, due to its high absorption and rapid biotransformation into more estrogenic components. Its structural similarity with 17β-estradiol leads this toxin to impair reproductive performance in cows and sows.
Recent studies point to interactions of Zearalenone with immune cells and organs in animals, leading to alterations in cell viability, proliferation, and functionality. Consequences are alterations of the immune response, enhancing the effects of other challenges.
A bad year for crops could be a bad year for production animals
The high mycotoxin contamination found so far in 2021 is partially explained by climate events, such as high temperature and humidity. Temperate zones such as Europe or parts of the USA tend to have higher contaminations compared with previous years.
Multiple mycotoxins co-occur, increasing their impact on animals. Certain combinations of mycotoxins are known to have synergistic or additive effects, aggravating their adverse effects.
To safeguard animal performance, it is important to continually strive for low levels of contamination and to manage the risk of mycotoxins through the use effective tools to measure, interpret, and manage the risk. MasterRisk can aid in the interpretation of mycotoxin risks, weighing in the animal species, age, purpose, as well as the mycotoxin exposure and interactions.
The 3 critical factors for successful pigmentation
By Predrag Persak, Regional Technical Manager, EW Nutrition
We eat with our eyes. Depending on our cultural background and our experience, we prefer foods that have a certain appearance. Moreover, we regulate our taste and health expectations based on this appearance. In that equation, color plays an essential role. Think of healthy-looking salad, fruit, eggs, meat, and more. Certain foods are more appetizing and appear healthier – and, in many cases, are indeed so – when they display a certain color.
For poultry producers, skin color and the yolk color of table eggs are of major concern. This concern is driven by the market (in certain regions, skin and yolk pigmentation heavily affect buying preferences), by regulations, and by an interest in using all options to increase product quality with natural solutions.
Where does poultry pigmentation come from?
Birds cannot synthesize pigments; they must take them up with their feed. Natural pigments have, besides their pigmenting properties, an antioxidant role in the bird’s organism. Unfavorable conditions can heavily influence the outcome of pigmentation. For producers looking to achieve reliable and consistent coloration, results are often unpredictable and disappointing.
Knowing the factors that affect pigmentation will help us to better understand how to achieve the desired level of pigmentation – or to identify, in hindsight what went wrong and when. In general, three different factors are decisive for efficient pigmentation:
The quality of the product (type, content, and stability of the pigment)
The amount of pigment ingested/absorbed/deposited
The persistence of the pigment in the final product
1. Product quality is essential
The first point to be considered is the quality of the product you use, including type, content, and stability of the pigment in the product and the feed.
Content and quality of active substances determine efficacy
Concerning type and content, what matters more than the total amount of carotenoids is the level of active substances. The trans-isomers have higher efficiency than the cis-isomers and are decisive for pigmentation.
Natural pigments originate from natural sources that often vary due to growth conditions, harvest, and handling. Therefore, producers need to control incoming materials and conduct proper formulation during the production process. This is crucial in order to obtain an adequate level of pigments for appropriate pigmentation.
Adequate measures ensure the stability of the pigment in the product
Natural pigments are sensitive to light and air; they are easily oxidized. Also in the feed formulation there are many substances (e.g. oxidized forms of trace elements, choline, chloride) enhancing the oxidation of the pigments. Some precautions can be taken to protect natural pigments from oxidation:
Use of adequate package materials preventing the exposure to light and air
Use of antioxidants in the product as well as in the feed formulation
With these measures in place, the pigments are given adequate protection to ensure their stability.
2. Pigment intake, absorption, and deposition affect pigmentation
Every factor reducing the amount of pigment reaching its target deteriorates the quality of pigmentation. Below are the crucial factors producers need to take into account.
Feed intake is correlated to pigment intake
Assuming that the pigment is homogeneously distributed in the feed, feed intake directly determines the intake of pigment. Consequently, anything that affects feed intake also affects pigment intake and pigmentation. To that end, what is also decisive is particle size and homogeneous distribution of the pigment in the product.
The energy concentration in the feed is also a critical factor. Antinutrients, unpleasant taste, or inconsistent feed structure negatively influence feed intake.
Feed intake is also influenced by other elements:
the animal’s health status
environmental conditions
the availability of water
the housing system (free-range, farm)
feeding management factors (length of the feeding lines, separation of the feed in silo bins or through the feeding lines etc.).
Saponification plays a role in pigment absorption
Through saponification, the natural, esterified form of the pigment gets broken down and the pigment is separated from the fatty acid molecule. This step is necessary to enable the pigment to pass the intestinal wall. The higher the saponification, the better the bioavailability of the pigment.
Besides improving bioavailability, saponification also influences the particle size and the homogeneous distribution of the pigment particles in the product.
Some feed materials and nutrients influence pigment absorption
If pigments are used, it is essential to know that some feed materials or nutrients have a beneficial or adverse effect on the absorption or deposition of the pigments. The inclusion of saturated, low-digestible fats or fat sources decreases pigment absorption and, therefore, the efficacy of pigmentation, whereas unsaturated fats (oils) facilitate it. The addition of oil up to 5% linearly increases pigment deposition in the egg.
Nutrients such as Calcium or Vitamin A also change pigment absorption. In the case of calcium, the level and the source are decisive. High levels of fast soluble limestone or calcium levels higher than 4 % will decrease the absorption. Also, increased levels of Vitamin A are critical for the effectiveness of deposition, as Vitamin A and the pigment use the same transporters. This fact is very important in broilers if vitamin A addition is applied through the water.
Mycotoxins affect feed intake and absorption
The presence of mycotoxins in feed, especially DON, will reduce feed intake due to the bad taste. The gut health-impacting effect of the mycotoxins will increase the passage rate of the feed and will prevent adequate absorption through the intestinal wall. Additionally, the liver function is negatively impacted by the mycotoxins. This results in an affected serum transport and a lower storage capacity for the pigments, leading to lower deposition in the tissue.
Impacted gut health is bad for pigmentation, too
Good gut health is essential for good pigmentation, including the uptake/absorption of pigments, their deposition, but also already existing pigmentation. All health challenges that negatively affect digestion and absorption, such as dysbiosis, negatively influence pigment availability and pigmentation. In such cases, products or strategies improving digestibility and gut integrity can be a solution.
Specific diseases such as NCD, Coryza, helminthiasis, as well as coccidiosis are an important consideration. The first three diseases lower pigment deposition; coccidiosis, however, has multiple impacts. It not only affects digestion and absorption and, therefore, the ongoing pigmentation but also decreases the already existing one.
Coccidia cause damage to the intestinal wall and affect its activity, resulting in a lower absorption. Additionally, the animals lose weight due to an insufficient supply of energy. The consequence is a degradation of fat tissue where the pigments are stored. Furthermore, coccidiosis means oxidative stress for the animal – triggering a reaction of the organism. As pigments also serve as antioxidants, they are removed from the fatty tissues and used as antioxidants.
Within three days post-infection, pigment levels in the subcutaneous tissues, but also in the serum and the liver, drop to 0. Coccidiosis outbreaks occur more frequently in alternative housing systems, affecting broilers, but also laying hens. Paying close attention to coccidiosis and having a proper anticoccidial program in place is obligatory for good pigmentation.
