{"id":62141,"date":"2020-12-14T13:28:07","date_gmt":"2020-12-14T12:28:07","guid":{"rendered":"https:\/\/ew-nutrition.com\/?p=62141"},"modified":"2023-03-27T09:05:41","modified_gmt":"2023-03-27T07:05:41","slug":"%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81","status":"publish","type":"post","link":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/","title":{"rendered":"\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981"},"content":{"rendered":"<p><em>by <strong>Inge Heinzl, Marisabel Caballero, Ajay Bhoyar<\/strong>, EW Nutrition<\/em><\/p>\n<p><strong>\u3042\u306a\u305f\u306e\u904b\u55b6<\/strong><strong>\u304b\u3089\u58ca\u6b7b\u6027\u8178\u708e\u3092\u6392\u9664\u3059\u308b\u306b\u306f\u3001\u305d\u308c\u304c\u4f55\u3067\u3042\u308b\u304b\u3001\u4e88\u9632\u65b9\u6cd5\u3001\u304a\u3088\u3073\u5bb6\u79bd\u751f\u7523\u3078\u306e\u5f71\u97ff\u3092\u8efd\u6e1b\u3059\u308b\u65b9\u6cd5\u306b\u3064\u3044\u3066\u5341\u5206\u306b\u7406\u89e3\u3059\u308b\u3053\u3068\u304b\u3089\u59cb\u307e\u308a\u307e\u3059\u3002<\/strong><\/p>\n<p><img decoding=\"async\" class=\"alignnone wp-image-57150\" src=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-300x200.jpg\" alt=\"\" width=\"1200\" height=\"800\" srcset=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-300x200.jpg 300w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-150x100.jpg 150w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-120x80.jpg 120w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-36x24.jpg 36w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-225x150.jpg 225w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-80x53.jpg 80w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-48x32.jpg 48w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-64x43.jpg 64w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-28x19.jpg 28w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/clostridium-perfringens-809x539.jpg 809w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/><\/p>\n<p>\u58ca\u6b7b\u6027\u8178\u708e\u306f\u3001\u5c0f\u8178\u3067<em>Clostridium perfringens<\/em> A\u578b\u304a\u3088\u3073C\u578b\u306e\u904e\u5270\u5897\u6b96\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u5bb6\u79bd\u75be\u60a3\u3067\u3059\u3002<em>C.perfringens<\/em> \u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u6bd2\u7d20\u306f\u3001\u8178\u58c1\u306b\u640d\u50b7\u3092\u4e0e\u3048\u307e\u3059\u3002\u4e00\u822c\u306b\u30012\u301c6\u9031\u9f62\u306e\u30d6\u30ed\u30a4\u30e9\u30fc\u3067\u8d77\u3053\u308a\u307e\u3059\u3002\u7121\u75c7\u72b6\u578b\u3067\u306f\u3001\u6d88\u5316\u7ba1\u306e\u969c\u5bb3\u3092\u7279\u5fb4\u3068\u3057\u307e\u3059\u3002\u81e8\u5e8a\u5f62\u614b\u306f\u3001\u975e\u5e38\u306b\u77ed\u6642\u9593\u3067\u6df1\u523b\u306a\u554f\u984c\u3092\u3082\u305f\u3089\u3057\u3001\u540c\u7fa4\u3067\u306e\u6b7b\u4ea1\u7387\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002<\/p>\n<p>\u58ca\u6b7b\u6027\u8178\u708e\u306f\u3001\u4e16\u754c\u7684\u306a\u5bb6\u79bd\u751f\u7523\u306b\u304a\u3044\u3066\u5e74\u959360\u5104\u30c9\u30eb\u306e\u640d\u5931\u306e\u539f\u56e0\u3067\u3001\u3053\u306e\u75be\u60a3\u306f\u5897\u52a0\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306e1\u3064\u306f\u3001\u52d5\u7269\u751f\u7523\u306b\u304a\u3044\u3066\u6297\u751f\u7269\u8cea\u306e\u81ea\u4e3b\u7684\u307e\u305f\u306f\u6cd5\u7684\u7fa9\u52d9\u306b\u3088\u308b\u524a\u6e1b\u306b\u3088\u308b\u305f\u3081\u3067\u3059\u3002\u3053\u306e\u50be\u5411\u306f\u3001\u6297\u83cc\u5264\u8010\u6027\u306e\u5897\u52a0\u304a\u3088\u3073\u6d88\u8cbb\u8005\u306e\u9700\u8981\u306b\u3088\u3063\u3066\u63a8\u9032\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3082\u3046\u4e00\u3064\u306e\u7406\u7531\u306f\u3001\u30b3\u30af\u30b7\u30b8\u30a2\u306e\u5897\u6b96\u306b\u52a0\u3048\u3066\u3001\u30af\u30ed\u30b9\u30c8\u30ea\u30b8\u30a6\u30e0\u306b\u5bfe\u3057\u3066\u3082\u6709\u52b9\u6027\u3092\u793a\u3059\u30a4\u30aa\u30ce\u30d5\u30a9\u30a2\u306e\u4f7f\u7528\u6e1b\u5c11\u3067\u3059\u3002\u6297\u30b3\u30af\u30b7\u30b8\u30a6\u30e0\u751f\u30ef\u30af\u30c1\u30f3\u3092\u4f7f\u7528\u3059\u308b\u5834\u5408\u3001\u3053\u308c\u3089\u306e\u30a4\u30aa\u30ce\u30d5\u30a9\u30a2\u306e\u4f7f\u7528\u304c\u3067\u304d\u305a\u3001\u30af\u30ed\u30b9\u30c8\u30ea\u30b8\u30a6\u30e0\/\u58ca\u6b7b\u6027\u8178\u708e\u304c\u5897\u52a0\u3057\u307e\u3059 (Williams, 2005)\u3002<\/p>\n<p>\u3053\u308c\u306f\u3059\u3079\u3066\u306e\u5bb6\u79bd\u3067\u5e83\u7bc4\u306a\u554f\u984c\u3067\u3059\u304c\u3001\u7279\u306b\u30d6\u30ed\u30a4\u30e9\u30fc\u306b\u3068\u3063\u3066\u3001\u58ca\u6b7b\u6027\u8178\u708e\u304a\u3088\u3073\u30b3\u30af\u30b7\u30b8\u30a6\u30e0\u75c7\u306f\u6700\u3082\u91cd\u8981\u306a\u5065\u5eb7\u554f\u984c\u3067\u3059\u3002<\/p>\n<h2><strong>\u58ca\u6b7b\u6027\u8178\u708e(NE)\u306e<\/strong><strong>\u75c7\u72b6<\/strong><strong>\u304a\u3088\u3073\u7121<\/strong><strong>\u75c7\u72b6\u75be\u60a3<\/strong><\/h2>\n<h3>\u75c7\u72b6<\/h3>\n<figure id=\"attachment_57184\" aria-describedby=\"caption-attachment-57184\" style=\"width: 300px\" class=\"wp-caption alignright\"><img decoding=\"async\" class=\"wp-image-57184 size-medium\" src=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-300x135.jpg\" alt=\"\" width=\"300\" height=\"135\" srcset=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-300x135.jpg 300w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-150x68.jpg 150w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-120x54.jpg 120w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-36x16.jpg 36w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-225x101.jpg 225w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-80x36.jpg 80w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-48x22.jpg 48w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-64x29.jpg 64w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-28x13.jpg 28w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/necent-chicken-severe-920x415.jpg 920w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-57184\" class=\"wp-caption-text\">(c) Rob Moore<\/figcaption><\/figure>\n<p>\u6025\u6027\u306e\u9ed2\u3063\u307d\u3044\u4e0b\u75e2\u306b\u3088\u3063\u3066\u6fe1\u308c\u305f\u6577\u304d\u85c1\u3092\u767a\u898b\u3057\u3001\u6700\u521d\u306e\u81e8\u5e8a\u5fb4\u5019\u304c\u73fe\u308c\u305f\u5f8c\u3001\u7a81\u71361\u65e5\u3042\u305f\u308a\u6700\u59271\uff05\u306e\u96c6\u56e3\u6b7b\u4ea1\u7387\u306e\u4e0a\u6607\u3092\u7279\u5fb4\u3068\u3057\u307e\u3059\uff08Ducatelle, 2010\uff09\u3002\u6b7b\u4ea1\u7387\u306f\u6642\u300550\uff05\u307e\u3067\u4e0a\u6607\u3057\u307e\u3059\uff08Van der Sluis, 2013\uff09\u3002\u9d8f\u306f\u6c5a\u308c\u305f\u7fbd\u6bdb\u3001\u7121\u6c17\u529b\u3001\u98df\u6b32\u4e0d\u632f\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u5178\u578b\u7684\u306a\u58ca\u6b7b\u306f\u3001\u7c98\u819c\u8868\u9762\u304c\u8352\u308c\u3001\u75c5\u5909\u3001\u304a\u3088\u3073\u8336\u8272\u3063\u307d\u3044\uff08\u30b8\u30d5\u30c6\u30ea\u30a2\u69d8\uff09\u7591\u4f3c\u819c\u3092\u6709\u3059\u308b\u81a8\u3089\u3093\u3060\u5c0f\u8178\u3092\u793a\u3057\u307e\u3059\u3002\u6b7b\u5f8c\u306e\u691c\u67fb\u3067\u306f\u3001\u5927\u91cf\u306e\u6c34\u3063\u307d\u3044\u8336\u8272\u3067\u3001\u8840\u304c\u6df7\u3056\u3063\u305f\u6db2\u4f53\u3067\u3001\u60aa\u81ed\u304c\u3042\u308a\u307e\u3059\u3002\u809d\u81d3\u306f\u9ed2\u304f\u816b\u308c\u3066\u5805\u304f\u306a\u308a\u3001\u80c6\u56a2\u306f\u81a8\u6e80\u3057\u307e\u3059 (Hofacre, 2018)\u3002<\/p>\n<p><strong>\u904e\u6025\u6027<\/strong>\u58ca\u6b7b\u6027\u8178\u708e\u306e\u5834\u5408\u3001\u9d8f\u306f\u521d\u671f\u75c7\u72b6\u3092\u793a\u3055\u305a\u306b\u6b7b\u4ea1\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h3>\u7121\u75c7\u72b6\u75be\u60a3<\/h3>\n<p><img decoding=\"async\" class=\"wp-image-55603 size-medium alignleft\" src=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-300x199.jpg\" alt=\"\" width=\"300\" height=\"199\" srcset=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-300x199.jpg 300w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-150x100.jpg 150w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-120x80.jpg 120w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-36x24.jpg 36w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-600x400.jpg 600w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-225x149.jpg 225w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-80x53.jpg 80w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-48x32.jpg 48w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-64x43.jpg 64w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-28x19.jpg 28w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-812x539.jpg 812w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-280x186.jpg 280w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-500x332.jpg 500w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-24x16.jpg 24w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/polutry-lohmann_imgp1242-170x113.jpg 170w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<p>\u9d8f\u304c\u7121\u75c7\u72b6\u306a\u306e\u306b\u82e6\u3057\u3080\u5834\u5408\u3001\u8178\u7c98\u819c\u306e\u6162\u6027\u7684\u306a\u640d\u50b7\u3068\u5c0f\u8178\u5185\u306e\u7c98\u6db2\u91cf\u306e\u5897\u52a0\u306f\u3001\u6804\u990a\u7d20\u306e\u6d88\u5316\u3068\u5438\u53ce\u306e\u969c\u5bb3\u306b\u3064\u306a\u304c\u308a\u3001\u6210\u9577\u304c\u60aa\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u52a3\u5316\u3057\u305f\u98fc\u6599\u3078\u306e\u5909\u63db\u3068\u305d\u306e\u7d50\u679c\u751f\u3058\u308b\u6210\u9577\u306e\u4f4e\u4e0b\u306f\u300135\u65e5\u9f62\u9803\u306b\u9855\u8457\u306b\u306a\u308a\u307e\u3059\u3002\u98fc\u6599\u304c\u30d6\u30ed\u30a4\u30e9\u30fc\u9d8f\u306e\u751f\u7523\u30b3\u30b9\u30c8\u306e\u7d04 65\uff5e75%\u5bc4\u4e0e\u3059\u308b\u305f\u3081\u3001\u98fc\u6599\u5909\u63db\u304c\u4e0d\u5341\u5206\u3067\u3042\u308b\u3068\u3001\u751f\u7523\u30b3\u30b9\u30c8\u304c\u5897\u52a0\u3057\u3001\u53ce\u76ca\u6027\u306b\u5927\u304d\u304f\u5f71\u97ff\u3057\u307e\u3059\u3002\u3057\u3070\u3057\u3070\u3001\u660e\u78ba\u306a\u75c7\u72b6\u306e\u6b20\u5982\u306e\u305f\u3081\u306b\u3001\u3053\u306e\u7121\u75c7\u72b6\u75be\u60a3\u306f\u672a\u6cbb\u7642\u306e\u307e\u307e\u3067\u3042\u308a\u3001\u751f\u7523\u52b9\u7387\u306b\u6052\u4e45\u7684\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u75c5\u539f\u4f53<\/h2>\n<p><strong>\u58ca\u6b7b\u306e\u539f\u56e0\u306f\u3001\u30b0\u30e9\u30e0\u967d\u6027\u5acc\u6c17\u6027\u7d30\u83cc\u306e<\/strong><strong><em>Clostridium