{"id":5342,"date":"2018-10-13T02:07:05","date_gmt":"2018-10-13T00:07:05","guid":{"rendered":"https:\/\/ew-nutrition.com\/a-powerful-alternative-to-antibiotics-for-aquaculture\/"},"modified":"2025-01-02T14:40:14","modified_gmt":"2025-01-02T13:40:14","slug":"a-powerful-alternative-to-antibiotics-for-aquaculture","status":"publish","type":"post","link":"https:\/\/ew-nutrition.com\/us\/a-powerful-alternative-to-antibiotics-for-aquaculture\/","title":{"rendered":"A powerful alternative to antibiotics for Aquaculture"},"content":{"rendered":"<div class=\"g-cols wpb_row type_default valign_top vc_inner \">\n<div class=\"vc_col-sm-12 wpb_column vc_column_container\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"wpb_text_column \">\n<div class=\"wpb_wrapper\">\n<p style=\"text-align: justify;\">Global aquaculture has grown dramatically and shrimp cultivation areas, in particular, have expanded. Unfortunately, the shrimp industry, in particular, faces major problems with bacterial diseases. One of the most important diseases in shrimp is vibriosis. Mortality rates of up to 100 % are possible, so economic losses can be devastating.<\/p>\n<p style=\"text-align: justify;\"><strong>Characteristics of vibriosis<br \/>\n<\/strong>Vibriosis generally occurs in all life stages, but mainly in hatcheries. Vibrios are found as normal flora in the hepatopancreas of the healthy crustacean. They can turn from tolerated to pathogenic, if environmental conditions are compromised: e.g. over \/ underfeeding, overcrowding or decreased levels of oxygen.<br \/>\nThe animals can be infected orally, through wounds in the exoskeleton or pores, the gills or the midgut. There are different expressions of the disease depending on which parts of the animal are affected (e.g. appendage and cuticular vibriosis).<\/p>\n<p style=\"text-align: justify;\"><strong>Negative effects on the ecology<br \/>\n<\/strong>As antibiotics for shrimps are applied orally together with the feed, not all of them reach their target. An estimated 15-40 % are not ingested due to feeding falling to the bottom. A fraction of the ingested antibiotics is also not absorbed in the body and is excreted. All of these antibiotics stay in the water or sink to the bottom. The number of antibiotics that remain in the water or sediment varies from 1 % (chloramphenicol) up to 90 % (Oxytetracycline).<br \/>\nIt is estimated that 70-90 % of antibiotics used in the therapy of farmed organisms end up in the environment and sediment and lead to the development of antibiotic resistance.<\/p>\n<p style=\"text-align: justify;\"><strong>Secondary Plant Compounds (SPCs) \u2013 a good tool to reduce the use of antibiotics?<br \/>\n<\/strong>SPCs and their components are able to slow down or prevent the growth of molds, viruses, and bacteria. They impair them by acting at different parts\/mechanisms of the cells (e.g. cell membrane, transport systems, cell contents, flagella development, quorum sensing\u2026). The best-explained mode of action is one of thymol and carvacrol extracted from thyme and oregano. These substances are able to penetrate the bacterial membrane and disrupt its integrity causing loss of ions or energy equivalents.<\/p>\n<p style=\"text-align: justify;\">Several trials conducted show the high efficacy of secondary plant compounds in aquaculture.<\/p>\n<p style=\"text-align: justify;\"><strong>1. Scientific Trial (Kasetsart University, Thailand)<\/strong><\/p>\n<p style=\"text-align: justify;\"><em>Design<\/em><br \/>\na) 4 groups (6 replicates each) of White Leg Shrimp (L. vannamei) were housed in 100 L aquaria with 10 animals each.<\/p>\n<p style=\"text-align: justify;\"><strong>Control:<\/strong> Standard feed, no additive<br \/>\nAB-Group: Standard feed + 10 ppm Enrofloxacin<br \/>\n<strong>Activo Group 1<\/strong>: Standard feed + 100 g Activo\/t of feed<br \/>\n<strong>Activo Group 2:<\/strong> Standard feed + 200 g Activo\/t of feed<\/p>\n<p style=\"text-align: justify;\">Evaluation of mortality and specific growth<\/p>\n<p style=\"text-align: justify;\">a) End of the feeding trial: stressing of the shrimp (high water temperature, 33\u00b0C for 1 hour), then challenge with Vibrio parahaemolyticus (7,6 x 106 cfu\/ml) by subcutaneous injection.<\/p>\n<p style=\"text-align: justify;\">Evaluation of mortality<\/p>\n<p style=\"text-align: justify;\">a) Survival rates in the AB-Group (93,3 %) and in the Activo Group 2 (90,0 %) were similar. The specific growth rate of the AB-Group (2,32 %\/day) and the Activo Group 2 (2,22 %\/day) were higher than the control (1,94 %\/day). The Activo Group 1 (2,18 %\/day) ranged performance-wise between the control and AB-Group.