3. Pigmentation ends when the final products are on the shelf
For the end consumer, an attractive color in the final products (such as pasta or the broiler carcass) is essential. Producers of these final products request to put more pigments into the feed, but is this always the solution? As described before, there are a lot of factors possibly impacting the process of pigmentation during animal production on the farm.
However, also in the pasta factory or in the slaughterhouse, pigmentation of the final products can be impacted. In the pasta factory, oxidizing enzymes can destroy the pigments making the pasta pale and unattractive. If they have issues with Salmonella in the slaughterhouse, the birds may be scalded in slightly hotter water. The defeathering afterward can cause the loss of the upper layer of the skin with the pigments.
These examples show why pigmentation is not just the responsibility of the animal producer, but rather continues up to the moment when the pasta or meat is ready for the consumer.
Control these 3 factors for best pigmentation results
Pigmentation is a dynamic process that requires knowledge and attention. The better we control the influences, the more consistent and predictable the outcome. To that end, it is essential to use the product with the best quality, the best amount of pigment that can be not just ingested, but also absorbed and deposited, and with the best persistence in the final product and along its shelf life.
Keeping everything under control is not always possible or is extremely difficult. That is why choosing the right product is a vital link that will allow us to pay more attention to those things that we can find difficult to manage.
To meet all these demands, Colortek Yellow B is the best natural yellow pigment on the market. This highly concentrated natural yellow evidences optimal flowability, homogeneous mixing in feed and high stabilit, for reliable and consistent results. In addition, it boasts high bioavailability and is produced in the EU in a state-of-the art facility, with FAMI-QS certification and strict control of undesirable substances.
Reducing apo-esters: What are the alternatives?
By Technical Team, EW Nutrition
A year ago, the European Commission announced regulation (EU) 2020/1400 – restricting the use of ethyl ester of β-apo-8’-carotenoic acid (generally known as ‘apo-ester’). Starting on 26 October 2021, this legislation restricts the use of apo-ester in poultry feed to 5 mg/kg for laying hens and 15 mg/kg for broilers.
As apo-esters is a synthetic pigment – not naturally occurring in nature – this measure was taken because the authorities could not guarantee safety upon exposure to the user. Limiting the concentration in feed would reduce this risk to acceptable levels, according to the legislators’ decision.
Why use apo-esters in the first place?
Apo-ester is a synthetic yellow colorant, with good stability in premixtures and complete feed. It also has a high deposition rate in the yolk, making it an effective egg yolk colorant.
Its ability to be applied through premix facilitates the proper dispersion in the final feed, which is relevant if micro-dosing systems are lacking in the feed mill.
Why was the legislative change necessary?
The legislative change which limits the use of synthetic apo-ester is based on the precautionary principle and in line with a broader market trend: away from synthetic (non-natural) components, towards the use of naturally occurring alternatives.
The alternative to apo-ester
Natural yellow pigments, typically based on lutein and zeaxanthin produced from marigold oleoresin, are available in the market and can be used to reach the egg yolk pigmentation desired by the consumer. In contrast to apo-ester, these natural solutions are functional antioxidants, further contributing to the egg’s nutritious composition.
Challenges for natural alternatives
However, stability in premixtures and complete feed can be a challenge, with inconsistent yolk coloration as a risk. Safety can also be an issue, so it is important to ask for Quality Control measures routinely applied to avoid contamination with undesired substances (e.g., dioxins). To limit the risk of producing eggs with insufficient yolk coloration, it is important to select natural pigments with excellent stability and deposition efficiency.
What is the best natural alternative to apo-ester?
EW Nutrition’s natural pigment Colortek® Yellow B, produced with a proprietary technology, withstands the harsh conditions in premixtures, while the unique saponification process provides unparalleled deposition rates.
Moreover, Colortek® Yellow B is the most concentrated natural pigment on the market, making it the perfect premix-delivered colorant in the egg industry. If you want to produce all-natural eggs without worrying about the stability of the product or the reliability of your egg coloration, please contact your local EW Nutrition person.
Encapsulation: How a modern phytogenic feed additive makes all the difference
By Technical Team, EW Nutrition
Secondary plant extracts have been shown to improve digestion, have positive effects on intestinal health, and offer protection against oxidative stress in various scientific studies in recent years. Their use as a feed additive has become established and various mixtures, adapted to the various objectives, are widely available.
However, their use in pelleted feed has been criticized for some time. In particular, an unsatisfactory reproducibility of the positive influences on performance parameters is the focus of criticism. The causes invoked for the loss of quantifiable benefits are inadequately standardized raw materials, as well as uncontrollable and uneven losses of the valuable phytomolecules contained during compound feed production.
Delivery mechanisms influence product benefits
The animal production industry has long attempted to reduce its need for antibiotic drugs to an indispensable minimum. As a result, more natural and nature-identical feed additives have been used for preventive health maintenance. These categories include numerous substances that are known in human nutrition in the field of aromatic plants and herbs, or in traditional medicine as medicinal herbs.
The first available products of these phytogenic additives were simply added to compound feed. The desired parts of the plant were, like spices and herbs in human nutrition, crushed or ground into the premix. Alternatively, liquid plant extracts were placed on a suitable carrier (e.g. diatomaceous earth) beforehand in order to then incorporate them into the premix. These procedures are usually less than precise and may be responsible for the difficult reproducibility of positive results mentioned at the beginning.
Another negative factor that should not be underestimated is the varying concentration and composition of the active substances in the plant. This composition is essentially dependent on the site conditions, such as weather, soil, community and harvest time [Ehrlinger, 2007]. In an oil obtained from thyme, the content of the relevant phenol thymol can therefore vary between 30% and 70% [Lindner, 1987]. These extreme fluctuations are avoided with modern phytogenic additives through the use of nature-identical ingredients.
Effective encapsulation is key to stability
The loss of valuable phytomolecules under discussion can also be traced back to the natural origin of the raw materials. Some phytomolecules (e.g. cineole) are volatile even at low temperatures. In regular medicinal use, this effect is mainly employed with cold products. Thus essential oils, such as of mint and eucalyptus, can be added to hot water and inhaled via the resultant steam.
In the process of pelleting in compound feed production, temperatures between 60°C and 90°C are common, depending on the type of production. The process can last for several minutes until the cooling process is over. Sensitive additives can be easily inactivated or volatilized during this step.
A technical solution for the preservation of temperature-sensitive additives is using a protective cover. This is, for instance, an already established practice for enzymes. Such so-called encapsulation is already used successfully in high-quality products with phytogenic additives. The volatile substances should be protected by a coating with fat or starch so that the majority (>70%) of the ingredients can also be found after pelleting.
Unfortunately, complete protection is not possible with this capsule, as this simple protective cover can be broken open by mechanical pressure during grinding and pelletizing. New types of microencapsulation further reduce losses. In a sponge-like type of microencapsulation, if a capsule is destroyed, only a small proportion of the chambers filled with volatile phytomolecules are damaged.
High protection and recovery with Ventar D
A new type of encapsulation, developed by EW Nutrition for use in feed, delivers further optimization. Results show that the technology implemented in Ventar D ensures very high recovery rates of the sensitive phytomolecules even under demanding pelleting conditions.