perfringens <\/em><\/strong><strong>A<\/strong><strong>\u578b\u306e\u7279\u5b9a\u306e\u682a\u3068\u3001<\/strong><strong>\u4e00\u90e8\u306e<\/strong><strong>C<\/strong><strong>\u578b\u682a<\/strong><strong>\u3067\u3059<\/strong><strong>\uff08<\/strong><strong>Keyburn, 2008\uff09<\/strong><strong>\u3002<\/strong><\/p>\n<p>\u30af\u30ed\u30b9\u30c8\u30ea\u30b8\u30a6\u30e0\u306f\u3001\u4e3b\u306b\u6709\u6a5f\u7269\u8cea\u304c\u5206\u89e3\u3055\u308c\u308b\u571f\u58cc\u3001\u4e0b\u6c34\u3001\u52d5\u7269\u3084\u30d2\u30c8\u306e\u80c3\u8178\u7ba1\u3067\u5897\u6b96\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u7d30\u83cc\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u6d88\u6bd2\u5264\u3068\u540c\u69d8\u306b\u3001\u74b0\u5883\u3078\u306e\u5f71\u97ff\uff08\u71b1\u3001\u7167\u5c04\u3001\u6392\u9664\uff09\u306b\u3082\u975e\u5e38\u306b\u8010\u6027\u304c\u3042\u308a\u3001\u6570\u5e74\u9593\u751f\u5b58\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u9069\u5207\u306a\u6761\u4ef6\u4e0b\u3067\u306f\u3001<em> C.perfringens<\/em>\u306e\u82bd\u80de\u306f\u98fc\u6599\u3084\u6577\u304d\u85c1\u3067\u5897\u6b96\u3059\u308b\u3053\u3068\u3055\u3048\u3042\u308a\u307e\u3059\u3002<\/p>\n<p><em>C.perfringens<\/em>\u306f\u3001\u9d8f\u306e\u8178\u306e\u5e38\u5728\u83cc\u3067\u3059\u3002\u5065\u5eb7\u306a\u9d8f\u3067\u306f\u3001\u6d88\u5316\u7ba1\u306710<sup>2<\/sup>\uff5e10<sup>4<\/sup> CFU\/g\u3042\u308a\u591a\u7a2e\u591a\u69d8\u306a\u7d30\u83cc\u306e\u6df7\u5408\u7269\u4e2d\u306b\u751f\u5b58\u3057\u3066\u3044\u307e\u3059 (McDevittet, 2006)\u3002\u3053\u306e\u75be\u60a3\u306f\u3001\u901a\u5e38\u3001\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u4f4e\u514d\u75ab\u3001\u304a\u3088\u3073\u8178\u5185\u7d30\u83cc\u53e2\u306e\u4e0d\u5747\u8861\u306a\u3069\u306e\u8981\u56e0\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u308a\u5c0f\u8178\u3067\u6025\u5897\u3057\u305f\u3068\u304d\u306b\u767a\u75c7\u3057\u307e\u3059\u3002\u305d\u306e\u5f8c\u3001\u83cc\u6570\u306f\u6d88\u5316\u7ba1\u306710<sup>7<\/sup>\uff5e10<sup>9<\/sup> CFU\/g\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002\uff08Dahiya, 2005\uff09<\/p>\n<h3>\u58ca\u6b7b\u6027\u8178\u708eB\u6bd2\u7d20(NetB)\uff1b\u58ca\u6b7b\u6027\u8178\u708e(NE)\u306b\u3068\u3063\u3066\u306e\u91cd\u8981\u306a\u75c5\u539f\u6027\u56e0\u5b50<\/h3>\n<p>\u5bbf\u4e3b\u3067\u7acb\u8a3c\u3059\u308b\u305f\u3081\u306b\u3001<em> Clostridium <\/em>\u5c5e\u304a\u3088\u3073\u4ed6\u306e\u75c5\u539f\u4f53\u306f\u3001\u75c5\u539f\u6027\u56e0\u5b50\u306b\u4f9d\u5b58\u3057\u307e\u3059\uff08\u30a4\u30f3\u30d5\u30a9\u30dc\u30c3\u30af\u30b9\u3092\u53c2\u7167\uff09\u3002\u3053\u308c\u3089\u306e\u75c5\u539f\u6027\u56e0\u5b50\u306b\u306f\u3001\u4f8b\u3048\u3070\u3001\u5bbf\u4e3b\u306e\u514d\u75ab\u7cfb\u3078\u306e\u4ed8\u7740\u3001\u56de\u907f\u307e\u305f\u306f\u6291\u5236\u306e\u305f\u3081\u306e\u300c\u624b\u6bb5\u300d\u3001\u6804\u990a\u7d20\u3092\u5f97\u308b\u305f\u3081\u306e\u300c\u624b\u6bb5\u300d\u3001\u8178\u7d30\u80de\u3078\u306e\u4fb5\u5165\u306e\u305f\u3081\u306e\u300c\u624b\u6bb5\u300d\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u9577\u5e74\u306b\u308f\u305f\u308a\u3001<em>C.perfringens<\/em> \u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u03b1\u6bd2\u7d20\u306f\u3001\u3053\u306e\u75be\u60a3\u306e\u767a\u75c7\u304a\u3088\u3073\u4e3b\u8981\u306a\u75c5\u539f\u6027\u56e0\u5b50\u306b\u95a2\u4e0e\u3059\u308b\u3068\u4eee\u5b9a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u30022008\u5e74Keyburn\u306f\u3001\u03b1\u30c8\u30ad\u30b7\u30f3\u3092\u7523\u751f\u3057\u306a\u3044\u304c\u3001\u58ca\u6b7b\u6027\u8178\u708e\u3092\u5f15\u304d\u8d77\u3053\u3059<em> C.perfringens<\/em> \u5909\u7570\u682a\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u5225\u306e\u91cd\u8981\u306a\u75c5\u539f\u6027\u56e0\u5b50\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u305d\u308c\u3067\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306b\u7f79\u60a3\u3057\u3066\u3044\u308b\u9d8f\u306b\u306e\u307f\u5b58\u5728\u3059\u308b\u5225\u306e\u6bd2\u7d20\u304c\u540c\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002<em>C.perfringens<\/em>\u58ca\u6b7b\u6027\u8178\u708eB\u6bd2\u7d20\uff08NetB\uff09\u3067\u3059\u3002NetB\u306f\u5b54\u5f62\u6210\u6bd2\u7d20\u3067\u3059\u3002\u5b54\u5f62\u6210\u6bd2\u7d20\u306f\u3001\u901a\u5e38\u75c5\u539f\u83cc\u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u5916\u6bd2\u7d20\u3067\u3001\u4ed6\u306e\u5fae\u751f\u7269\u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6bd2\u7d20\u306f\u3001\u8178\u58c1\u7d30\u80de\u819c\u306e\u9ad8\u6f54\u3092\u7834\u58ca\u3057\u307e\u3059\u3002\u6f0f\u308c\u305f\u7d30\u80de\u306e\u5185\u5bb9\u7269\u306f\u3001\u7d30\u83cc\u306e\u305f\u3081\u306e\u6804\u990a\u7d20\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u514d\u75ab\u7d30\u80de\u304c\u7834\u58ca\u3055\u308c\u308b\u3068\u3001\u514d\u75ab\u53cd\u5fdc\u304c\u90e8\u5206\u7684\u306b\u5f71\u97ff\u3092\u53d7\u3051\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08Los, 2013\uff09\u3002<\/p>\n<p>\u3055\u3089\u306b\u3001<em>C.perfringens<\/em>\u306e\u75c5\u539f\u6027\u682a\u306f\u30d0\u30af\u30c6\u30ea\u30aa\u30b7\u30f3\u3092\u7523\u751f\u3057\u307e\u3059\u3002\u2014 \u6700\u3082\u91cd\u8981\u306a\u306e\u306fPerfrin\u3067\u3059(Timbermont, 2014)\u3002\u2014 \u7121\u5bb3\u306a<em>Clostridium<\/em>\u5c5e\u306e\u5897\u6b96\u3092\u6291\u5236\u3057\u3001\u9d8f\u306e\u6b63\u5e38\u306a\u8178\u5185\u7d30\u83cc\u53e2\u3092\u7f6e\u304d\u63db\u3048\u307e\u3059 (Riaz, 2017)\u3002<\/p>\n<div style=\"padding: 12px; background-color: #fcf9ed; color: #606060; line-height: 1.4;\">\n<h4><strong>\u75c5\u539f\u6027\u56e0\u5b50\u306e\u4f8b<\/strong><\/h4>\n<p><strong>1.\u63a5\u7740<\/strong><strong>\u56e0\u5b50<\/strong><br \/>\n\u75c5\u539f\u4f53\u304c\u30bf\u30fc\u30b2\u30c3\u30c8\u30db\u30b9\u30c8\u30b5\u30a4\u30c8\u306b\u4ed8\u7740\u307e\u305f\u306f\u4ed8\u7740\u3067\u304d\u308b\u3088\u3046\u306b\u3057\u307e\u3059\uff08\u4f8b\uff1a\u7e4a\u6bdb\uff09\u3002\u7e4a\u6bdb\u306f\u3001\u75c5\u539f\u4f53\u9593\u306eRNA\u307e\u305f\u306fDNA\u306e\u4ea4\u63db\u3092\u53ef\u80fd\u306b\u3057\u307e\u3059\u3002<\/p>\n<p><strong>2.\u4fb5\u5165<\/strong><strong>\u56e0\u5b50<\/strong><br \/>\n\u5bbf\u4e3b\u7d44\u7e54\u5185\u306e\u75c5\u539f\u4f53\u306e\u4fb5\u5165\u304a\u3088\u3073\u5206\u5e03\u3092\u4fc3\u9032\u3059\u308b\uff08\u4fb5\u5165\u3068\u62e1\u6563\u9175\u7d20\uff09\u3002\u4f8b\u3048\u3070\uff1a\u30d2\u30a2\u30eb\u30ed\u30cb\u30c0\u30fc\u30bc\u306f\u3001\u75c5\u539f\u4f53\u304c\u7a4d\u6975\u7684\u306b\u79fb\u52d5\u3059\u308b\u3053\u3068\u3092\u53ef\u80fd\u306b\u3059\u308b\u7d50\u5408\u7d44\u7e54\u307e\u305f\u306f\u97ad\u6bdb\u306e\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u3092\u653b\u6483\u3057\u307e\u3059\u3002<\/p>\n<p><strong>3.\u6bd2\u7d20<\/strong><br \/>\n\u5bbf\u4e3b\u7d30\u80de\u306e\u6a5f\u80fd\u3092\u640d\u50b7\u3059\u308b\u304b\u3001\u305d\u308c\u3089\u3092\u7834\u58ca\u3057\u307e\u3059\uff08\u4f8b\uff1a\u30a8\u30f3\u30c9\u30c8\u30ad\u30b7\u30f3-\u30ea\u30dd\u591a\u7cd6\u985e\u3001\u5916\u6bd2\u7d20\uff09<\/p>\n<p><strong>4.\u56de\u907f\u306e\u6226\u7565<\/strong><br \/>\n\u75c5\u539f\u4f53\u304c\u514d\u75ab\u7cfb\u306e\u9632\u5fa1\u6226\u7565\u3092\u53d7\u3051\u308b\u3053\u3068\u3092\u53ef\u80fd\u306b\u3057\u307e\u3059\uff08\u4f8b\u3048\u3070\u3001\u6297\u98df\u4f5c\u7528\u56e0\u5b50\u306f\u98df\u7d30\u80de\u306b\u3088\u308b\u653b\u6483\u306b\u5bfe\u3059\u308b\u9632\u5fa1\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u7279\u7570\u7684\u6297\u4f53\u306f\u9175\u7d20\u306b\u3088\u3063\u3066\u4e0d\u6d3b\u6027\u5316\u3055\u308c\u307e\u3059\uff09\u3002<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<p><strong>\u6700\u9069\u306a\u5065\u5eb7\u306e\u8178\u3092\u6301\u3064<\/strong>\u9d8f\u306f<strong>\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306e\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u3044<\/strong>\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u6804\u990a\u539f\u3092\u5272\u308a\u5f53\u3066\u3001\u8178\u306e\u74b0\u5883\u3092\u3053\u308c\u3089\u306e\u75c5\u539f\u4f53\u304c\u5897\u6b96\u306b\u9069\u3057\u305f\u3082\u306e\u306b\u3057\u3066\u3082\u3001\u305d\u308c\u3089\u304c\u75c5\u6c17\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u3092\u53ef\u80fd\u306b\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u8ffd\u52a0\u306e<strong>\u8981\u56e0<\/strong>\u304c\u5fc5\u8981\u3067\u3059(Van, 2008; Williams, 2005)\u3002<\/p>\n<h2>\u7d20\u56e0<\/h2>\n<h3>\u98fc\u6599:\u7d44\u6210\u3068\u7c92\u5b50\u30b5\u30a4\u30ba<\/h3>\n<p>\u58ca\u6b7b\u6027\u8178\u708e\u306e\u767a\u75c7\u306b\u304a\u3051\u308b\u98fc\u6599\u306e\u5f79\u5272\u3092\u904e\u5c0f\u8a55\u4fa1\u3057\u3066\u306f\u306a\u308a\u307e\u305b\u3093\u3002\u3053\u308c\u306f\u3001<em> C.perfringens<\/em> \u306b\u6709\u5229\u306a\u8178\u5185\u74b0\u5883\u3092\u4f5c\u6210\u3059\u308b\u7269\u8cea\u304c\u6d3b\u52d5\u306b\u95a2\u4e0e\u3057\u3066\u304f\u308b\u3068\u3053\u308d\u3067\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>NSps<\/strong>\uff08\u975e\u30c7\u30f3\u30d7\u30f3\u591a\u7cd6\u985e\uff09<\/p>\n<p><strong>\u4f5c\u7528\u6a5f\u5e8f<\/strong><\/p>\n<p>-\u7c98\u5ea6\u3092\u4e0a\u3052\u308b<\/p>\n<p>-\u900f\u904e\u7387\u3092\u4e0b\u3052\u308b\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000<em>C.perfringens<\/em>\u304c\u5229\u7528\u3067\u304d\u308b\u591a\u304f\u306e\u6804\u990a\u7d20<\/p>\n<p>-\u4ed6\u306e\u6804\u990a\u7d20\u306e\u6d88\u5316\u7387\u3092\u4e0b\u3052\u308b<\/p>\n<p>-\u6804\u990a\u7d20\u3092\u63d0\u4f9b\u3059\u308b<\/p>\n<p>\u7c98\u6db2\u7523\u751f\u306e\u523a\u6fc0\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u5acc\u6c17\u7684\u74b0\u5883<\/p>\n<p>(Van, 2013\u3001Kaldhusdal, 1996\u3001Annett, 2002)<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u8102\u8cea<\/strong><\/p>\n<p><strong>\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u904e\u5270\u306a\u542b\u6709\u91cf<\/strong><\/p>\n<p><strong>\u96e3\u6d88\u5316\u6027\u30bf\u30f3\u30d1\u30af\u8cea<\/strong><\/p>\n<p>\u9b5a\u7c89\u306e\u3088\u3046\u306a\u7279\u5225\u306a\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u3000\u3000\u3000\u3000\u8178\u5185\u83cc\u5c64\u306e\u30d0\u30e9\u30f3\u30b9\u306e\u5909\u5316<\/p>\n<p>\u4e9c\u925b\/\u30b0\u30ea\u30b7\u30f3\u306e\u6fc3\u5ea6\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000(Antonissen, 