<\/p>\n<p style=\"text-align: justify;\">b) After the challenge, mortality in the control group (43,3%) was approximately twice as high as in the AB-Group (20 %) and in the two Activo groups (both 23,3%).<\/p>\n<p style=\"text-align: justify;\"><strong>2. Field Trial (Shrimp farm Ecuador)<\/strong><\/p>\n<p style=\"text-align: justify;\"><em>Design<br \/>\n<\/em>Two ponds with 80.000 shrimps\/ha<br \/>\n<strong>Control<\/strong> (3 ha): standard feed<br \/>\n<strong>Activo Aqua Group<\/strong> (5 ha): standard feed + 2 kg Activo Aqua (Activo upgraded by immune system stimulating- mannan-oligosaccharides) \/t of feed on top<\/p>\n<p style=\"text-align: justify;\">Evaluation of average shrimp weight at regular intervals<\/p>\n<p style=\"text-align: justify;\"><em>Results<br \/>\n<\/em>Activo Aqua Group showed a consistently better development of body weight compared to the control, resulting in a shorter cultivation period until harvesting (112 compared to 123) and therefore a higher turnover of animals. Feed conversion in the Activo Aqua group was better in every growth stage.<\/p>\n<\/div>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-2777 size-full\" src=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/aqua-data.png\" alt=\"\" width=\"1200\" height=\"300\" srcset=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data.png 1200w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-300x75.png 300w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-1024x256.png 1024w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-500x125.png 500w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-768x192.png 768w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-120x30.png 120w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-40x10.png 40w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-240x60.png 240w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-600x150.png 600w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-160x40.png 160w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-32x8.png 32w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-36x9.png 36w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-150x38.png 150w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-225x56.png 225w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-80x20.png 80w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-48x12.png 48w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-64x16.png 64w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-28x7.png 28w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-920x230.png 920w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-280x70.png 280w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-24x6.png 24w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/\/aqua-data-170x43.png 170w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/><br \/>\n<strong>Both trials present secondary plant compounds as a good alternative to antibiotic growth promoters. In the case of disease, they decrease mortality. Under standard conditions, the improved development shortens time to harvest and increases the turnover. The improved feed conversion lowers feeding costs.<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Global aquaculture has grown dramatically and shrimp cultivation areas, in particular, have expanded. Unfortunately, the shrimp industry, in particular, faces major problems with bacterial diseases. One of the most important diseases in shrimp is vibriosis. Mortality rates of up to 100 % are possible, so economic losses can be devastating. Characteristics of vibriosis Vibriosis generally&#8230;<\/p>\n","protected":false},"author":5,"featured_media":52177,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7996],"tags":[911,7853,1103],"class_list":["post-5342","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-antibiotic-reduction-us-2","tag-secondary-plant-compounds-us","tag-shrimp-nutrition-us","tag-vibriosis-us"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>A powerful alternative to antibiotics for Aquaculture<\/title>\n<meta name=\"description\" content=\"Global aquaculture has grown dramatically and shrimp cultivation areas in particular have expanded. 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