In a comparative study with encapsulated products established on the market, Ventar D was able to achieve the highest recovery rates in all three tested scenarios (70°C, 45 sec; 80°C, 90 sec; 90°C, 180 sec). In the stress test at a temperature of 90°C for 180 seconds, at least 84% of the valuable phytomolecules were recovered, while the comparison products varied between 70% and 82%. A constant recovery rate of 90% was achieved for Ventar D under simpler conditions.
Phytomolecule recovery rates under processing conditions, relative to mash baseline (100%)
Site-specific release of active ingredients
The major gastrointestinal pathogens (like Clostridia spp., Salmonella spp., E. coli, etc.) are present across the gastrointestinal tract after the proventriculus. This leads to infection or lesions at different sites of preference, reaching up to ceca. Any feed-based solution should have a profound antimicrobial effect. It is, however, also crucial that active ingredients are released across the gastrointestinal tract, for a better contribution to intestinal health.
The unique, innovative delivery system used for Ventar D specifically addresses this point, which many traditional coating technologies do not. Other encapsulation technologies tend to release the active ingredient either too early or too late (depending on the coating composition). The active ingredients in Ventar D reach across sites in the gastrointestinal tract and exert antimicrobial effects, supporting optimal gut health and improving performance.
Economically and ecologically sustainable
In the past, the losses mentioned in compound feed production and especially in pelleting were described as largely unavoidable. To obtain the desired effect of the valuable phytomolecules in the finished product, higher use of products was recommended and thus increased costs to the end-users and the associated CO2 footprint, lowering sustainability overall.
The modern encapsulation technology used in Ventar D now offers significantly better protection for the valuable phytomolecules and, in addition to the economic advantage, also offers more efficient use of the resources required for production.
References
Hashemi, S. R .; Davoodi, H .; 2011; Herbal plants and their derivatives as growth and health promoters in animal nutrition; Vet Res Commun (2011) 35: 169-180; DOI 10.1007 / s11259-010-9458-2; Springer Science + Business Media BV, 2011
Ehrlinger, M., 2007: Phytogenic additives in animal nutrition. Inaugural dissertation. Munich: Veterinary Faculty of the Ludwig Maximilians University in Munich.
Lindner, U., 1987: Aromatic plants – cultivation and use. Contribution to the special show – Medicinal and Spice Plants (Federal Garden Show 1987), Teaching and Research Institute for Horticulture Auweiler-Friesdorf, Düsseldorf.
Water Hygiene: The missing ingredient for successful ABF poultry
By T.J. Gaydos
Water quality is a frequently overlooked part of animal production and it becomes even more important when producing animals in an antibiotic-free (ABF) system. Chickens drink almost twice as much water as they consume feed, and water hygiene is often a second-level priority. Microbes present in water can be primary or secondary pathogens or non-pathogenic. Consuming impure water can add a challenge to the immune system, negatively impacting performance.
Water hygiene is essential for achieving antibiotic-free poultry production
Significant resources are spent on the correct nutrients in the diet and the correct additives for bird health. Water quality should be a priority, and a water quality monitoring program is essential for success in an ABF program. All things being equal, animals will perform better if they have access to high-quality water.
The variability of water quality in the grow-out region should determine how many water quality samples are taken. In highly variable areas, water quality should be measured at every season change on enough farms in every region to know if the solutes are changing. If the water quality is good and consistent, monitoring may be reduced significantly. Water quality should be a part of a “problem farm” work up or related to otherwise unexplained poor performance.
Water-soluble additives: Prevent biofilm
The use of water-soluble products is common in ABF production systems and their frequent use may provide a carbon source for bacteria. This, along with warm temperatures and slow water flow in enclosed water systems, makes the perfect environment for biofilm development.
It is important to frequently flush lines, give birds access to fresh water between additives, and sanitize water lines after using a product that can provide nutrients to bacteria in the line. The biofilm is a perfect location to harbor and protect pathogens from acids and mild or under-dosed disinfectants.
Designing a water quality program
Sample collection
The first step to building a water quality program is to understand the challenge on every farm. Correct sample collection is critical to achieving good results. Take a water sample from as close to the well as possible and submit for water quality analysis: pH, hardness, and minerals. This sample should also be submitted for bacterial load: total aerobic plate count (CFU) per mL and total coliforms per mL.
Monitor bacterial load
A drip sample should be collected from the end of the line for bacterial load analysis as well. This will help determine if the bacterial challenge begins at the source or is limited to the house. Additionally, a swab from the inside of the end of the water line should be taken to determine the level of biofilm. The total bacterial count should be less than 1,000 CFU/mL without fecal coliforms in a free-flowing sample, and total bacteria should be less than 10,000 CFU/mL on a biofilm swab.
Monitor water pH
Water should have a pH between 5 and 8. Water with a pH consistently lower than 5 can be damaging to equipment, while a pH over 8 reduces the efficacy of many disinfectants and can have a bitter taste to birds. Hard water can increase scaling of lines and equipment, leading to leaking seals. Scale also provides a matrix for biofilm formation, making cleaning and disinfection more difficult.
Clean and disinfect water lines
Cleaning water lines between flocks is the minimum program for ABF production. Stabilized hydrogen peroxide products are excellent for disinfecting water lines between flocks. The levels needed for proper disinfection of lines are generally too strong for birds, and the lines must be flushed prior to bird placement.
Water lines are often only cleaned in the house; it is important to periodically clean the lines that transport water from the well or water source to the poultry house as this may be a significant reservoir for bacteria. If the well is identified as a source of contamination, it is essential to seek the help of a qualified technician before adding any sanitizing product to a wellhead.
Continuous disinfection
Ideally, water should be continuously disinfected with a product that is approved for poultry consumption. One of the best products for continuous disinfection is chlorine dioxide, which is effective at reducing bacteria and also reducing the concentrations of some mineral components. High levels of iron in the water can create a favorable environment for E. coli and other bacteria such as C. perfringens.
In addition to disinfection, chlorine dioxide is an effective treatment to reduce soluble iron levels. High sodium and chloride levels can lead to flushing and promote the growth of some bacteria. If high levels of sodium and chloride are consistent across a grow-out region, it may be possible to decrease the levels in the feed to reduce flushing. If the levels of sodium and chloride are considerably high, reverse osmosis should be considered to improve water quality.
Bottom line: invest in high-quality water
Another effective product is stabilized hydrogen peroxide at an appropriate residual level for bird consumption. There are other options for water line sanitation that can be explored on a case-by-case basis.
There are excellent online resources [link] for poultry water quality. The important message remains, in any case, that investment in high-quality water is a critical step for success in ABF poultry production.
References
Austin, B.J., J. Payne, S.E. Watkins, M. Daniels, and B.E. Haggard. 2016. How to Collect Your Water Sample and Interpret the Results for the Poultry Analytical Package. Arkansas Water Resources Center, Fayetteville, AR, FS-2017-01: 8 pp.
Scantling, M. and Watkins, S. 2013. Identify Poultry Water System Contamination Challenges. FSA8011. University of Arkansas Division of Agriculture Research and Extension.
Watkins, S. 2008. Water: Identifying and correcting challenges. Avian Advice 10(3):10-15. University of Arkansas Cooperative Extension Service, Fayetteville, AR
Nutrition and feeding in ABF poultry production
By T.J. Gaydos
Management practices and feed additive selection are often discussed when working in antibiotic-free (ABF) poultry production. Nutrition is another critical component of any agricultural animal system. Working with a qualified nutritionist will help ensure that the diet is correctly formulated with high-quality ingredients.