2016)<\/p>\n<p><strong>\u4f5c\u7528\u6a5f\u5e8f<\/strong><\/p>\n<p>-\u6d88\u5316\u7ba1\u306b\u304a\u3051\u308b\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30ec\u30d9\u30eb<\/p>\n<p>-\u7d30\u83cc\u306e\u6804\u990a\u7d20\u3068\u3057\u3066\u5229\u7528<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u52d5\u7269\u6027\u8102\u8cea<\/strong><\/p>\n<p><strong>\u4f5c\u7528\u6a5f\u5e8f<\/strong><\/p>\n<p>-\u3000\u9ad8\u3044\uff50H\u3068\u9ad8\u3044\u80c6\u6c41\u5869\u6fc3\u5ea6\u3000\u3000\u3000\u3000\u3000\u3000<em>C.perfringens<\/em>\u306e\u5897\u52a0<\/p>\n<p>-\u3000\u7403\u83cc\u306e\u5897\u6b96\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000(Knarreborg, 2002\uff09<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u7c92\u5f84<\/strong><\/p>\n<p>\u7c92\u5f84\u304c\u5747\u4e00\u3067\u306a\u3044\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000 \u00a0\u3000\u3000\u58ca\u6b7b\u6027\u8178\u708e\u306e\u5897\u52a0\u7387<\/p>\n<p>\uff08Branton, 1987\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>\u7d30\u304f\u7815\u304f<\/p>\n<p><strong>\u4f5c\u7528\u6a5f\u5e8f\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000 \u3000\u3000<\/strong><strong>\u00a0 \u3000<\/strong>\u75c5\u539f\u5fae\u751f\u7269\u306e\u5897\u52a0<\/p>\n<ul>\n<li>\u7802\u56a2\u306e\u7b4b\u8089\u7d44\u7e54\u2193\u3000\u3000\u3000\u3000\u3000\u3000\u3000 \u3000\u3000\uff08Salmonella, Campylobacter, Clostridium\u2026\uff09<\/li>\n<li>\uff50H\u2191\u3001\u6d88\u5316\u7ba1\u901a\u904e\u6642\u9593\u2193\u3000\u3000\u3000\u3000\u3000\u3000\u3000\uff08\u7c97\u3044\u30c8\u30a6\u30e2\u30ed\u30b3\u30b7\u3068\u6bd4\u8f03\u3057\u3066\uff09<\/li>\n<\/ul>\n<p>\uff08Rougiere, 2010; Santos, 2008; Singh, 2014\uff09<\/p>\n<h3><\/h3>\n<h3>\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\u6c5a\u67d3<\/h3>\n<p><strong>\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\u306f\u6d88\u5316\u5668\u5b98\u306b\u5bb3\u3092\u53ca\u307c\u3057\u3001<\/strong><em>C.perfringens<\/em><strong>\u306e\u5897\u6b96\u306b\u7406\u60f3\u7684\u306a\u6761\u4ef6\u3092\u4f5c\u308a\u51fa\u3057\u307e\u3059 <\/strong>\u00a0<strong>\u3002<\/strong><\/p>\n<p>\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\u306f\u3001<em>C.perfringens<\/em>\u5897\u6b96\u3001\u6bd2\u7d20\u7523\u751f\u3001\u307e\u305f\u306fNetB\u7523\u751f\u306b\u76f4\u63a5\u4f5c\u7528\u3057\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\u306f\u6d88\u5316\u5668\u5b98\u3092\u7834\u58ca\u3057\u3001\u75c5\u539f\u4f53\u306b\u3068\u3063\u3066\u597d\u307e\u3057\u3044\u74b0\u5883\u3092\u4f5c\u308a\u51fa\u3057\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u6b21\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<ol>\n<li>\u30c7\u30aa\u30ad\u30b7\u30cb\u30d0\u30ec\u30ce\u30fc\u30eb(DON)\u306f\u3001\u8178\u969c\u58c1\u3092\u7834\u58ca\u3057\u3001\u4e0a\u76ae\u3092\u640d\u50b7\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001<em>C.perfringens<\/em>\u306e\u5897\u6b96\u306e\u305f\u3081\u306e\u826f\u597d\u306a\u6761\u4ef6\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u304a\u305d\u3089\u304f\u7d50\u679c\u3068\u3057\u3066\u751f\u3058\u308b\u4e0a\u76ae\u306e\u900f\u904e\u6027\u304a\u3088\u3073\u98df\u7269\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5438\u53ce\u306e\u4f4e\u4e0b\u306f\u3001\u5c0f\u8178\u306b\u304a\u3051\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5897\u52a0\u3092\u3082\u305f\u3089\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u75c5\u539f\u4f53\u306e\u6804\u990a\u7d20\u3068\u3057\u3066\u5f79\u7acb\u3064\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059 (Antonissen, 2014)\u3002<\/li>\n<li>\u30c7\u30aa\u30ad\u30b7\u30cb\u30d0\u30ec\u30ce\u30fc\u30eb(DON)\u304a\u3088\u3073\u4ed6\u306e\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\u306f\u3001\u4e73\u9178\u7523\u751f\u7d30\u83cc\u306e\u6570\u3092\u6e1b\u5c11\u3055\u305b\u3001\u5fae\u751f\u7269\u30d0\u30e9\u30f3\u30b9\u3092\u5909\u5316\u3055\u305b\u307e\u3059 (Antonissen, 2016)\u3002<\/li>\n<\/ol>\n<h3>\u30a2\u30a4\u30e1\u30ea\u30a2\u5c5e<\/h3>\n<p>\u7121\u50b7\u306e\u8178\u4e0a\u76ae\u306f\u3001<em>C.perfringens<\/em>\u306a\u3069\u306e\u6f5c\u5728\u7684\u306a\u75c5\u539f\u4f53\u306b\u5bfe\u3057\u3066\u6700\u826f\u306e\u9632\u5fa1\u3067\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u30b3\u30af\u30b7\u30b8\u30a6\u30e0\u75c7\u306b\u3064\u3044\u3066\u8aac\u660e\u3057\u307e\u3059\u3002Moore\uff082016\uff09\u306f\u3001\u8178\u4e0a\u76ae\u3092\u640d\u50b7\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30a2\u30a4\u30e1\u30ea\u30a2\u5c5e\u306f\u7c98\u819c\u4e0a\u76ae\u306e\u8178\u57fa\u5e95\u9818\u57df\u3078\u306e\u4fb5\u5165\u3092<em>C.perfringens<\/em>\u306b\u4e0e\u3048\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u5f8c\u3001\u75c5\u7406\u5b66\u7684\u30d7\u30ed\u30bb\u30b9\u306e\u7b2c1\u6bb5\u968e\u304c\u884c\u308f\u308c\u3001\u305d\u3053\u304b\u3089<em>C.perfringens<\/em> \u304c\u56fa\u6709\u5c64\u306b\u4fb5\u5165\u3057\u307e\u3059\u3002\u4e0a\u76ae\u306e\u640d\u50b7\u304c\u7d9a\u304d\u307e\u3059 (Olkowski, 2008)\u3002\u8178\u306b\u6f0f\u308c\u308b\u8840\u6f3f\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u7523\u751f\u3055\u308c\u308b\u7c98\u6db2\u306f\u8c4a\u5bcc\u306a\u6804\u990a\u6e90\u3067\u3059\uff08Van\u30012004; Collier\u30012008\uff09\u3002\u00a0\u30b3\u30af\u30b7\u30b8\u30a6\u30e0\u75c7\u306e\u3055\u3089\u306a\u308b\u5f71\u97ff\u306f\u3001\u751f\u6765\u306e\u514d\u75ab\u9632\u5fa1\u3092\u6d3b\u6027\u5316\u3059\u308b <em>Candidatus savagella<\/em>\u306e\u6570\u3092\u6e1b\u3089\u3059\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u8178\u5185\u306e\u5fae\u751f\u7269\u30d0\u30e9\u30f3\u30b9\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n<p><img decoding=\"async\" class=\"wp-image-57252 aligncenter\" src=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-300x166.jpg\" alt=\"\" width=\"800\" height=\"443\" srcset=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-300x166.jpg 300w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-150x83.jpg 150w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-120x66.jpg 120w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-36x20.jpg 36w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-225x125.jpg 225w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-80x44.jpg 80w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-48x27.jpg 48w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller.jpg 1920w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-64x35.jpg 64w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-28x16.jpg 28w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/villi-eimeria-clostridium-smaller-920x509.jpg 920w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<ol>\n<li><em>\u30a2\u30a4\u30e1\u30ea\u30a2<\/em> \u306f\u4e0a\u76ae\u7d30\u80de\u3092\u6bba\u50b7\u3057\u3066\u8840\u6f3f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6f0f\u51fa\u3092\u8a98\u767a\u3057\u307e\u3059\u3002<\/li>\n<li>\u305d\u308c\u3089\u306f\u8178\u5185\u306e\u7c98\u6db2\u7523\u751f\u3092\u5897\u5f37\u306b\u3057\u307e\u3059\u3002<\/li>\n<\/ol>\n<p>1+2\u306f\u3001\u5229\u7528\u53ef\u80fd\u306a\u6804\u990a\u7d20\u306e\u5897\u52a0\u3092\u3082\u305f\u3089\u3057\u3001<em>C.perfringens<\/em> \u306e\u5897\u6b96\u306b\u6709\u5229\u306a\u74b0\u5883\u3092\u4f5c\u308a\u51fa\u3057\u307e\u3059\u3002<\/p>\n<p><em>\u30a2\u30a4\u30e1\u30ea\u30a2<\/em> \u5c5e\u3060\u3051\u3067\u306a\u304f\u3001\u4ed6\u306e\u75c5\u539f\u4f53\uff08\u4f8b\u3048\u3070<em> \u30b5\u30eb\u30e2\u30cd\u30e9<\/em>\u5c5e\u3001\u30a2\u30b9\u30ab\u30ea\u30c3\u30c9\u5e7c\u866b\u3001\u30a6\u30a4\u30eb\u30b9\uff09\u3084\u8178\u7c98\u819c\u306b\u640d\u50b7\u3092\u4e0e\u3048\u308b\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\u306a\u3069\u306e\u7269\u8cea\u306f\u3001<em>C.perfringens<\/em>\u611f\u67d3\u306e\u305f\u3081\u306e\u9053\u3092\u958b\u304f\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<em>\u30a2\u30a4\u30e1\u30ea\u30a2<\/em>\u5c5e\u306e\u5375\u6bcd\u7d30\u80de\u306e\u767a\u6563\u306b\u4e0d\u53ef\u6b20\u306a\u6e7f\u6c17\u306e\u3088\u3046\u306a\u7d20\u56e0\u3082\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306e\u4fc3\u9032\u56e0\u5b50\u3068\u3057\u3066\u8003\u616e\u3055\u308c\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002(Williams\uff642005\uff09\u3002<\/p>\n<h3>\u514d\u75ab\u6291\u5236\u56e0\u5b50<\/h3>\n<p>\u3059\u3067\u306b\u8aac\u660e\u3055\u308c\u3066\u3044\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b5\u30fc\u98fc\u6599\u3001\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\u304a\u3088\u3073\u30b3\u30af\u30b7\u30b8\u30a2\u306b\u52a0\u3048\u3066\u3001\u4ed6\u306e\u7d20\u56e0\u3082\u8a00\u53ca\u3055\u308c\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u4e00\u822c\u306b\u3001\u52d5\u7269\u306b\u30b9\u30c8\u30ec\u30b9\u3092\u8a98\u767a\u3059\u308b\u8981\u56e0\u306f\u3001\u8178\u5185\u7d30\u83cc\u53e2\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u5d29\u3057\u307e\u3059\u3002\u7d50\u679c\u3068\u3057\u3066\u751f\u3058\u308b\u514d\u75ab\u7cfb\u306e\u6291\u5236\u306f\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306e\u30ea\u30b9\u30af\u306b\u5bc4\u4e0e\u3057\u307e\u3059\uff08Tsiouris, 2016\uff09\u3002\u3053\u308c\u3089\u306e\u8981\u56e0\u306f\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n<p><strong>\u7d30\u83cc<\/strong> :Shivaramiaah(2011)\u306f\u3001\u58ca\u6b7b\u6027\u8178\u708e\u7d20\u56e0\u3068\u3057\u3066\u65b0\u751f\u5150<em>Salmonella typhimurium<\/em>\u611f\u67d3\u3092\u8abf\u67fb\u3057\u307e\u3057\u305f\u3002\u65e9\u671f\u611f\u67d3\u306f\u3001\u8178\u306b\u91cd\u5927\u306a\u640d\u50b7\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059(Porter, 21)\u3002\u3055\u3089\u306b\u3001Hassan(1994) \u306f\u3001<em>S.typhimurium<\/em>\u306e\u611f\u67d3\u304c\u30ea\u30f3\u30d1\u7403\u306e\u767a\u751f\u306b\u60aa\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3001<em>C.perfringens<\/em>\u306e\u30b3\u30ed\u30cb\u30fc\u5f62\u6210\u3092\u4fc3\u9032\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><strong>\u30a6\u30a4\u30eb\u30b9 <\/strong>:\u4f1d\u67d3\u6027\u30d5\u30a1\u30d6\u30ea\u30ad\u30a6\u30b9\u56a2\u75c5(IBD)\u306f\u3001\u30b5\u30eb\u30e2\u30cd\u30e9\u3001\u30d6\u30c9\u30a6\u7403\u83cc\u3060\u3051\u3067\u306a\u304f\u3001\u30af\u30ed\u30b9\u30c8\u30ea\u30b8\u30a6\u30e0\u306b\u3088\u308b\u611f\u67d3\u306e\u91cd\u75c7\u5ea6\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4ed6\u306e\u30af\u30ed\u30b9\u30c8\u30ea\u30b8\u30a6\u30e0\u3092\u4fc3\u9032\u3059\u308b\u30a6\u30a4\u30eb\u30b9\u6027\u75be\u60a3\u3068\u3057\u3066\u306f\u3001\u30ac\u30f3\u30dc\u30ed\u75c5\u3084\u30de\u30ec\u30c3\u30af\u75c5\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p><strong>\u30b9\u30c8\u30ec\u30b9 <\/strong>:\u8178\u7ba1\u306f\u3001\u3042\u3089\u3086\u308b\u30bf\u30a4\u30d7\u306e\u30b9\u30c8\u30ec\u30b9\u306b\u7279\u306b\u654f\u611f\u3067\u3042\u308b\u3002\u3053\u306e\u30b9\u30c8\u30ec\u30b9\u306f\u3001\u9ad8\u6e29\u3001\u9ad8\u5bc6\u5ea6\u3001\u98fc\u6599\u4f9b\u7d66\u306e\u6025\u6fc0\u306a\u5909\u5316\u306a\u3069\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-62143\" src=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-300x192.png\" alt=\"\" width=\"600\" height=\"383\" srcset=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-300x192.png 300w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-150x96.png 150w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-120x77.png 120w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-36x23.png 36w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-225x144.png 225w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-80x51.png 80w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-48x31.png 48w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja.png 1144w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-64x41.png 64w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-28x18.png 28w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/content-images\/stress-factors-ja-844x539.png 844w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>&nbsp;<\/p>\n<h2>\u6cbb\u7642<\/h2>\n<p>\u6025\u6027\u306e\u5834\u5408\u3001\u8fb2\u5bb6\u306f\u7363\u533b\u5e2b\u306b\u76f8\u8ac7\u3057\u3001\u9d8f\u3092\u6cbb\u7642\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u51e6\u7406\u306f\u98fc\u6599\u307e\u305f\u306f\u98f2\u6c34\u3067\u884c\u308f\u308c\u308b\u305f\u3081\u3001\u98f2\u6c34\u307e\u305f\u306f\u98fc\u6599\u3092\u6d88\u8cbb\u3059\u308b\u9d8f\u306e\u307f\u304c\u51e6\u7406\u3055\u308c\u308b\u3053\u3068\u306b\u8a00\u53ca\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h3>\u6297\u751f\u7269\u8cea<\/h3>\n<p>\u30b0\u30e9\u30e0\u967d\u6027\u83cc\u3092\u6a19\u7684\u3068\u3059\u308b\u6297\u751f\u7269\u8cea\u306f\u3001\u6025\u6027\u58ca\u6b7b\u6027\u8178\u708e\u306e\u6cbb\u7642\u306b\u4e00\u822c\u7684\u306b\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u6297\u751f\u7269\u8cea\u306e\u9078\u629e\u306f\u3001\u98fc\u80b2\u69d8\u5f0f\u304a\u3088\u3073\u8fb2\u5834\/\u7fa4\u308c\u306b\u304a\u3051\u308b\u62b5\u6297\u907a\u4f1d\u5b50\u306e\u5b58\u5728\u3092\u8003\u616e\u3057\u3066\u3001\u7363\u533b\u5e2b\u306b\u3088\u3063\u3066\u5bfe\u51e6\u3055\u308c\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u6297\u751f\u7269\u8cea\u306e\u4e88\u9632\u7684\u4f7f\u7528\u306f\u63a8\u5968\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u591a\u304f\u306e\u56fd\u306f\u3059\u3067\u306b<a href=\"https:\/\/ew-nutrition.com\/challenging-times-for-broilers\/\"><strong>\u6297\u83cc\u5264\u8010\u6027<\/strong><\/a>\uff08AMR\uff09\u3092\u4f4e\u6e1b\u3059\u308b\u305f\u3081\u306b\u305d\u308c\u3092\u7981\u6b62\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<div style=\"padding: 12px; background-color: #fcf9ed; color: #606060; line-height: 1.4;\">\n<h4><strong>\u6297\u83cc<\/strong><strong>\u5264<\/strong><strong>\u8010\u6027\uff08AMR\uff09<\/strong><\/h4>\n<p>\u3044\u304f\u3064\u304b\u306e\u7d30\u83cc\u306f\u3001\u907a\u4f1d\u5b50\u5909\u7570\u306e\u305f\u3081\u306b\u7279\u5b9a\u306e\u6297\u751f\u7269\u8cea\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u304c\u4f4e\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u6b21\u306e\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n<ul>\n<li>\u6297\u751f\u7269\u8cea\u3092\u5206\u89e3\u307e\u305f\u306f\u6539\u5909\u3057\u3066\u305d\u308c\u3089\u3092\u4e0d\u6d3b\u6027\u5316\u3059\u308b\u9175\u7d20\u306e\u7523\u751f\u3092\u523a\u6fc0\u3057\u307e\u3059(1)\u3002<\/li>\n<li>\u6297\u751f\u7269\u8cea\u306e\u5165\u53e3\u3092\u306a\u304f\u3059\u304b\u3001\u307e\u305f\u306f\u52b9\u679c\u3092\u767a\u63ee\u3059\u524d\u306b\u6297\u751f\u7269\u8cea\u3092\u653e\u51fa\u3059\u308b\u30dd\u30f3\u30d7\u306e\u958b\u767a\u3092\u4fc3\u9032\u3057\u307e\u3059\uff082\uff09\u3002<\/li>\n<\/ul>\n<ul>\n<li>\u6297\u751f\u7269\u8cea\u304c\u7d50\u5408\u3059\u308b\u5206\u5b50\uff08\u6297\u751f\u7269\u8cea\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\uff09\u3092\u5909\u66f4\u307e\u305f\u306f\u9664\u53bb\u3059\u308b\u3002<\/li>\n<\/ul>\n<p>\u3053\u308c\u306f\u3001\u5bfe\u5fdc\u3059\u308b\u6297\u751f\u7269\u8cea\u304c\u4f7f\u7528\u3055\u308c\u308b\u3068\u3001\u3053\u308c\u3089\u306e\u6297\u751f\u7269\u8cea\u306b\u5bfe\u3059\u308b\u8010\u6027\u7d30\u83cc\u304c\u751f\u304d\u6b8b\u308b\u3053\u3068\u3092\u610f\u5473\u3059\u308b\u3002\u7af6\u5408\u76f8\u624b\u304c\u6392\u9664\u3055\u308c\u3066\u3044\u308b\u3068\u3044\u3046\u4e8b\u5b9f\u306e\u305f\u3081\u306b\u3001\u5f7c\u3089\u306f\u3088\u308a\u826f\u3044\u5897\u6b96\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<br \/>\n\u3055\u3089\u306b\u3001\u3053\u306e\u8010\u6027\u306f\u300c\u8010\u6027\u907a\u4f1d\u5b50\u300d\u306b\u3088\u3063\u3066\u4f1d\u9054\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<ul>\n<li>\u30c9\u30fc\u30bf\u30bb\u30eb\u306b<\/li>\n<li>\u6b7b\u3093\u3060\u7d30\u83cc\u304b\u3089\u306e\u6442\u53d6\u7d4c\u7531 (3)<\/li>\n<li>\u6c34\u5e73\u907a\u4f1d\u5b50\u79fb\u8ee2 (4)<\/li>\n<li>\u30a6\u30a4\u30eb\u30b9\u3092\u901a\u3057\u3066 (5)<\/li>\n<\/ul>\n<p><strong>\u6297\u751f\u7269\u8cea\u306e\u3042\u3089\u3086\u308b\u9069\u7528\u306f\u3001\u62b5\u6297\u6027\u306e\u767a\u9054\u3092\u4fc3\u9032\u3057\u307e\u3059\uff08<\/strong><strong>Robert, <\/strong><strong>2019\uff09\u3002\u77ed\u671f\u9593\u306e\u4f7f\u7528\u3001\u306b<\/strong><a href=\"https:\/\/ew-nutrition.com\/antibiotic-reduction-the-increased-importance-of-high-level-biosecurity\/\">\u3088\u308a<strong>\u826f\u3044\u751f\u7269\u5b89\u5168\u6027<\/strong><\/a><strong>\u3001\u307e\u305f\u306f\u4f4e\u7528\u91cf\u3067\u306e\u9069\u7528\u306f\u3001\u7d30\u83cc\u306b\u9069\u5fdc\u3059\u308b\u3088\u308a\u826f\u3044\u6a5f\u4f1a\u3092\u4e0e\u3048\u307e\u3059\u3002<\/strong><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<h3>\u00a0\u30d0\u30af\u30c6\u30ea\u30aa\u30d5\u30a1\u30fc\u30b8<\/h3>\n<p>\u30d5\u30a1\u30fc\u30b8\u6cbb\u7642\u306e\u5b9f\u9a13\u7684\u4f7f\u7528\u306f\u3001\u75be\u60a3\u306e\u9032\u884c\u304a\u3088\u3073\u58ca\u6b7b\u6027\u8178\u708e\u306e\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u306e\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059 (Miller, 2010)\u3002\u30d0\u30af\u30c6\u30ea\u30aa\u30d5\u30a1\u30fc\u30b8\u30ab\u30af\u30c6\u30eb\u306e\u7d4c\u53e3\u9069\u7528\u306b\u3088\u308a\u3001Miller\u306f\u3001\u672a\u51e6\u7406\u306e\u7fa4\u3068\u6bd4\u8f03\u3057\u3066<em>C.perfringens<\/em>\u611f\u67d3\u30d6\u30ed\u30a4\u30e9\u30fc\u306792\uff05\u6b7b\u4ea1\u7387\u3092\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002<\/p>\n<p>\u4f5c\u7528\u30e2\u30fc\u30c9\uff1a\u30d0\u30af\u30c6\u30ea\u30aa\u30d5\u30a1\u30fc\u30b8\u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u9ad8\u5ea6\u306b\u9032\u5316\u3057\u305f\u9175\u7d20\u3067\u3042\u308b\u30a8\u30f3\u30c9\u30ea\u30b7\u30f3\u306f\u3001\u30d5\u30a1\u30fc\u30b8\u524d\u4ee3\u653e\u51fa\u306e\u305f\u3081\u306b\u7d30\u83cc\u7d30\u80de\u58c1\u3092\u6d88\u5316\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\uff08Fischetti, 2010\uff09\u3002\u3057\u304b\u3057\u3001\u30d5\u30a1\u30fc\u30b8\u6cbb\u7642\u306f\u307e\u3060EFSA\u306b\u3088\u3063\u3066\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n<h2>\u4e88\u9632<\/h2>\n<p>\u75c5\u6c17\u3092<strong>\u4e88\u9632<\/strong>\u3059\u308b\u3053\u3068\u306f\u3001\u5e38\u306b\u826f\u304f\u3001\u3088\u308a\u8cbb\u7528\u5bfe\u52b9\u679c\u304c\u9ad8\u3044\u3067\u3059\u3002<\/p>\n<p>\u305d\u308c\u3067\u306f\u3001\u3069\u306e\u3088\u3046\u306b\u884c\u3046\u3079\u304d\u3067\u3059\u304b\uff1f<\/p>\n<p><em>C.perfringens<\/em>\u306e\u5897\u6b96\u3092\u652f\u6301\u3059\u308b\u6761\u4ef6\u3092\u9632\u6b62\u3057\u3001\u5bbf\u4e3b\u306e\u514d\u75ab\u5fdc\u7b54\u3092\u5f37\u5316\u3059\u308b\u3053\u3068\u306f\u3001\u75be\u60a3\u306e\u78ba\u7387\u3092\u4f4e\u4e0b\u3055\u305b\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u7d20\u56e0\u3092\u6392\u9664\u3059\u308b\u3053\u3068\u306b\u52a0\u3048\u3066\u3001\u4e3b\u306a\u76ee\u6a19\u306f\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n<ul>\n<li><a href=\"https:\/\/ew-nutrition.com\/controlling-necrotic-enteritis\/\">\u00a0\u8178\u5185\u7d30\u83cc\u53e2<\/a>\u306e\u30d0\u30e9\u30f3\u30b9<\/li>\n<li>\u8178\u6a5f\u80fd\u304a\u3088\u3073\u5b8c\u5168\u6027\u306e\u6700\u9069\u5316<\/li>\n<li>\u514d\u75ab\u306e\u7dad\u6301<\/li>\n<\/ul>\n<h3>\u30d0\u30a4\u30aa\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3<\/h3>\n<p>\u58ca\u6b7b\u6027\u8178\u708e\u306b\u7f79\u60a3\u3057\u3066\u3044\u308b\u9d8f\u304b\u3089\u5358\u96e2\u3055\u308c\u305f<em>Clostridium<\/em>\u682a\u306e\u307b\u3068\u3093\u3069\u306f\u3001\u5b9f\u9a13\u7684\u306b\u3053\u306e\u75be\u60a3\u3092\u8a98\u767a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u5065\u5eb7\u306a\u9d8f\u304b\u3089\u5358\u96e2\u3055\u308c\u305f\u682a\u306f\u3067\u304d\u306a\u3044\u3068\u3044\u3046\u8a3c\u62e0\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u7279\u5b9a\u306e\u682a\u306e\u307f\u304c\u554f\u984c\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\uff08Ducatelle, 2010\uff09\u3002<\/p>\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u3053\u308c\u3089\u306e\u75c5\u539f\u6027\u682a\u3092\u8fb2\u5834\u5185\u306b\u5165\u308c\u306a\u3044\u304c\u6700\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n<ul>\n<li>\u53b3\u683c\u306a<a