5 nutrition tips for antibiotic-free poultry production
1. Consider feed form and delivery
Feed form and delivery are nearly as important as the nutrient content of the formulation. If feed form or handling is improper and feed separates, is improperly mixed, or oxidized, the birds will not appreciate the effort that went to develop a balanced diet. A durable pellet or crumble is important to allow all birds to have equal access to a nutritionally complete diet with every bite.
Additionally, if the finished feed or individual ingredients are not stored properly, they may not have the same value that is attributed to them in the formulation process. Other than correct nutrient formulation, three parts of the diet that should be considered are feed additives, mycotoxin contamination, and lipid oxidation.
2. Prevent oxidative stress
The impact of oxidative stress on the intestinal mucosa, immune system, and performance is well-documented across species. Oxidized fat sources reduce the available energy, but equally significant to bird health is the reduction in vitamin availability, resulting in increased oxidative stress for the animal. Protecting the sources of fat and the finished feed is important to spare fat-soluble vitamins, specifically vitamin E.
Oxidized fat can also irritate the intestinal mucosa leading to decreased absorption of nutrients. The process of breaking down macromolecules during digestion and converting them to forms useful for further metabolism is a significant contributor to oxidative stress. The immune system is also a great contributor to oxidative stress. Immune cells use reactive oxygen species to kill pathogens that are phagocytosed.
A large portion of the immune system is located in the GI tract in order to protect the animal from pathogens crossing from the gut into the animal. In addition to being a contributor to oxidative stress, the immune system can be negatively impacted by oxidized feed (Liang et al., 2015). The combination of metabolic and immune activity in the intestines puts it at a high risk of damage from oxidative stress. It is vital to protect fat sources with synthetic or natural antioxidants; reducing the incoming stress from oxidized fat should be a priority to improve poultry health.
3. Mitigate mycotoxin risks
Another risk to bird health and mucosal integrity is mycotoxins. Diets containing mycotoxins may damage the mucosa of the GI tract directly or may damage other organs leading to significant health challenges and decreases in performance. Some mycotoxins or compounds created by fungi can disrupt the intestinal microflora by acting on bacterial cells, as many fungal metabolites are antimicrobial.
The best approach to managing mycotoxins is eliminating them from the system by purchasing high-quality grain and storing it appropriately. It is impossible to completely eliminate all risks of receiving ingredients contaminated with mycotoxins. An internal program should be developed to test the incoming ingredients and finished feed regularly for mycotoxins.
Knowing the challenging ingredient sources may help reduce the risk to highly susceptible birds like Breeders or chicks through dilution in formulation or the addition of toxin binders and/or enzymes. Several toxins may be found in a feed stuff and many of the mycotoxins are synergistic in their deleterious effects (Murugesan et al., 2015). Different binders have varying affinity for different mycotoxins; closely examining the product literature can help to choose the correct product to mitigate risk.
4. Choose optimal additives
Choosing the correct feed additive program for intestinal health, food safety, and growth performance depends on the specific challenges in the complex. When selecting a feed additive that is not FDA approved, it is important to base the decision as much as possible on scientific evidence through peer-reviewed research.
In addition to published data, internal testing within the production system is also helpful to ensure the product matches the local challenge. In a market saturated with “natural” products, it is essential to find a supplier that is trustworthy and is engaged in the success of the complex and health of the birds, not only in selling products. A partnership will be much more successful in the long term than only a buy/sell arrangement.
5. Manage expectations
When considering removing antibiotics from a program, the temptation is to expect natural products to completely replace the efficacy of antibiotics. This is an unreasonable expectation. The success of a transition to ABF production relies on modifying management practices as well. The vast majority of program success is related to attention to the details of husbandry, biosecurity, and sanitation. The remaining opportunity to improve health rests on the additive program.
References
Liang, Fangfang, Shouqun Jiang, Yi Mo, Guilian Zhou, and Lin Yang. “Consumption of Oxidized Soybean Oil Increased Intestinal Oxidative Stress and Affected Intestinal Immune Variables in Yellow-Feathered Broilers.” Asian-Australasian Journal of Animal Sciences 28, no. 8 (2015): 1194–1201. https://doi.org/10.5713/ajas.14.0924.
Murugesan, G.R., D.R. Ledoux, K. Naehrer, F. Berthiller, T.J. Applegate, B. Grenier, T.D. Phillips, and G. Schatzmayr. “Prevalence and Effects of Mycotoxins on Poultry Health and Performance, and Recent Development in Mycotoxin Counteracting Strategies.” Poultry Science 94, no. 6 (2015): 1298–1315. https://doi.org/10.3382/ps/pev075.
How animal nutrition can contribute to sustainability
By Dr. Inge Heinzl, Editor, EW Nutrition
Nowadays, the whole world is talking about sustainability. Many efforts aim to maintain our world for future generations, creating a balance between our current needs and those of our children, grandchildren, and great-grandchildren. The right animal nutrition choices play a crucial role in achieving the challenging aim of sustainable animal production.
Animal nutrition solutions can support producers’ sustainability contributions, from animal welfare to antibiotic reduction
Sustainability – an old concept now set out in writing
The idea of sustainability is not new. Already the first humans lived sustainably, taking only as much as they needed and the environment could cope with, using all parts of the animals they killed. The German Hannss Carl von Carlowitz (1645-1714) coined the term sustainability in his oeuvre “Sylvicultura oeconomica” to counter a threatening raw material crisis. Wood was one of the most important raw materials. Besides heating, it was used for shipbuilding and mining. This was the reason that extensive areas in Europe were deforested and became deserted. Observing the impending disaster, von Carlowitz ” (1713) stated that only as many trees should be felled as can grow back through planned reforestation, sowing, and planting.
The Brundtland Report (1987), a document created by the World Commission on Environment and Development, is reckoned to be the starting signal for worldwide discussions about sustainability. In 2015, the result of a meeting of 193 members of the United Nations was the Agenda 2030 with 17 sustainable development goals for a “world we want” that should be achieved by 2030.
Sustainable Development Goals (SDG) of the Agenda 2030, fixed by the UN in 2015
How can the feed sector contribute to sustainability?
The animal nutrition industry’s sustainability efforts play into different SDGs, notably no. 2, zero hunger, no. 3, good health and well-being, no. 12, responsible consumption and production, no. 13, climate action, no. 14, life below water, and no. 15, life on land. In addition to the overarching goal of fostering higher animal welfare (cf. Keeling et al., 2019), the feed sector’s measures center on three areas:
Optimal use of feed resources, which includes optimizing feed conversion, preserving feed quality, and using alternative ingredients
Preserving the environment by reducing ammonia and methane emissions and energy requirements
Reducing antibiotics usage to maintain their efficacy for future generations
1. Make best use of available resources
One of the 17 points on the list of the United Nations is “responsible consumption and production”. For the feed industry, this means making the most out of available feed sources. Improvements in feed conversion, the maintenance of feed quality, and the use of alternative ingredients are all part of this.
Optimize FCR to utilize the available feed best
The feed conversion rate shows the amount of feed consumed in relation to the outputs produced, such as weight gain, eggs, or milk. The better or lower the feed conversion rate (FCR), the less feed you need to achieve your target, and the higher the yield. Products that improve feed conversion, therefore, can help to save resources.
Good feed conversion or an optimal utilization of nutrients depends on gut health. Only a healthy gut can digest the feed and absorb the nutrients adequately. Hence, products to improve feed conversion often do so by improving gut health.
Phytomolecules: proven to improve feed conversion
Herbs and their active components have been used in human and veterinary medicine for thousands of years to treat digestive tract diseases. Nowadays, products based on phytomolecules help improve feed conversion through their digestive, anti-inflammatory, and antimicrobial effects on the intestinal tract.
How do these three characteristics contribute to a better FCR?
Phytomolecules stimulate the secretion of digestive juices and the motility of the gut
Their antimicrobial effect supports a “healthy” balance in the microbiome, preventing damages of the gut wall by harmful microbes and, therefore, maintaining an optimal nutrient absorption
Their anti-inflammatory properties also contribute to good nutrient absorption and reduce endogenous nutrient loss
FCR improvements in broilers thanks to ACTIVO found in several studies
As phytomolecules are often volatile, EW Nutrition offers encapsulated phytomolecule-based products for the feed (ACTIVO product line). During episodes of elevated enteric challenge, e.g., weaning or following feed change, a liquid solution (ACTIVO LIQUID) can be applied via the waterline.
Enzymes help to make nutrients available
Some feed materials are hard to digest for certain animals. For example, pigs’ digestive systems do not have the enzymes required to break down non-starch polysaccharides (NSPs), such as cellulose, hemicellulose (ß-glucans and xylans), pectins or oligosaccharides. However, pig feed ingredients usually contain these substances.
Besides the non-usability of NSPs, the cage effect is a further problem. Cellulose and hemicellulose, water-insoluble NSPs, encage nutrients such as proteins or digestible carbohydrates. Encaged nutrients cannot be reached by the digestive enzymes and don’t become available to the animal.
Xylanases are available on the market to degrade structural substances in the feed and make them, as well as the nutrients they encaged, available for the organism.
Maintain the quality of your feed materials
Another possibility to save resources is the maintenance of feed quality. Bad weather conditions at harvest or incorrect storage can downgrade feed quality due to the development of molds and their mycotoxins or the oxidation of nutrients. Products mitigating the adverse effects of toxins, acidifiers that reduce microbial load, and antioxidants can help to keep your feed quality on a high level – or to re-establish it.
Mitigate the adverse effects of mycotoxins
Feed materials contaminated with mycotoxins harm animals in different manners and should not be used without further treatment. Mycotoxins are not visible – even if no molds are visible, mycotoxins might be present. Additionally, they are pH- and thermo-stable, meaning that mycotoxins produced in the raw materials on the field remain in the finished feed. As mycotoxins often do not cause apparent, specific symptoms but manifest in decreased performance, feed refusal or lower feed intake, and higher disease susceptibility, it is difficult to notice contamination.
Products such as SOLIS or MASTERSORB contain clay minerals (bentonite and montmorillonite) that adsorb the toxins. MASTERSORB GOLD and MASTERSORB FM also include toxin-adsorbing yeast cell walls and herbal substances to help protect the liver.
Feed spoilage through molds, yeasts, and mycotoxins wastes precious resources
Reduce microbes in the feed with acidifiers
Acidifiers based on organic acids counter harmful microbes in the feed in two ways. Most pathogenic bacteria are susceptible to low pH. The proliferation of, e.g., E. coli, Salmonella, and Clostridium perfringens is minimized at pH < 5 (cf. Fuller 1977). Acidic-tolerant beneficial bacteria such as Lactobacilli or Bifidobacterium, however, survive.
Other than antimicrobial activity, organic acids also cause a significant reduction in ammonia (Eriksen et al., 2014). This finding could be due to a reduction in the microbial deamination of amino acids, which would then be available for absorption, resulting in increased nitrogen digestibility and reduced ammonia excretion, as observed in monogastrics fed organic acids (Pearlin et al., 2020).
The acidifier product lines ACIDOMIX, FORMYCINE, and PRO-STABIL all help protect feed from contamination with pathogenic microorganisms.
Protect the feed’s nutrients from oxidation
The oxidation of nutrients in the feed decreases its nutritional value and, thereby, the value of the whole diet. Fat, proteins, fat-soluble vitamins, pigments, and other biologically active molecules, including sugars and phospholipids, can get oxidized. Metal ions and other pro-oxidative factors can affect the ingredients of the feed during mixing, storage, and feeding. The oxidation of fats and fat-soluble vitamins results in color changes or odors and – this is even more serious – in the production of harmful substances such as aldehydes and ketones. An oxidized feed can lead to oxidative stress in the animals, reduce their immunity, productivity, and livability.
To protect valuable ingredients, the timely addition of effective antioxidants such as STABILON is recommended.
Use alternatives to natural protein sources
Soybeans are an excellent source of protein in animal nutrition. During the last 50 years, soy production has increased from 27 million tons to 269 million tons, causing environmental degradation of forests and savannas (WWF, 2021). The use of alternative protein sources helps protect our environment.
Ruminants partly cover their protein requirements with the help of rumen bacteria. These bacteria can turn nitrogen from urea into bacterial protein, provided they receive enough energy available from carbohydrates. Thanks to its encapsulation, PROTE-N, a feed-grade urea-based nitrogen source, slowly releases nitrogen into the rumen, synchronized with the energy supply. PROTE-N affords producers a degree of independence from soybean protein without compromising nutritional quality.
Reducing soybeans in ruminant feeds helps to lower their environmental impact
2. Preserve the environment
Animal production generates gases such as ammonia and methane that negatively impact the environment. Measures to reduce these gases help to protect plants, animals, us, and our globe.
Reduce ammonia by improving protein digestion
Besides nitrogen oxides, ammonia is one of the primary sources of nitrogen pollution. Ammonia damages ecological systems through acidification and nutritional oversupply. Fast-growing plants that need high amounts of nitrogen or plants that tolerate low soil pH proliferate, whereas more susceptible plants disappear, decreasing biodiversity. According to Max-Planck-Gesellschaft (2017), reducing ammonia emissions by 50 % could prevent 250.000 deaths caused by fine dust worldwide per year.
Improved protein digestion in animals reduces their ammonia production. Decreasing the intestinal pH through using organic acid-based products such as ACIDOMIX or FORMYCINE is essential for the activation and correct functioning of the enzymes responsible for protein digestion.
Reduce methane, the second most abundant greenhouse gas
Together with CO2, N2O, and three fluorinated gases, methane belongs to the greenhouse gases listed in the Kyoto protocol. Being over 25 times more potent than carbon dioxide at trapping heat in the atmosphere, it dramatically affects the earth’s temperature and the climate system (United States Environmental Protection Agency). Methane is a final product of feed fermentation in the rumen and is produced by methanogenic bacteria. Ruminants can produce 250-500 L methane per day (Johnson & Johnson, 1995).
Reducing methane production in ruminants is a critical step towards climate protection. Herbal substances can change the microbiome, leading to improved protein and fiber degradation and reduced methane production (Ku-Vera et al., 2020). ACTIVO PREMIUM is a phytomolecules-based product for ruminants that helps reduce their methane emissions.