href=\"https:\/\/ew-nutrition.com\/5-principles-to-consider-when-designing-biosecurity-programmes\/\"> \u30d0\u30a4\u30aa\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3<\/a>\u5bfe\u7b56\uff01<\/li>\n<\/ul>\n<ul>\n<li>\u5404\u9d8f\u820e\u306e\u8863\u985e\u3001\u30d6\u30fc\u30c4\u3001\u624b\u6d17\u3044\/\u6d88\u6bd2\u8a2d\u5099\u3092\u5206\u3051\u3066\u304a\u304f<\/li>\n<li>\u65b0\u3057\u3044\u9d8f\u7fa4\u306e\u5c0e\u5165\u306714\u65e5\u4ee5\u4e0a\u306e\u7a7a\u820e\u671f\u9593\u3092\u8a2d\u3051\u308b<\/li>\n<\/ul>\n<h3>\u30b3\u30af\u30b7\u30b8<strong>\u30a6\u30e0<\/strong>\u75c7\u306b\u5bfe\u3059\u308b\u5177\u4f53\u7684\u306a\u5bfe\u7b56<\/h3>\n<ol>\n<li><strong>\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e<\/strong><\/li>\n<\/ol>\n<p>\u5bc4\u751f\u866b\u5b66\u8005\u306b\u3088\u308b\u3068\u3001\u30cb\u30ef\u30c8\u30ea\u306b\u306f7\uff5e9\u7a2e\u306e<em>\u30a2\u30a4\u30e1\u30ea\u30a2<\/em>\u304c\u898b\u3064\u304b\u3063\u3066\u304a\u308a\u3001\u4e92\u3044\u306b\u4ea4\u5dee\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u52b9\u679c\u7684\u306a\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306f\u3001\u6700\u3082\u91cd\u8981\u306a\u75c5\u539f\u6027<em>\u30a2\u30a4\u30e1\u30ea\u30a2\u7a2e(E.acervulina\u3001E.maxima\u3001E.tenella\u3001E.necatrix\u3001E.brunetti<\/em>)\u306e\u80de\u5b50\u5f62\u6210\u30aa\u30fc\u30b7\u30b9\u30c8\u3092\u542b\u307e\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u30ef\u30af\u30c1\u30f3\u306b\u542b\u307e\u308c\u308b\u7a2e\u304c\u591a\u3044\u307b\u3069\u826f\u3044\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u6b63\u3057\u3044\u65b9\u6cd5\u3092\u9069\u7528\u3057\u306a\u3044\u5834\u5408\u3001\u30ef\u30af\u30c1\u30f3\u306f\u52b9\u679c\u304c\u306a\u3044\u304b\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u9d8f\u3092\u767a\u751f\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08Mitchell, 2017\uff09\u3002<\/p>\n<ol>\n<li><strong>\u6297\u30b3\u30af\u30b7<\/strong><strong>\u30b8\u30a6\u30e0\u5264<\/strong><\/li>\n<\/ol>\n<p>\u8010\u6027\u306e\u767a\u9054\u3092\u9632\u3050\u306b\u306f\u3001\u7570\u306a\u308b\u4f5c\u7528\u69d8\u5f0f\u3092\u6709\u3059\u308b\u5316\u5b66\u7269\u8cea\uff08\u5408\u6210\u5316\u5408\u7269\uff09\u304a\u3088\u3073\u30a4\u30aa\u30ce\u30d5\u30a9\u30a2\uff08\u30dd\u30ea\u30a8\u30fc\u30c6\u30eb\u7cfb\u6297\u751f\u7269\u8cea\uff09\u4ea4\u4e92\u306b\u4f7f\u7528\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n<p>\u30a4\u30aa\u30ce\u30d5\u30a9\u30a2\u306b\u306f\u3001\u7279\u5b9a\u306e\u4f5c\u7528\u6a5f\u5e8f\u304c\u3042\u308a\u3001\u9d8f\u306b\u611f\u67d3\u3059\u308b\u524d\u306b\u30aa\u30fc\u30b7\u30b9\u30c8\u3092\u6bba\u3057\u307e\u3059\u3002\u30a4\u30aa\u30ce\u30d5\u30a9\u30a2\u5206\u5b50\u306f\u975e\u5e38\u306b\u5c0f\u3055\u3044\u305f\u3081\u3001\u30b9\u30dd\u30ed\u30be\u30a4\u30c8\u306e\u5916\u819c\u306b\u53d6\u308a\u8fbc\u307e\u308c\u3066\u62e1\u6563\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u305d\u308c\u306f\u6fc3\u5ea6\u52fe\u914d\u3092\u6e1b\u5c11\u3055\u305b\u3001\u30b9\u30dd\u30ed\u30be\u30a4\u30c8\u5185\u306e\u6c34\u306e\u84c4\u7a4d\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u305d\u306e\u7834\u88c2\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/p>\n<h3>\u30c0\u30a4\u30a8\u30c3\u30c8<\/h3>\n<h4>\u7a40\u7269\u4e2d\u306e\u975e\u30c7\u30f3\u30d7\u30f3\u591a\u7cd6\u985e\uff08NSP\uff09\u306e\u6700\u5c0f\u5316<\/h4>\n<p><img decoding=\"async\" class=\"wp-image-55511 size-medium alignleft\" src=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-300x225.jpg 300w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-150x113.jpg 150w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-120x90.jpg 120w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-36x27.jpg 36w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-533x400.jpg 533w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-225x169.jpg 225w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-80x60.jpg 80w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br.jpg 864w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-48x36.jpg 48w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-64x48.jpg 64w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-28x21.jpg 28w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-718x539.jpg 718w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-280x210.jpg 280w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-500x376.jpg 500w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-24x18.jpg 24w, https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/broiler-house-2_pr-br-170x128.jpg 170w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<p><em>C.perfringens<\/em>\u306e\u300c\u6442\u98df\u300d\u3092\u9632\u3050\u306b\u306f\u3001\u5c0f\u9ea6\u3001\u5c0f\u9ea6\u526f\u7523\u7269\u3001\u5927\u9ea6\u306a\u3069\u306e\u6c34\u6eb6\u6027\u3067\u3042\u308b\u304c\u96e3\u6d88\u5316\u6027\u306e\u975e\u30c7\u30f3\u30d7\u30f3\u591a\u7cd6\u985e(NSP)\u306e\u9ad8\u3044\u542b\u6709\u91cf\u3092\u907f\u3051\u308b\u304b\u3001\u5c11\u306a\u304f\u3068\u3082\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u30ad\u30b7\u30e9\u30ca\u30fc\u30bc\u3092\u98fc\u6599\u914d\u5408\u306b\u542b\u3081\u308b\u3053\u3068\u3067\u3001NS\u975e\u30c7\u30f3\u30d7\u30f3\u591a\u7cd6\u985e(NSP)\u306e\u6709\u5bb3\u306a\u5f71\u97ff\u3092\u4f4e\u6e1b\u3057\u3001\u98fc\u6599\u30a8\u30cd\u30eb\u30ae\u30fc\u5229\u7528\u7387\u3092\u6539\u5584\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u7a40\u7269\u306e\u4ee3\u308f\u308a\u306b\u3001\u30c8\u30a6\u30e2\u30ed\u30b3\u30b7\u3092\u98fc\u6599\u306b\u542b\u3081\u308b\u3053\u3068\u304c\u53ef\u80fd\u6027\u3067\u3059\u3002\u3053\u308c\u306f\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u542b\u6709\u91cf\u304c\u9ad8\u304f\u3001\u6804\u990a\u7d20\u306e\u5229\u7528\u304c\u9ad8\u3044\u305f\u3081\u3001\u30d6\u30ed\u30a4\u30e9\u30fc\u306e\u98fc\u6599\u306b\u6700\u9069\u306a\u6210\u5206\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4>\u4f4e\u30bf\u30f3\u30d1\u30af\/\u9ad8\u6d88\u5316\u6027\u30a2\u30df\u30ce\u9178\u3092\u542b\u3080\u98fc\u6599\u51e6\u65b9<\/h4>\n<p>\u7d50\u6676\u6027\u30a2\u30df\u30ce\u9178\u3092\u88dc\u7d66\u3057\u305f\u4f4e\u30bf\u30f3\u30d1\u30af\u98fc\u6599\u3092\u4e0e\u3048\u308b\u3053\u3068\u306f\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u306e\u306b\u6709\u76ca\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08Dahiya, 2007\uff09\u3002\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6d88\u5316\u7387\u3092\u6539\u5584\u3057\u3001<em>C.perfringens<\/em>\u306e\u5897\u6b96\u3092\u6e1b\u5c11\u3055\u305b\u308b\u305f\u3081\u306b\u3001\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u3092\u98fc\u6599\u306b\u6dfb\u52a0\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<h4>\u98df\u4e8b\u4e2d\u306e\u52d5\u7269\u6027\u8102\u80aa\u306e\u56de\u907f\/\u6700\u5c0f\u5316<\/h4>\n<p>\u52d5\u7269\u6027\u8102\u80aa\u306f\u3001<em>C.perfringens<\/em>\u83cc\u306e\u6570\u3092\u5897\u3084\u3059\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u305d\u308c\u3089\u306f\u690d\u7269\u6027\u8102\u80aa\u6e90\u306b\u7f6e\u304d\u63db\u3048\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h4>\u98fc\u6599\u5f62\u72b6<\/h4>\n<p>\u98fc\u6599\u5f62\u614b\u306b\u95a2\u3057\u3066\u306f\u3001Engberg(2002) \u306f\u3001\u30da\u30ec\u30c3\u30c8\u98fc\u6599\u3092\u4e0e\u3048\u305f\u9d8f\u306f\u3001\u30de\u30c3\u30b7\u30e5\u98fc\u6599\u3092\u4e0e\u3048\u305f\u9d8f\u3088\u308a\u3082\u76f2\u8178\u3068\u76f4\u8178\u3067<em>C.perfringens<\/em>\u83cc\u306e\u6570\u304c\u6e1b\u5c11\u3057\u305f\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002Branton\uff081987\uff09\u306f\u3001\u30cf\u30f3\u30de\u30fc\u7c89\u7815\u98fc\u6599\u3088\u308a\u3082\u30ed\u30fc\u30e9\u30fc\u30df\u30eb\u52a0\u5de5\u98fc\u6599\uff08\u7c97\u7c89\u7815\uff09\u3092\u4f9b\u7d66\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u6b7b\u4ea1\u7387\u304c\u4f4e\u3044\u3053\u3068\u3092\u5831\u544a\u3057\u307e\u3057\u305f\u3002<\/p>\n<h3>\u6dfb\u52a0\u5264<\/h3>\n<p>\u6dfb\u52a0\u5264\u306f\u3001<em>C.perfringens<\/em>\u306e\u5897\u6b96\u3092\u9632\u3050\u305f\u3081\u3001\u307e\u305f\u306f<em>C.perfringens<\/em>\u306e\u5897\u6b96\u3092\u9632\u3050\u65b9\u6cd5\u3067\u74b0\u5883\u6761\u4ef6\u3092\u5909\u66f4\u3059\u308b\u305f\u3081\u306b\u4f7f\u7528\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<h4>\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9<\/h4>\n<p>\u3053\u308c\u3089\u306e\u751f\u304d\u305f\u5fae\u751f\u7269\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306f\u3001\u8178\u5185\u5fae\u751f\u7269\u53e2\u3092\u78ba\u7acb\u3001\u7dad\u6301\u307e\u305f\u306f\u518d\u78ba\u7acb\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n<p>\u4f5c\u7528\u6a5f\u5e8f:<\/p>\n<ul>\n<li>\u57fa\u8cea\u3068\u4ed8\u7740\u90e8\u4f4d\u3092\u6c42\u3081\u3066\u75c5\u539f\u83cc\u3068\u7af6\u5408\u3059\u308b<\/li>\n<li>\u75c5\u539f\u83cc\u306e\u5897\u6b96\u3092\u6291\u5236\u3059\u308b\u6297\u83cc\u7269\u8cea\u3092\u7523\u751f\u3059\u308b (Gillor, 2008)<\/li>\n<li>\u30a8\u30f3\u30c6\u30ed\u30c8\u30ad\u30b7\u30f3\u3092\u7d50\u5408\u3057\u3066\u3001\u4e2d\u548c\u3059\u308b\uff08Mathipa, 2017\uff09<\/li>\n<\/ul>\n<p>\u5bbf\u4e3b\u306e\u514d\u75ab\u6a5f\u80fd\u3092\u4fc3\u9032\u3059\u308b (Yang, 2012)<\/p>\n<h4><strong>\u30d7\u30ec\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9<\/strong><\/h4>\n<ul>\n<li>\n<ul>\n<li>\u3053\u308c\u3089\u306e\u98fc\u6599\u6210\u5206\u306f\u3001\u8178\u5185\u306e\u6709\u76ca\u306a\u7d30\u83cc\u3092\u5897\u6b96\u3059\u308b\u305f\u3081\u306e\u6804\u990a\u7d20\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n<p>\u4f5c\u7528\u6a5f\u5e8f:<\/p>\n<ul>\n<li>D\u30de\u30f3\u30ce\u30fc\u30b9\u307e\u305f\u306f\u30d5\u30eb\u30af\u30c8\u30fc\u30b9\u3001\u9d8f\u306b\u3088\u3063\u3066\u6d88\u5316\u3055\u308c\u306a\u3044\u30c7\u30f3\u30d7\u30f3\u306f\u3001\u8178\u5185\u7d30\u83cc\u53e2\u306e\u300c\u826f\u3044\u300d\u6210\u9577\u304a\u3088\u3073\u6d3b\u6027\u3092\u9078\u629e\u7684\u306b\u4fc3\u9032\u3057\u307e\u3059\u3002<\/li>\n<li>\u30d5\u30eb\u30af\u30c8\u30aa\u30ea\u30b4\u7cd6\u306f\u3001\u8178\u5185\u306e<em>C.perfringens<\/em>\u304a\u3088\u3073\u5927\u8178\u83cc\u3092\u6e1b\u5c11\u3055\u305b\u3001<em>Lactobacillus<\/em>\u5c5e\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002(Kim, 2011)<\/li>\n<li>\u30ac\u30e9\u30af\u30c8\u30aa\u30ea\u30b4\u7cd6\u306f\u3001\u30e9\u30af\u30c6\u30a3\u30b9\u30d9\u30fc\u30b9\u306e\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u3001<em>Bifidobacterium<\/em>\u5c5e\u306e\u5897\u6b96\u3092\u9078\u629e\u7684\u306b\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059(Jung, 2008)\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h4>\u6709\u6a5f\u9178<\/h4>\n<p>\u6709\u6a5f\u9178\u306f\u3001\u8178\u306e\u5065\u5eb7\u3092\u6539\u5584\u3059\u308b\u305f\u3081\u306b\u3001\u52d5\u7269\u306e\u98fc\u6599\u306b\u3088\u304f\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u4f5c\u7528\u6a5f\u5e8f:<\/p>\n<ul>\n<li>pH\u4f4e\u4e0b\u306f\u3001\u6709\u76ca\u306a\u7d30\u83cc\u304c\u5897\u6b96\u3057\u307e\u3059<\/li>\n<li>\u30ab\u30d7\u30ea\u30eb\u9178\u306f\u3001<em>C.perfringens<\/em>\u3092\u6291\u5236\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u306e\u5229\u7528\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30b5\u30eb\u30e2\u30cd\u30e9\u5c5e\u3082\u963b\u5bb3\u3057\u307e\u3059(Skrivanova, 2006)\u3002<\/li>\n<\/ul>\n<p>\u30e9\u30a6\u30ea\u30f3\u9178\u3001\u30af\u30a8\u30f3\u9178\u3001\u30aa\u30ec\u30a4\u30f3\u9178\u3001\u30ea\u30ce\u30fc\u30eb\u9178\u3001\u4e2d\u9396\u8102\u80aa\u9178\uff08C8-C14\uff09\u306f\u3001<em>C.perfringens<\/em><em>\u306e<\/em> \u5897\u6b96\u3092\u59a8\u3052\u307e\u3059\u3002<\/p>\n<h4>\u690d\u7269\u5206\u5b50<\/h4>\n<p><a href=\"https:\/\/ew-nutrition.com\/challenging-times-for-broilers\/\"><strong>\u690d\u7269\u5206\u5b50<\/strong><\/a>\u306f\u3001\u4f55\u4e16\u7d00\u306b\u3082\u308f\u305f\u3063\u3066\u75c5\u539f\u4f53\u306b\u5bfe\u3057\u3066\u4f7f\u7528\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u4e00\u822c\u306b\u3001\u3053\u308c\u3089\u306e\u7269\u8cea\u306e2\u3064\u306e\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u306f\u3001<em>C.perfringens<\/em>\u306b\u5bfe\u3057\u3066\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h5>\u30bf\u30f3\u30cb\u30f3<\/h5>\n<ul>\n<li>\u591a\u304f\u306e\u7814\u7a76\u3067\u306f\u3001\u8815\u866b\u3001\u30a2\u30a4\u30e1\u30ea\u30a2\u3001\u30a6\u30a4\u30eb\u30b9\u3001\u7d30\u83cc\u306a\u3069\u306e\u3055\u307e\u3056\u307e\u306a\u75c5\u539f\u4f53\u306b\u5bfe\u3059\u308b\u30bf\u30f3\u30cb\u30f3\u306e\u6709\u52b9\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li>\u6817\u3068\u30b1\u30d6\u30e9\u30b3\u306e\u6728\u304b\u3089\u306e\u62bd\u51fa\u7269\u306f\u3001<em>C.perfringens<\/em>\u3060\u3051\u3067\u306a\u304f\u3001\u305d\u306e\u6bd2\u7d20\u306b\u5bfe\u3057\u3066\u3082\u6709\u52b9\u3067\u3059 (Elizando, 2010)\u3002<\/li>\n<li>\u58ca\u6b7b\u6027\u8178\u708e\u306e2\u3064\u306e\u7d20\u56e0\u3067\u3042\u308b\u30a2\u30a4\u30e1\u30ea\u30a2\u3068\u30b5\u30eb\u30e2\u30cd\u30e9\u5c5e\u306b\u5bfe\u3059\u308b\u30bf\u30f3\u30cb\u30f3\u306e\u6d3b\u6027(Ce, 2011)\u3002<\/li>\n<\/ul>\n<h5>\u30a8\u30c3\u30bb\u30f3\u30b7\u30e3\u30eb\u30aa\u30a4\u30eb<\/h5>\n<ul>\n<li>\n<ul>\n<li>\u305d\u308c\u3089\u306e\u758e\u6c34\u6027\u7279\u6027\u306b\u3088\u308a\u3001<em>C.perfringens<\/em>\u83cc\u306e\u819c\u306e\u8102\u8cea\u3068\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/li>\n<li>\u305d\u308c\u3089\u306f\u7d30\u83cc\u306e\u819c\u306b\u7d44\u307f\u8fbc\u307e\u308c\u3001\u305d\u306e\u5b8c\u5168\u6027\u3092\u7834\u58ca\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<li>\u3053\u308c\u306b\u3088\u308a\u3001\u30a4\u30aa\u30f3\u3084ATP\u306a\u3069\u306e\u4ed6\u306e\u5c0f\u5206\u5b50\u306b\u5bfe\u3059\u308b\u7d30\u80de\u819c\u306e\u900f\u904e\u6027\u304c\u9ad8\u307e\u308a\u3001\u7d30\u80de\u819c\u4e0a\u306e\u96fb\u6c17\u5316\u5b66\u7684\u52fe\u914d\u304c\u6e1b\u5c11\u3057\u3001\u7d30\u80de\u306e\u540c\u7b49\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u5931\u308f\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n<p><em>Clostridium\u5c5e<\/em>\u3078\u306e\u76f4\u63a5\u7684\u306a\u52b9\u679c\u306b\u52a0\u3048\u3066\u3001\u591a\u304f\u306e\u690d\u7269\u5206\u5b50\u306f<a href=\"https:\/\/ew-nutrition.com\/poultry-health-and-welfare-phytomolecules-for-poultry-diets\/\"><strong>\u8178\u306e\u5065\u5eb7\u3092\u6539\u5584<\/strong><\/a>\u3057\u3001<em>Clostridium\u5c5e<\/em>\u306e\u5897\u6b96\u3068\u58ca\u6b7b\u6027\u8178\u708e\u3092\u9632\u3050\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/li>\n<\/ul>\n<h4>\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\/\u7d30\u83cc\u6027\u6bd2\u7d20\u7d50\u5408\u5264<\/h4>\n<p>\u3053\u308c\u3089\u306e\u7d50\u5408\u5264\u306b\u306f\u3001\u6b21\u306e 2 \u3064\u306e\u4f5c\u7528\u30e2\u6a5f\u5e8f\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<ul>\n<li>\u30de\u30a4\u30b3\u30c8\u30ad\u30b7\u30f3\u306e\u7d50\u5408\u3001\u8178\u4e0a\u76ae\u306e\u640d\u50b7\u3092\u8efd\u6e1b\u307e\u305f\u306f\u9632\u6b62\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u3001<em>Clostridium<\/em>\u5897\u6b96\u306e\u524d\u63d0\u6761\u4ef6\u304c\u751f\u6210\u3055\u308c\u307e\u305b\u3093\u3002<\/li>\n<li><em>C.perfringens<\/em>\u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u7d50\u5408\u6bd2\u7d20\u306f\u3001\u75c5\u5909\u306e\u767a\u751f\u307e\u305f\u306f\u91cd\u75c7\u5ea6\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\uff1a<\/li>\n<\/ul>\n<p>\u03b1-\u30c8\u30ad\u30b7\u30f3\u3001\u30db\u30b9\u30db\u30ea\u30d1\u30fc\u30bcC\u306f\u3001\u819c\u30ea\u30f3\u8102\u8cea\u3092\u52a0\u6c34\u5206\u89e3\u3057\u3001\u8d64\u8840\u7403\u3001\u767d\u8840\u7403\u3001\u7b4b\u7d30\u80de\u3001\u5185\u76ae\u7d30\u80de\u306b\u640d\u50b7\u3092\u4e0e\u3048\u3001\u305d\u308c\u3089\u306e\u8102\u80aa\u5206\u89e3\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059 (Songer, 1996)\u3002\u3053\u308c\u306f\u58ca\u6b7b\u3068\u7d44\u7e54\u306e\u640d\u50b7\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002<\/p>\n<ul>\n<li>\u4e3b\u8981\u306a\u75c5\u539f\u6027\u56e0\u5b50\u3067\u3042\u308bNetB\u6bd2\u7d20\u306e\u7d50\u5408\u306f\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306e\u91cd\u75c7\u5ea6\u3092\u8efd\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<h2>\u7d50\u8ad6<\/h2>\n<p>\u6297\u751f\u7269\u8cea\u3068\u30a4\u30aa\u30ce\u30d5\u30a9\u30a2\u306e\u4f7f\u7528\u304c\u6e1b\u5c11\u3059\u308b\u50be\u5411\u306f\u3001\u5bb6\u79bd\u751f\u7523\u306b\u304a\u3051\u308b\u58ca\u6b7b\u6027\u8178\u708e\u306e\u767a\u751f\u7387\u306e\u5897\u52a0\u306b\u8ca2\u732e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u7121\u75c7\u5019\u6027\u306e\u58ca\u6b7b\u6027\u8178\u708e\u306f\u4e00\u822c\u7684\u306b\u6c17\u3065\u304b\u306a\u3044\u305f\u3081\u3001\u98fc\u6599\u52b9\u7387\u304c\u4f4e\u4e0b\u3057\u3001\u5bb6\u79bd\u751f\u7523\u8005\u306b\u3068\u3063\u3066\u7d4c\u6e08\u7684\u640d\u5931\u306e\u5927\u304d\u306a\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u6700\u9069\u306a\u8178\u306e\u5065\u5eb7\u72b6\u614b\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u306f\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306e\u767a\u751f\u3092\u9632\u3050\u305f\u3081\u306e\u9375\u3068\u306a\u308a\u307e\u3059\u3002\u6297\u751f\u7269\u8cea\u3092\u542b\u307e\u306a\u3044\u5bb6\u79bd\u751f\u7523\u306e\u6642\u4ee3\u3067\u306f\u3001\u3053\u306e\u58ca\u6ec5\u7684\u306a\u75be\u75c5\u3092\u5236\u5fa1\u3059\u308b\u305f\u3081\u306b\u3001\u3053\u306e\u75c5\u539f\u7d30\u83cc\u306b\u5bfe\u3057\u3066\u3082\u305d\u306e\u7d20\u56e0\u306b\u5bfe\u3057\u3066\u4f5c\u7528\u3059\u308b\u4ee3\u66ff\u624b\u6bb5\u3092\u691c\u8a0e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p><img decoding=\"async\" class=\"size-medium wp-image-46440 aligncenter\" src=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/2020\/09\/02_products-300x199.png\" alt=\"\" width=\"300\" height=\"199\" \/><\/p>\n<p>&nbsp;<\/p>\n<h4>References<\/h4>\n<p>Annett, C.B., J. R. Viste, M. Chirino-Trejo, H. L. Classen, D. M. Middleton, and E. Simko. \u201cNecrotic enteritis: effect of barley, wheat and corn diets on proliferation of Clostridium perfringens type A.\u201d <em>Avian Pathology <\/em>31 (2002): 599\u2013 602. <a href=\"https:\/\/doi.org\/10.1080\/0307945021000024544\">https:\/\/doi.org\/10.1080\/0307945021000024544<\/a><\/p>\n<p>Antonissen G, F. Van Immerseel, F. Pasmans, R. Ducatelle, F. Haesebrouck, L. Timbermont, M. Verlinden, G.P.J. Janssens, V. Eeckhaut, M. Eeckhout, S. De Saeger, S. Hessenberger, A. Martel, and S. Croubels. \u201cThe mycotoxin deoxynivalenol predisposes for the development of Clostridium perfringens-Induced necrotic enteritis in broiler chickens. <em>PLoS ONE <\/em>9 no. 9 (2014): e108775. <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0108775\">https:\/\/doi.org\/10.1371\/journal.pone.0108775<\/a><\/p>\n<p>Antonissen, G., V. Eeckhaut, K. Van Driessche, L. Onrust , F. Haesebrouck, R. Ducatelle, R.J. Moore, and F. Van Immerseel. \u201cMicrobial Shifts Associated With Necrotic enteritis.\u201d <em>Avian Pathol. <\/em>45 no. 3 (2016): 308-312. <a href=\"https:\/\/doi.org\/10.1080\/03079457.2016.1152625\">https:\/\/doi.org\/10.1080\/03079457.2016.1152625<\/a><\/p>\n<p>Branton, S.L., F.N. Reece, and W.M. Hagler. \u201cInfluence of a wheat diet on mortality of broiler chickens associated with necrotic enteritis.\u201d Poultry Sci. 66 (1987): 1326-1330. <a href=\"https:\/\/doi.org\/10.3382\/ps.0661326\">https:\/\/doi.org\/10.3382\/ps.0661326<\/a><\/p>\n<p>Cejas, E., S. Pinto, F. Prosd\u00f3cimo, M. Batalle, H. Barrios, G. Tellez, and M. De Franceschi. \u201cEvaluation of quebracho red wood (Schinopsis lorentzii) polyphenols vegetable extract for the reduction of coccidiosis in broiler chicks.\u201d <em>International Journal of Poultry Science <\/em>10 no. 5 (2011): 344\u2013349. <a href=\"https:\/\/doi.org\/10.3923\/ijps.2011.344.349\">https:\/\/doi.org\/10.3923\/ijps.2011.344.349<\/a><\/p>\n<p>Collier, C.T., C.L. Hofacre, A.M. Payne, D.B. Anderson, P. Kaiser, R.I. Mackie, and H.R. Gaskins. \u201cCoccidia-induced mucogenesis promotes the onset of necrotic enteritis by supporting Clostridium perfringens growth.\u201d <em>Veterinary Immunology and Immunopathology <\/em>122 (2008):104\u2013115.<\/p>\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.vetimm.2007.10.014\">https:\/\/doi.org\/10.1016\/j.vetimm.2007.10.014<\/a><\/p>\n<p><a href=\"https:\/\/www.academia.edu\/12692646\/Coccidia-induced_mucogenesis_promotes_the_onset_of_necrotic_enteritis_by_supporting_Clostridium_perfringens_growth\">https:\/\/www.academia.edu\/12692646\/Coccidia-induced_mucogenesis_promotes_the_onset_of_necrotic_enteritis_by_supporting_Clostridium_perfringens_growth<\/a><\/p>\n<p>Dahiya, J.P., D. Hoehler, A.G. Van Kessel, and M.D. Drew. \u201cEffect of different dietary methionine sources on intestinal microbial populations in broiler chickens.\u201d <em>Poultry Science <\/em>86 (2007)<em>:<\/em>2358\u20132366<\/p>\n<p><a href=\"https:\/\/doi.org\/10.3382\/ps.2007-00133\">https:\/\/doi.org\/10.3382\/ps.2007-00133<\/a><\/p>\n<p>Dahiya, J.P., D. Hoehler, D.C. Wilkie, A.G. van Kessel, and M.D. Drew. \u201cDietary glycine concentration affects intestinal Clostridium perfringens and Lactobacilli populations in broiler chickens.\u201d <em>Poultry Science <\/em>84 no.12 (2005):1875-85. <a href=\"https:\/\/doi.org\/10.1093\/ps\/84.12.1875\">https:\/\/doi.org\/10.1093\/ps\/84.12.1875<\/a><\/p>\n<p>Diaz Carrasco, J.M., L.M. Redondo, E.A. Redondo, J.E. Dominguez, A.P. Chacana, and M.E. Fernandez Miyakawa. \u201cUse of plant extracts as an effective manner to control Clostridium perfringens induced necrotic enteritis in poultry.