Energy savings
To preserve the environment, reducing energy needs is also an important topic. Using the surfactant SURF-ACE in the pelletizing process, feed mills can cut 10-15 % of their energy consumption or produce up to 10-15 % higher pellet output without increasing their energy consumption. When moisture is added together with the surfactant, the emulsion of the dietary fat and the added water leads to better general lubrication of the machinery and improved press throughput.
Feed mill efficiency is key to animal nutrition’s carbon footprint
3. Reduce antibiotic use in animal production to keep this tool effective
Point 3 on the UN’s Agenda 2030 is good health and well-being. For many years, antibiotics, a very effective weapon, have been used to fight bacterial diseases. However, the occurrence of resistance is increasing. One of the reasons is the inappropriate use of antibiotics. These substances are often used preventively or for viral diseases against which they are ineffective. Also, the use of antibiotics as growth promoters at low dosages in animal production strongly contributed to the development of antimicrobial resistance.
Limiting antibiotic use to therapeutic treatment is possible through good farm management and feed supplements that support animals’ gut health, immune systems, and respiratory health. For this purpose, solutions ranging from phytomolecules (ACTIVO products, GRIPPOZON) to egg immunoglobulins (GLOBIGEN products, PROTEGG), products mitigating the impact of toxins (MASTERSORB products, SOLIS), beta-glucans/MOS (BGMOS), and acidifiers (ACIDOMIX, FORMYCINE) are available.
The feed sector has the tools to achieve more sustainability!
The animal nutrition industry provides many products to support animal producers in coping with their main challenges, including the shift to more sustainable production practices. Solutions exist to save feed resources, better protect the environment, and keep antibiotic tools effective. As an additional reward, implementing sustainability solutions leads to healthy animals with high performance. Let’s all help to preserve this planet for our next generations!
References
Eriksen, J., Nørgaard, J. V., Poulsen, H. D., Poulsen, H. V., Jensen, B. B., & Petersen, S. O. (2014). Effects of Acidifying Pig diets on emissions of AMMONIA, methane, and sulfur FROM Slurry during storage. Journal of Environmental Quality, 43(6), 2086–2095. https://doi.org/10.2134/jeq2014.03.0108
Fuller, R. (1977). The importance of lactobacilli in maintaining normal microbial balance in the crop. British Poultry Science, 18(1), 85–94. https://doi.org/10.1080/00071667708416332
Johnson, K. A., & Johnson, D. E. (1995). Methane emissions from cattle. Journal of Animal Science, 73(8), 2483–2492. https://doi.org/10.2527/1995.7382483x
Keeling, Linda, Håkan Tunón, Gabriela Olmos Antillón, Charlotte Berg, Mike Jones, Leopoldo Stuardo, Janice Swanson, Anna Wallenbeck, Christoph Winckler, and Harry Blokhuis. “Animal Welfare and the United Nations Sustainable Development Goals.” Frontiers in Veterinary Science 6 (October 10, 2019). https://doi.org/10.3389/fvets.2019.00336.
Ku-Vera, J. C., Jiménez-Ocampo, R., Valencia-Salazar, S. S., Montoya-Flores, M. D., Molina-Botero, I. C., Arango, J., Gómez-Bravo, C. A., Aguilar-Pérez, C. F., & Solorio-Sánchez, F. J. (2020). Role of secondary plant metabolites on enteric methane mitigation in ruminants. Frontiers in Veterinary Science, 7. https://doi.org/10.3389/fvets.2020.00584
Pearlin, B. V., Muthuvel, S., Govidasamy, P., Villavan, M., Alagawany, M., Ragab Farag, M., Dhama, K., & Gopi, M. (2020). Role of acidifiers in livestock nutrition and health: A review. Journal of Animal Physiology and Animal Nutrition, 104(2), 558–569. https://doi.org/10.1111/jpn.13282
United Nations. (n.d.). How your company can advance each of THE SDGS: UN Global Compact. How Your Company Can Advance Each of the SDGs | UN Global Compact. https://www.unglobalcompact.org/sdgs/17-global-goals.
von Carlowitz, H. C. (1713). Sylvicvltvra oeconomica, oder, Hausswirthliche Nachricht und Naturmässige Anweisung zur Wilden BAŬM-ZŬCHT: Nebst gründlicher darstellung, wie Zu FÖRDERST durch Göttliches Benedeyen Dem allenthalben und insgemein einreissenden Grossen Holtz-mangel: Vermittelst Säe-pflantz- und Versetzung Vielerhand Bäume zu prospiciren …: Worbey zugleich eine Gründliche nachricht von den in Churfl. Sächss. Landen gefundenen Turff Dessen Naturliche beschaffenheit, Grossen NÜTZEN, Gebrauch und nutzlichen verkohlung, Aus Liebe Zu BEFÖRDERUNG des Algemeinen Bestens beschrieben. Verlegts Johann Friedrich Braun.
Want to reduce antibiotic use? Biosecurity and sanitation are crucial
By T.J. Gaydos
Biosecurity may not sound like an exciting topic at first, but it is a critical component of responsible poultry production. It is not enough to devise a strong biosecurity program; that program must also be followed by all people that interact within the system. It only takes one dirty boot or tire to ruin months of hard work.
Achieving good results with a flock largely depends on protecting the birds from biosecurity risks
Antibiotic reduction in poultry requires biosecurity
In a poultry operation, feed, people, and equipment constantly need to go in and out of farms and mills. Thus, no biosecurity program can be perfect. The intensity of the program needs to balance the realities of farming and the current disease pressure. The best program takes all of those into account, additionally considers local weather, availability of supplies, and company/farm staff. It is simple enough to be done even when no one is watching and should be easily scalable in case of increased disease pressure.
The rigorousness of a program must be in due proportion to the local circumstances. Having a biosecurity program that is too strict for the perceived disease pressure may result in people taking the path of least resistance. They probably will not follow instructions, especially if there is not enough monitoring and training to reinforce the value of biosecurity. On the other hand, a program with too lax guidelines will not have the desired effect.
The discrepancy between care requirements and separation
Unfortunately, the most valuable animals in an operation are often the most frequently visited by the most people. Pullets need closely monitored feedings, vaccines, and deworming. Breeders need eggs collected and shipped. Hatcheries require a labor force and maintenance. The feed mill and hatchery are central and overlapping points for all areas of the operation. The human and vehicle traffic at these locations must be closely monitored to reduce the risk of rapid disease transmission.
Feed mills are critical sites for biosecurity measures in poultry production
A physical barrier or sign indicating a biosecurity area on a farm or building entrance can help remind people of the program. Of course, these signs will not stop a disease from entering, nor a person determined to enter a site, but they will cause well-trained people to pause and reflect if they are making a sound decision.
Hygiene is a critical factor
It is well documented that hands and feet are significant transmitters of human and animal pathogens. Several studies have shown that hand washing can reduce absenteeism in school-aged children by 29-57%, thanks to a decrease in gastrointestinal diseases (Wang et al., 2017). Hand washing also reduces the incidence of respiratory illness in human populations by up to 21% (Aiello et al., 2008). Mycoplasmas can survive for one day in a person’s nose, for up to three days in hair, and up to 3-5 days on cotton or feathers (Christensen et al., 1994). Influenza viruses endure 1-2 days on hard surfaces (Bean et al., 1982) and more than a month in pond water (Domanska-Blicharz et al., 2010).