\u201d <em>BioMed Research International<\/em> (2016): Article ID 3278359. <a href=\"https:\/\/dx.doi.org\/10.1155\/2016\/3278359\">https:\/\/dx.doi.org\/10.1155\/2016\/3278359<\/a><\/p>\n<p>Ducatelle, R. and F. van Immerseel. \u201cNecrotic enteritis: emerging problem in broilers.\u201d <em>WATTAgNet.com \u2013 Poultry Health and Disease<\/em> (April 9, 2010).<\/p>\n<p><a href=\"https:\/\/www.wattagnet.com\/articles\/5523-necrotic-enteritis-emerging-problem-in-broilers\">https:\/\/www.wattagnet.com\/articles\/5523-necrotic-enteritis-emerging-problem-in-broilers<\/a><\/p>\n<p>Elizondo, A.M.,\u00a0 E.C. Mercado, B.C. Rabinovitz, and M.E. Fernandez-Miyakawa. \u201cEffect of tannins on the in vitro growth of Clostridium perfringens.\u201d <em>Veterinary Microbiology <\/em>145 no. 3-4 (2010): 308\u2013314. <a href=\"https:\/\/doi.org\/10.1016\/j.vetmic.2010.04.003\">https:\/\/doi.org\/10.1016\/j.vetmic.2010.04.003<\/a><\/p>\n<p>Engberg, R.M., M.S. Hedemann, and B.B. Jensen. \u201cThe influence of grinding and pelleting of feed on the microbial composition and activity in the digestive tract of broiler chickens.\u201d \u00b7 <em>British Poultry Science <\/em>43 no. 4 (2002):569-579. <a href=\"https:\/\/doi.org\/10.1080\/0007166022000004480\">https:\/\/doi.org\/10.1080\/0007166022000004480<\/a><\/p>\n<p>Fischetti, V.A. \u201cBacteriophage endolysins: A novel anti-infective to control Gram-positive pathogens.\u201d <em>J Med Microbiol. <\/em>300 no. 6 (2010): 357\u2013362. <a href=\"https:\/\/doi.org\/10.1016\/j.ijmm.2010.04.002\">https:\/\/doi.org\/10.1016\/j.ijmm.2010.04.002<\/a><\/p>\n<p>Gillor, O., A. Etzion and M.A. Riley. \u201cThe dual role of bacteriocins as anti- and probiotics.\u201d <em>Appl Microbiol Biotechnol<\/em>. 81 no. 4 (2008): 591\u2013606. <a href=\"https:\/\/doi.org\/10.1007\/s00253-008-1726-5\">https:\/\/doi.org\/10.1007\/s00253-008-1726-5<\/a><\/p>\n<p>Hassan, J. O., and R. Curtiss III. \u201cVirulent Salmonella typhimurium induced lymphocyte depletion and immunosuppression in chickens.\u201d <em>Infect. Immun.<\/em> 62 (1994):2027\u20132036 <a href=\"https:\/\/doi.org\/10.1128\/IAI.62.5.2027-2036.1994\">https:\/\/doi.org\/10.1128\/IAI.62.5.2027-2036.1994<\/a><\/p>\n<p>Hofacre, C.L., J.A. Smith, and G.F. Mathis. \u201cInvited Review. An optimist\u2019s view on limiting necrotic enteritis and maintaining broiler gut health and performance in today\u2019s marketing, food safety, and regulatory climate.\u201d <em>Poultry Science <\/em>97 (2018):1929\u20131933. <a href=\"https:\/\/dx.doi.org\/10.3382\/ps\/pey082\">https:\/\/dx.doi.org\/10.3382\/ps\/pey082<\/a><\/p>\n<p>Jung, S.J., R. Houde, B. Baurhoo, X. Zhao, and B. H. Lee. \u201cEffects of galacto-oligosaccharides and a bifidobacteria lactis-based probiotic strain on the growth performance and fecal microflora of broiler chickens.\u201d <em>Poultry Science <\/em>87 (2008):1694\u20131699. <a href=\"https:\/\/doi.org\/10.3382\/ps.2007-00489\">https:\/\/doi.org\/10.3382\/ps.2007-00489<\/a><\/p>\n<p>Kaldhusdal and Skjerve. \u201cAssociation between cereal contents in the diet and incidence of necrotic enteritis in broiler chickens in Norway.\u201d <em>Preventive Veterinary Medicine<\/em> 28 (1996):1-16. <a href=\"https:\/\/doi.org\/10.1016\/0167-5877(96)01021-5\">https:\/\/doi.org\/10.1016\/0167-5877(96)01021-5<\/a><\/p>\n<p><a href=\"https:\/\/www.academia.edu\/17521917\/Association_between_cereal_contents_in_the_diet_and_incidence_of_necrotic_enteritis_in_broiler_chickens_in_Norway\">https:\/\/www.academia.edu\/17521917\/Association_between_cereal_contents_in_the_diet_and_incidence_of_necrotic_enteritis_in_broiler_chickens_in_Norway<\/a><\/p>\n<p>Keyburn, A. L., S. A. Sheedy, M. E. Ford, M. M. Williamson, M. M. Awad, J. I. Rood, and R. J. Moore. \u201cAlpha-toxin of Clostridium perfringens is not an essential virulence factor in necrotic enteritis in chickens<em>.\u201d Infect. Immun. <\/em>74 (2006): 6496\u20136500. <a href=\"https:\/\/doi.org\/10.1128\/IAI.00806-06\">https:\/\/doi.org\/10.1128\/IAI.00806-06<\/a><\/p>\n<p>Keyburn, A.L., J.D. Boyce, P. Vaz, T.L. Bannam, M.E. Ford, D. Parker, A. Di Rubbo, J.I. Rood, and R.J. Moore. \u201cNetB, a new toxin that is associated with avian necrotic enteritis caused by Clostridium perfringens.\u201d <em>PLoS Pathog<\/em> 4 no. 2, e26 (2008): 0001-0011. <a href=\"https:\/\/doi.org\/10.1371\/journal.ppat.0040026\">https:\/\/doi.org\/10.1371\/journal.ppat.0040026<\/a><\/p>\n<p>Kim, G.-B., Y. M. Seo , C. H. Kim , and I. K. Paik. \u201cEffect of dietary prebiotic supplementation on the performance, intestinal microflora, and immune response of broilers.\u201d <em>Poultry Science<\/em> 90 (2011):75\u201382. <a href=\"https:\/\/doi.org\/10.3382\/ps.2010-00732\">https:\/\/doi.org\/10.3382\/ps.2010-00732<\/a><\/p>\n<p>Knap, I., B. Lund, A. B. Kehlet, C. Hofacre, and G. Mathis. \u201cBacillus licheniformis prevents necrotic enteritis in broiler chickens.\u201d <em>Avian Diseases <\/em>54 no. 2<em> (2010)<\/em>:931-935. <a href=\"https:\/\/doi.org\/10.1637\/9106-101509-ResNote.1\">https:\/\/doi.org\/10.1637\/9106-101509-ResNote.1<\/a><\/p>\n<p>Knarreborg, A., M.A. Simon, R.M. Engberg, B.B. Jensen, and G.W. Tannock. \u201cEffects of Dietary Fat Source and Subtherapeutic Levels of Antibioticon the Bacterial Community in the Ileum of Broiler Chickensat Various Ages.\u201d <em>Applied and Environmental Microbiology <\/em>68 no. 12 (2002): 5918-5924. <a href=\"https:\/\/doi.org\/0.1128\/AEM.68.12.5918\u20135924.2002\">https:\/\/doi.org\/0.1128\/AEM.68.12.5918\u20135924.2002<\/a><\/p>\n<p>Kocher, A. and M. Choct. \u201cImproving broiler chicken performance. The efficacy of organic acids, prebiotics and enzymes in controlling necrotic enteritis.\u201d <em>Australian Government-Rural Industries Research and Development Corporation<\/em>. Publ. no. 08\/149 (2008).<\/p>\n<p><a href=\"https:\/\/www.agrifutures.com.au\/wp-content\/uploads\/publications\/08-149.pdf\">https:\/\/www.agrifutures.com.au\/wp-content\/uploads\/publications\/08-149.pdf<\/a><\/p>\n<p>Kondo, F. \u201cIn vitro lecithinase activity and sensitivity to 22 antimicrobial agents of Clostridium perfringens isolated from necrotic enteritis of broiler chickens.\u201d <em>Research in veterinary Science<\/em> 45 (1988): 337-340. <a href=\"https:\/\/doi.org\/10.1016\/S0034-5288(18)30961-5\">https:\/\/doi.org\/10.1016\/S0034-5288(18)30961-5<\/a><\/p>\n<p>Kubena, L.F., J.A. Byrd, C.R. Young, and D.E. Corrier. \u201cEffects of tannic acid on cecal volatile fatty acids and susceptibility to Salmonella typhimurium colonization in broiler chicks.\u201d <em>Poultry Science<\/em> 80, no. 9 (2001): 1293\u20131298. <a href=\"https:\/\/doi.org\/10.1093\/ps\/80.9.1293\">https:\/\/doi.org\/10.1093\/ps\/80.9.1293<\/a><\/p>\n<p>Los, F.C.O., T.M. Randis, R.V. Aroian, and A.J. Ratner. \u201cRole of pore-forming toxins in bacterial infectious diseases.\u201d <em>Microbiology and Molecular Biology Reviews<\/em> 77 (2013): 173-207 <a href=\"https:\/\/doi.org\/10.1128\/MMBR.00052-12\">https:\/\/doi.org\/10.1128\/MMBR.00052-12<\/a><\/p>\n<p>M&#8217;Sadeq S.A., Shubiao Wu, Robert A. Swick, Mingan Choct. \u201cTowards the control of necrotic enteritis in broiler chickens with in-feed antibiotics phasing-out worldwide.\u201d <em>Animal Nutrition <\/em>1 (2015): 1-11. <a href=\"https:\/\/dx.doi.org\/10.1016\/j.aninu.2015.02.004\">https:\/\/dx.doi.org\/10.1016\/j.aninu.2015.02.004<\/a><\/p>\n<p>Mathipa, M.G. and M.S. Thantsha. \u201cProbiotic engineering: towards development of robust probiotic strains with enhanced functional properties and for targeted control of enteric pathogens.\u201d <em>Gut Pathog. <\/em>9 no. 28 (2017). <a href=\"https:\/\/doi.org\/10.1186\/s13099-017-0178-9\">https:\/\/doi.org\/10.1186\/s13099-017-0178-9<\/a><\/p>\n<p>McDevitt, R.M., J.D. Brooker, T. Acamovic, and N.H.C. Sparks. \u201cNecrotic enteritis, a continuing challenge for the poultry industry.\u201d <em>World\u2019s Poultry Science Journal <\/em>62; World\u2019s Poultry Science Association (June 2006). <a href=\"https:\/\/doi.org\/10.1079\/WPS200593\">https:\/\/doi.org\/10.1079\/WPS200593<\/a><\/p>\n<p>Miller, R.W., J. Skinner, A. Sulakvelidze, G.F. Mathis, and C.L. Hofacre. \u201cBacteriophage therapy for control of necrotic enteritis of broiler chickens experimentally infected with Clostridium perfringens.\u201d <em>Avian Diseases <\/em>54 no. 1 (2010): 33-40. <a href=\"https:\/\/doi.org\/10.1637\/8953-060509-Reg.1\">https:\/\/doi.org\/10.1637\/8953-060509-Reg.1<\/a><\/p>\n<p>Mitsch, P., K. Zitterl-Eglseer, B. K\u00f6hler, C. Gabler, R. Losa, and I. Zimpernik. \u201cThe Effect of Two Different Blends of Essential Oil Components on the Proliferation of Clostridium perfringens in the Intestines of Broiler Chickens.\u201d <em>Poultry Science <\/em>83 (2004):669\u2013675. <a href=\"https:\/\/doi.org\/10.1093\/ps\/83.4.669\">https:\/\/doi.org\/10.1093\/ps\/83.4.669<\/a><\/p>\n<p>Mitchell, A. \u201cChoosing the right coccidiosis vaccine for layer and breeder chickens.\u201d <em>The Poultry Site <\/em>March 21 (2017). <a href=\"https:\/\/thepoultrysite.com\/articles\/choosing-the-right-coccidiosis-vaccine-for-layer-and-breeder-chickens\">https:\/\/thepoultrysite.com\/articles\/choosing-the-right-coccidiosis-vaccine-for-layer-and-breeder-chickens<\/a><\/p>\n<p>Olkowski, A.A., C. Wojnarowicz, M. Chirino-Trejo, B. Laarveld, and G. Sawicki. \u201cSub-clinical necrotic enteritis in broiler chickens: Novel etiological consideration based on ultra-structural and molecular changes in the intestinal tissue.\u201d <em>Veterinary Science<\/em> 85 (2008): 543\u2013553. <a href=\"https:\/\/doi.org\/10.1016\/j.rvsc.2008.02.007\">https:\/\/doi.org\/10.1016\/j.rvsc.2008.02.007<\/a><\/p>\n<p>Pan, D. and Z. Yu. \u201cIntestinal microbiome of poultry and its interaction with host and diet.\u201d <em>Gut Microbes <\/em>5 no. 1 (2014): 108\u2013119. <a href=\"https:\/\/dx.doi.org\/10.4161\/gmic.26945\">https:\/\/dx.doi.org\/10.4161\/gmic.26945<\/a><\/p>\n<p>Porter, R., Jr. \u201cBacterial enteritides of poultry.\u201d <em>Poult. <\/em><em>Sci.<\/em> 77 (1998):1159\u20131165 <a href=\"https:\/\/doi.org\/10.1093\/ps\/77.8.1159\">https:\/\/doi.org\/10.1093\/ps\/77.8.1159<\/a><\/p>\n<p>Robert Koch Institut. \u201cGrundwissen Antibiotikaresistenz\u201c. <a href=\"https:\/\/www.rki.de\/DE\/Content\/Infekt\/Antibiotikaresistenz\/Grundwissen\/Grundwissen_inhalt.html#:~:text=Wenn%20ein%20neues%20Antibiotikum%20auf,%C3%BCberleben%20und%20vermehren%20sich%20weiter\">https:\/\/www.rki.de\/DE\/Content\/Infekt\/Antibiotikaresistenz\/Grundwissen\/Grundwissen_inhalt.html#:~:text=Wenn%20ein%20neues%20Antibiotikum%20auf,%C3%BCberleben%20und%20vermehren%20sich%20weiter<\/a>.