When building a biosecurity program, it is essential to consider the relevant pathogens of concern and the practical ways to reduce their risk of transmission.
How to establish an effective biosecurity program
Generally, biosecurity comprises two important parts:
Physical biosecurity, being the combination of all the physical barriers such as boot washes, signs, and disinfection
Operational biosecurity, covering the processes that protect an operation. This includes downtime, visiting birds in age order, time out for birds from people visiting sick flocks, and respect for physical biosecurity measures. Operational biosecurity starts with training, not only regarding the tasks required to be secure, but also the importance of disease prevention.
Establish several zones
When designing a program, consider four zones of increasing cleanliness: off-farm, on-farm, transition zone, and the animal housing area (Figure 1). Each zone should have a control point to reduce the pathogen load coming in, with exact measures depending on current disease status and bird value. These measures include vehicle sanitation and movement restrictions, footwear cleaning and disinfection, and use of personal protective equipment (PPE).
Figure 1: the four “cleanliness zones” in a farm
Increasing cleanliness from off-farm (red) to on-farm (orange) separated by a physical barrier. The entrance to the facility (transition zone; yellow) and the animal housing area (green).
Cleaning and disinfection are two of the core measures
As hands and feet are the main transmitters of pathogens, washing and sanitizing them is a priority. The outside of the house must be left outside, meaning that hands should be washed frequently and shoes sanitized between sites. Shoe covers should be put on when entering the house.
Cleanliness of the cell phone is often overlooked as a source of disease transmission (Olsen et al., 2020). It is a powerful tool: camera, notebook, light… and notoriously hard to clean. Cleaning and disinfection also apply to all shared tools and equipment that enter farms.
Prevent undesired “cohabitants”
Another critical point in biosecurity is the control of undesired pests and farm animals. Baits must be rotated, available where rodents are frequent, appropriately spaced, and secured from non-target animals. Habitats for pests need to be removed, the perimeter of the buildings must be clear of vegetation and debris, feed and grain spills picked up, and equipment stored away from the facilities. Pets and other farm animals should be kept away from the perimeter of the house and should under no circumstance be allowed to enter the facilities.
Tailored biosecurity programs keep your flock healthy
It is impossible to design a blanket biosecurity program for every operation. Understanding microbiology and disease transmission along with the risk points in a production system will allow a comprehensive plan to be developed. It is important to consider biosecurity as an investment in health and not an optional expense. No program is perfect, but small changes can significantly reduce the risk of pathogens entering the system and leading to major economic and animal welfare issues.
References
Aiello, Allison E., Rebecca M. Coulborn, Vanessa Perez, and Elaine L. Larson. “Effect of Hand Hygiene on Infectious Disease Risk in the Community Setting: A Meta-Analysis.” American Journal of Public Health 98, no. 8 (2008): 1372–81. https://doi.org/10.2105/ajph.2007.124610
Bean, B., B. M. Moore, B. Sterner, L. R. Peterson, D. N. Gerding, and H. H. Balfour. “Survival of Influenza Viruses on Environmental Surfaces.” Journal of Infectious Diseases 146, no. 1 (1982): 47–51. https://doi.org/10.1093/infdis/146.1.47.
Christensen, N. H., Christine A. Yavari, A. J. McBain, and Janet M. Bradbury. “Investigations into the Survival of MYCOPLASMA GALLISEPTICUM, Mycoplasma Synoviae And Mycoplasma Iowae on Materials Found in the Poultry House Environment.” Avian Pathology 23, no. 1 (1994): 127–43. https://doi.org/10.1080/03079459408418980.
Domanska-Blicharz, Katarzyna, Zenon Minta, Krzysztof Smietanka, Sylvie Marché, and Thierry van den Berg. “H5n1 High Pathogenicity Avian Influenza Virus Survival in Different Types of Water.” Avian Diseases 54, no. s1 (2010): 734–37. https://doi.org/10.1637/8786-040109-resnote.1.
Olsen, Matthew, Mariana Campos, Anna Lohning, Peter Jones, John Legget, Alexandra Bannach-Brown, Simon McKirdy, Rashed Alghafri, and Lotti Tajouri. “Mobile Phones Represent a Pathway for Microbial Transmission: A Scoping Review.” Travel Medicine and Infectious Disease 35 (2020): 101704. https://doi.org/10.1016/j.tmaid.2020.101704.
Wang, Zhangqi, Maria Lapinski, Elizabeth Quilliam, Lee-Ann Jaykus, and Angela Fraser. “The Effect of Hand-Hygiene Interventions on Infectious Disease-Associated Absenteeism in Elementary Schools: A Systematic Literature Review.” American Journal of Infection Control, 2017. https://doi.org/10.1016/j.ajic.2017.01.018.
Stop feed spoilage: How organic acids can preserve feed quality
By Technical Team, EW Nutrition
Feed spoilage is a significant issue for the feed industry, leading to loss of nutrients, feed waste, and substantial economic issues for feed and animal producers worldwide (Leyva Salas et al., 2017). Fungal growth is one of the main causes of feed spoilage; it can occur at any stage of the feed production chain, including grain pre- and post-harvest processes, during feed production or storage. Organic acids and their salts are globally used in animal nutrition for microbial preservation and supporting animal health.
Organic acids help preserve animal feed and prevent spoilage through molds, yeasts, and mycotoxins
The threat of molds and yeasts in animal feed
Yeasts and molds can have both positive and negative effects on products consumed by animals and humans. On the one hand, yeasts are used to produce fermented products, such as bread, wine, and beer. On the other hand, yeasts and molds promote the spoilage of raw materials, food, and feeds (Lowes et al., 2000). Molds are among the most potent food and feed spoilers. They can be very resilient to environmental stress, which is a concern in climate change scenarios (Perrone et al., 2020) and enables them to withstand feed preservation measures (Punt et al., 2020).
Several hundred species of molds and yeasts can invade a large variety of raw materials and feeds. They show an easy adaptation to different environments; for instance, they can grow and reproduce in media with pH levels ranging from 2 to above 9 (Tournas et al., 2001). However, the majority of yeasts and molds require free oxygen to grow and thrive.
Excess moisture, high water activity, and high temperatures in feedstuffs are the main mold growth factors that concern the feed industry (Mohapatra et al., 2017). At storage, grains’ moisture content should not exceed 13%, and the water activity of raw materials, feedstuffs, and finished feed should be maintained below 0.8 (Dijksterhuis et al., 2019). Controlling these points contributes to preventing the growth of most pathogens and undesirable microorganisms.
Mold growth reduces the nutritional value of feed, which affects animal health and performance
The microbiology of molds and how they affect the feed
The microbial growth dynamic of grain storage depends on several factors, including the harvest season, grain temperature and moisture content, as well as the type of facility and its environment. For instance, in some areas, grains are harvested at the beginning of the cold season and stored through the following warm season. Storage molds constitute a significant threat to the quality of these raw materials, especially during the warm months, when the stored grains may become hotter than the surrounding environment. This leads to condensation, which increases moisture and water activity. Molds easily thrive in these conditions.
Storage molds reduce the nutritional and commercial value of grains and feeds. For grains, their commercial value decreases when the appearance of kernels changes in a manner recognized by the grain industry as kernel damage. The chemical composition of feeds may deteriorate due to enzymatic actions, resulting in a loss of nutrients (energy, vitamins) and the production of free fatty acids and other unwanted by-products (Reed et al., 2007).
Extensive research has established the factors that influence mold-induced deterioration during grain storage and which management strategies are required:
Moisture content and water activity (a function of the temperature, moisture content, and substrate) – Microorganisms have a limiting water activity below which they cannot grow; therefore, drying the grains below that critical level is part of an effective mold control strategy (Mannaa & Kim, 2017).
Temperature – Grain-contaminating molds thrive in tropical regions, where high temperature and humidity conditions predominate. In general, molds are inactive if the grains are stored below 20 °C (Mousa et al., 2013). However, the temperature of stored grains increases as molds begin to grow in the warmer and/or wetter parts of the grain/feed mass and feed, and heat is generated due to respiration, accelerating the deterioration rate. Moreover, the presence of a temperature gradient in the feedstuffs causes air to move, accelerating the transfer of moisture to cooler grain (Mannaa & Kim, 2017).
Grain quality, including previous storage conditions, insect infestation, presence of broken kernels, and impurities – When grain is too warm, the rate of insects’ breeding is higher (they respond to higher temperatures), the grain contains more humidity and may carry fungal spores. Broken kernels are an easier target for mold and insect infestations than whole ones, increasing the possibility of spoilage (Marcos Valle et al., 2021).
Duration of storage, management, and aeration influence the oxygen and carbon dioxide concentration in the grain mass, which plays a role in mold growth (Marcos Valle et al., 2021).
The consequences of storage deterioration include:
worse organoleptic properties (aspect, texture, taste, and aroma) of grains and feeds
more kernel damage,
higher fat acidity,
slight increase in protein content as non-protein constituents are consumed by mold respiration, causing
Molds and mycotoxins: a toxic relationship for animal health
Beyond their negative impact on feed quality, some fungal genera such as Aspergillus, Penicillium, Alternaria, and Fusarium can produce mycotoxins, secondary metabolites that have toxic effects on humans and animals (Greco et al., 2015). Roughly 60% of raw materials produced for agriculture purposes worldwide are estimated to be contaminated by fungi and mycotoxins (Eskola et al., 2020). Mycotoxins can induce toxic, carcinogenic, and mutagenic reactions even at low concentrations. Their presence in the final feed is a sign of alert as, usually, these metabolites are resistant to technological treatments. Thus, it is important to stop them from entering the feed production chain (Leyva Salas et al., 2017).
Feed-contaminating Fusarium species produce mycotoxins such as trichothecenes, zearalenone, and Fumonisin.
Organic acids: Unrivaled in preventing feed spoilage
It is crucial to reduce the feed losses and improve animal health by controlling fungal contamination at all stages of the feed production chain: from pre-harvest strategies on the field to post-harvest management during storage and even at feed processing. Throughout these processes, producers can apply different management practices. For instance, in field crops, fungal growth can be prevented through crop rotation and tillage; the use of fungicides is a later measure when mold presence exceeds critical levels.
Post-harvest management of grains and their by-products includes drying and storage management through moisture and temperature monitoring and aeration programs. Other spoilage-prevention measures include good hygiene practices and thermal treatments in feed production. However, feed producers and farmers face limitations in applying and linking such measures to tackle the occurrence of these undesirable pathogens (Dijksterhuis et al., 2019).
Pro-Stabil BSL is a product that harnesses the feed preservation effects of organic acids and combines them with surfactants. This means that it can offer a strong yeast and mold inhibition while maintaining the moisture in feed, thus reducing the risk of microbial challenges while prolonging the shelf life of feedstuffs and compound feeds.
Trial results: Pro-Stabil BSL is a great tool to reduce mold growth and manage moisture
Pro-Stabil BSL contains a synergistic blend of organic acids and a surfactant that leads to
» Improved moisture dispersion in the feed
» Increased water retention (reduced water activity)
» Improved anti-mold agent dispersion in the feed and grain
Trial results show a significant decrease in mold growth when Prostabil BSL was added to compound feed. In addition, when moisture was added at 2%, moisture from the environment was also observed, but the mold counts still decreased (Figure 1).
Figure 1: Effects of Pro-Stabil BSL with addition of 2 % moisture on feed quality indicators
When adding Pro-Stabil BSL to animal feed, the following benefits can be expected:
Reduction and prevention of mold growth and recontamination
Improved moisture management
Improved feed mill efficiency production
Improved microbiological quality of grains and feed
Shrinkage management by increasing moisture in feed with no risk of mold development
Reduced water dissipation
Mold growth can lead to sensory defects in feed and reduce its nutritional value. It can also harm animals through the production of mycotoxins. Pro-Stabil BSL offers a safe solution that is also easy to handle. Using the preservative properties of organic acids, Pro-Stabil BSL helps to reduce feed spoilage and its associated effects on animal health and performance.
References
Dijksterhuis, Jan, Martin Meijer, Tineke van Doorn, Jos Houbraken, and Paul Bruinenberg. “The Preservative Propionic Acid Differentially Affects Survival of Conidia and Germ Tubes of Feed Spoilage Fungi.” International Journal of Food Microbiology 306 (2019): 108258. https://doi.org/10.1016/j.ijfoodmicro.2019.108258.
Eskola, Mari, Gregor Kos, Christopher T. Elliott, Jana Hajšlová, Sultan Mayar, and Rudolf Krska. “Worldwide contamination of food-crops with mycotoxins: Validity of the widely cited ‘FAO estimate’ of 25%.” Critical Reviews in Food Science and Nutrition 60, no. 16 (2020): 2773-2789. https://doi.org/10.1080/10408398.2019.1658570
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Harvest to bring significant quality challenges for feed, says EW Nutrition [Press Release]
VISBEK, GERMANY, 23 August – Bad news for feed producers: after supply chain disruptions and raw material unavailability, now weather-related challenges in Europe will most likely affect this year’s crop quantity and quality. Cold temperatures, heatwaves, tornados, and hailstorms are expected to adversely affect the quality and quantity of the harvest.
The moisture brought by the rainfalls is generally expected to affect the quality of the crops. The torrential rains in France, Germany, etc. have darkened Central and Western farmers’ prospects: while the quantity may be there, the quality of wheat and corn is under question. Sprouting grains, diseased crops, and fungi may dampen the optimism brought by numbers alone.
Further east, droughts have posed different issues. Still, countries such as Romania and Bulgaria seem to have weathered the challenges somewhat better and are seeing YoY increases in their wheat and corn crop output.
In Great Britain, rainfall has not caused dramatic drops in crop output but has nevertheless greatly increased mycotoxin risk up to a “moderate to high” level.
Depending on the type of mycotoxin, weather challenges and storage conditions are the most common contributors to severe infestation. This year’s intemperate weather has, in fact, been ideal for a large spectrum of fungi. Fungal risks can be calculated at the two critical times: at flowering and at harvest and baling, when there is an increased risk of storage molds and mycotoxin production.
Preliminary analysis shows Europe’s wheat crops at potential risk of DON, as well as potentially Aflatoxin and Fumonisin infestation and more. Specialists continue to collect and monitor harvest results and adjust recommendations; however, we can definitely expect the presence of moderate, if not quite high levels of mycotoxin risk this year.