<\/p>\n<p>Rougi\u00e8re, N. and B. Carr\u00e9. \u201cComparison of gastrointestinal transit times between chickens from D + and D- genetic lines selected for divergent digestion efficiency.\u201d <em>Animal <\/em>4 no. 11 (2010): 1861-1872. <a href=\"https:\/\/doi.org\/10.1017\/S1751731110001266\">https:\/\/doi.org\/10.1017\/S1751731110001266<\/a><\/p>\n<p>Santos, F.B.O., B.W. Sheldon, A.A. Santos Jr., and P.R. Ferket. \u201dInfluence of housing system, grain type, and particle size on Salmonella colonization and shedding of broilers fed triticale or corn-soybean meal diets.\u201d <em>Poultry Science<\/em> 87 (2008): 405-420. <a href=\"https:\/\/dx.doi.org\/10.3382\/ps.2006-00417\">https:\/\/dx.doi.org\/10.3382\/ps.2006-00417<\/a><\/p>\n<p>Schiavone, A. , K. Guo, S. Tassone, L .Gasco, E. Hernandez, R. Denti, and I. Zoccarato. \u201cEffects of a Natural Extract of Chestnut Wood on Digestibility, Performance Traits, and Nitrogen Balance of Broiler Chicks.\u201d\u00a0 <em>Poult Sci. <\/em>87 no. 3 (2008): 521-527. <a href=\"https:\/\/doi.org\/10.3382\/ps.2007-00113\">https:\/\/doi.org\/10.3382\/ps.2007-00113<\/a><\/p>\n<p>Shivaramaiah, S., R. E. Wolfenden, J. R. Barta, M. J. Morgan, A. D. Wolfenden, B. M. Hargis, and G. T\u00e9llez. \u201eThe role of an early Salmonella typhimurium infection as a predisposing factor for necrotic enteritis in a laboratory challenge model.\u201d <em>Avian Diseases <\/em>55 (2011): 319-323. <a href=\"https:\/\/doi.org\/10.1637\/9604-112910-ResNote.1\">https:\/\/doi.org\/10.1637\/9604-112910-ResNote.1<\/a><\/p>\n<p>Singh, Y., V. Ravindran, T.J. Wester, A.L. Molan, and G. Ravindran. \u201c Influence of feeding coarse corn on performance, nutrient utilization, digestive tract measurements, carcass characteristics, and cecal microflora counts of broilers.\u201d <em>Poultry\u00a0 Science<\/em> 93 (2014): 607\u2013616. <a href=\"https:\/\/dx.doi.org\/10.3382\/ps.2013-03542\">https:\/\/dx.doi.org\/10.3382\/ps.2013-03542<\/a><\/p>\n<p>Skrivanova, E., M. Marounek, V. Benda, and P. Brezina. \u201cSusceptibility of Escherichia coli, Salmonella sp. and Clostridium perfringens to organic acids and monolaurin.\u201d <em>Veterinarni Medicina <\/em>51 no. 3 (2006): 81\u201388. <a href=\"https:\/\/doi.org\/10.17221\/5524-VETMED\">https:\/\/doi.org\/10.17221\/5524-VETMED<\/a><\/p>\n<p>Songer, J.G. \u201cClostridial Enteric Diseases of Domestic Animals.\u201d <em>Clinical Microbiology Reviews <\/em>9 no. 2 (1996): 216-234. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC172891\/pdf\/090216.pdf\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC172891\/pdf\/090216.pdf<\/a><\/p>\n<p>Stanley D., Wu S.-B., Rodgers N., Swick R.A., and Moore R.J. \u201cDifferential Responses of Cecal Microbiota to Fishmeal, Eimeria and Clostridium perfringens in a Necrotic Enteritis Challenge Model in Chickens.\u201d <em>PLoS ONE<\/em> 9 no. 8 (2014): e104739. <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0104739\">https:\/\/doi.org\/10.1371\/journal.pone.0104739<\/a><\/p>\n<p>Tan, L., D. Rong, Y. Yang, and B. Zhang. \u201cEffect of Oxidized Soybean Oils on Oxidative Status and Intestinal Barrier Function in Broiler Chickens.\u201d <em>Brazilian Journal of Poultry Science<\/em> 18 no. 2 (2018): 333-342. <a href=\"http:\/\/dx.doi.org\/10.1590\/1806-9061-2017-0610\">http:\/\/dx.doi.org\/10.1590\/1806-9061-2017-0610<\/a><\/p>\n<p>Tan, L., D. Rong, Y. Yang, and B. Zhang. \u201cThe Effect of Oxidized Fish Oils on Growth Performance, Oxidative Status, and Intestinal Barrier Function in Broiler Chickens.\u201d <em>J. Appl. Poult. Res.<\/em> 28 (2019): 31-41. <a href=\"http:\/\/dx.doi.org\/10.3382\/japr\/pfy013\">http:\/\/dx.doi.org\/10.3382\/japr\/pfy013<\/a><\/p>\n<p>ThePoultrySite. \u201cNecrotic Enteritis. Disease Guide\u201d. <a href=\"https:\/\/thepoultrysite.com\/disease-guide\/necrotic-enteritis\">https:\/\/thepoultrysite.com\/disease-guide\/necrotic-enteritis<\/a><\/p>\n<p>Timbermont L., A. Lanckriet, J. Dewulf, N. Nollet, K. Schwarzer, F. Haesebrouck, R. Ducatelle, and F. Van Immerseel. \u201cControl of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils.\u201d <em>Avian Pathol. <\/em>39 no. 2 (2010): 117-21. <a href=\"https:\/\/doi.org\/10.1080\/03079451003610586\">https:\/\/doi.org\/10.1080\/03079451003610586<\/a><\/p>\n<p>Tsiouris, V. \u201cPoultry management: a useful tool for the control of necrotic enteritis in poultry.\u201d <em>Avian Pathol.<\/em> 45 no. 3 (2016):323-325. <a href=\"https:\/\/doi.org\/10.1080\/03079457.2016.1154502\">https:\/\/doi.org\/10.1080\/03079457.2016.1154502<\/a><\/p>\n<p>Van der Most, P.J., B. de Jong, H.K. Parmentier and S. Verhulst. \u201cTrade-off between growth and immune function: a meta-analysis of selection experiments.\u201d <em>Functional Ecology <\/em>25 (2011): 74-80. https:\/\/doi.org\/0.1111\/j.1365-2435.2010.01800.x<\/p>\n<p>Van der Sluis, W. \u201cClostridial enteritis is an often underestimated problem.\u201d <em>Worlds Poult. Sci. J. <\/em>16 (2000):42\u201343.<\/p>\n<p>Van der Suis, W. \u201cNecrotic enteritis kills birds and profits.\u201d <em>Poultry World <\/em>Apr5 (2013). <a href=\"https:\/\/www.poultryworld.net\/Health\/Articles\/2013\/4\/necrotic-enteritis-kills-birds-and-profits-1220877W\/\">https:\/\/www.poultryworld.net\/Health\/Articles\/2013\/4\/necrotic-enteritis-kills-birds-and-profits-1220877W\/<\/a><\/p>\n<p>Van Immerseel, F., J. De Buck, F. Pasmans, G. Huyghebaert, F. Haesebrouck, and R. Ducatelle. \u201cClostridium perfringens in poultry: an emerging threat of animal and public health.\u201d <em>Avian Pathology <\/em>33 (2004): 537-549. <a href=\"https:\/\/doi.org\/10.1080\/03079450400013162\">https:\/\/doi.org\/10.1080\/03079450400013162<\/a><\/p>\n<p>Van Immerseel, F., J.I. Rood, R.J. Moore, and R.W. Titball. \u201cRethinking our understanding of the pathogenesis of necrotic enteritis in chickens.\u201d <em>Trends in Microbiology <\/em>17 no. 1 (2008):32-36. <a href=\"https:\/\/doi.org\/10.1016\/j.tim.2008.09.005\">https:\/\/doi.org\/10.1016\/j.tim.2008.09.005<\/a><\/p>\n<p>Wade, B., A. Keyburn. \u201cThe true cost of necrotic enteritis.\u201d <em>World Poultry <\/em>31 no. 7 (2015): 16\u201317. <a href=\"https:\/\/www.poultryworld.net\/Meat\/Articles\/2015\/10\/The-true-cost-of-necrotic-enteritis-2699819W\/\">https:\/\/www.poultryworld.net\/Meat\/Articles\/2015\/10\/The-true-cost-of-necrotic-enteritis-2699819W\/<\/a><\/p>\n<p>Wade, B., A.L. Keyburn, T. Seemann, J.I. Rood, and R.J. Moore. \u201cBinding of Clostridium perfringens to collagen correlates with the ability to cause necrotic enteritis in chickens.\u201d <em>Veterinary Microbiology <\/em>180 no. 3\u20134 (2015): 299-303. <a href=\"https:\/\/doi.org\/10.1016\/j.vetmic.2015.09.019\">https:\/\/doi.org\/10.1016\/j.vetmic.2015.09.019<\/a><\/p>\n<p>Williams, R.B. \u201cIntercurrent coccidiosis and necrotic enteritis of chickens: rational, integrated disease management by maintenance of gut integrity.\u201d <em>Avian Pathology<\/em> 34 no. 3 (2005):159-180. <a href=\"https:\/\/doi.org\/10.1080\/03079450500112195\">https:\/\/doi.org\/10.1080\/03079450500112195<\/a><\/p>\n<p>Yang , C.M., G.T. Cao, P.R. Ferket, T.T. Liu, L. Zhou, L. Zhang, Y.P. Xiao, and A. G. Chen. \u201c Effects of probiotic, Clostridium butyricum, on growth performance, immune function, and cecal microflora in broiler chickens.\u201d<em> Poultry Science <\/em>91 (2012): 2121\u20132129. <a href=\"https:\/\/dx.doi.org\/10.3382\/ps.2011-02131\">https:\/\/dx.doi.org\/10.3382\/ps.2011-02131<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>by Inge Heinzl, Marisabel Caballero, Ajay Bhoyar, EW Nutrition \u3042\u306a\u305f\u306e\u904b\u55b6\u304b\u3089\u58ca\u6b7b\u6027\u8178\u708e\u3092\u6392\u9664\u3059\u308b\u306b\u306f\u3001\u305d\u308c\u304c\u4f55\u3067\u3042\u308b\u304b\u3001\u4e88\u9632\u65b9\u6cd5\u3001\u304a\u3088\u3073\u5bb6\u79bd\u751f\u7523\u3078\u306e\u5f71\u97ff\u3092\u8efd\u6e1b\u3059\u308b\u65b9\u6cd5\u306b\u3064\u3044\u3066\u5341\u5206\u306b\u7406\u89e3\u3059\u308b\u3053\u3068\u304b\u3089\u59cb\u307e\u308a\u307e\u3059\u3002 \u58ca\u6b7b\u6027\u8178\u708e\u306f\u3001\u5c0f\u8178\u3067Clostridium perfringens A\u578b\u304a\u3088\u3073C\u578b\u306e\u904e\u5270\u5897\u6b96\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u5bb6\u79bd\u75be\u60a3\u3067\u3059\u3002C.perfringens \u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u6bd2\u7d20\u306f\u3001\u8178\u58c1\u306b\u640d\u50b7\u3092\u4e0e\u3048\u307e\u3059\u3002\u4e00\u822c\u306b\u30012\u301c6\u9031\u9f62\u306e\u30d6\u30ed\u30a4\u30e9\u30fc\u3067\u8d77\u3053\u308a\u307e\u3059\u3002\u7121\u75c7\u72b6\u578b\u3067\u306f\u3001\u6d88\u5316\u7ba1\u306e\u969c\u5bb3\u3092\u7279\u5fb4\u3068\u3057\u307e\u3059\u3002\u81e8\u5e8a\u5f62\u614b\u306f\u3001\u975e\u5e38\u306b\u77ed\u6642\u9593\u3067\u6df1\u523b\u306a\u554f\u984c\u3092\u3082\u305f\u3089\u3057\u3001\u540c\u7fa4\u3067\u306e\u6b7b\u4ea1\u7387\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002 \u58ca\u6b7b\u6027\u8178\u708e\u306f\u3001\u4e16\u754c\u7684\u306a\u5bb6\u79bd\u751f\u7523\u306b\u304a\u3044\u3066\u5e74\u959360\u5104\u30c9\u30eb\u306e\u640d\u5931\u306e\u539f\u56e0\u3067\u3001\u3053\u306e\u75be\u60a3\u306f\u5897\u52a0\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306e1\u3064\u306f\u3001\u52d5\u7269\u751f\u7523\u306b\u304a\u3044\u3066\u6297\u751f\u7269\u8cea\u306e\u81ea\u4e3b\u7684\u307e\u305f\u306f\u6cd5\u7684\u7fa9\u52d9\u306b\u3088\u308b\u524a\u6e1b\u306b\u3088\u308b\u305f\u3081\u3067\u3059\u3002\u3053\u306e\u50be\u5411\u306f\u3001\u6297\u83cc\u5264\u8010\u6027\u306e\u5897\u52a0\u304a\u3088\u3073\u6d88\u8cbb\u8005\u306e\u9700\u8981\u306b\u3088\u3063\u3066\u63a8\u9032\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3082\u3046\u4e00\u3064\u306e\u7406\u7531\u306f\u3001\u30b3\u30af\u30b7\u30b8\u30a2\u306e\u5897\u6b96\u306b\u52a0\u3048\u3066\u3001\u30af\u30ed\u30b9\u30c8\u30ea\u30b8\u30a6\u30e0\u306b\u5bfe\u3057\u3066\u3082\u6709\u52b9\u6027\u3092\u793a\u3059\u30a4\u30aa\u30ce\u30d5\u30a9\u30a2\u306e\u4f7f\u7528\u6e1b\u5c11\u3067\u3059\u3002\u6297\u30b3\u30af\u30b7\u30b8\u30a6\u30e0\u751f\u30ef\u30af\u30c1\u30f3\u3092\u4f7f\u7528\u3059\u308b\u5834\u5408\u3001\u3053\u308c\u3089\u306e\u30a4\u30aa\u30ce\u30d5\u30a9\u30a2\u306e\u4f7f\u7528\u304c\u3067\u304d\u305a\u3001\u30af\u30ed\u30b9\u30c8\u30ea\u30b8\u30a6\u30e0\/\u58ca\u6b7b\u6027\u8178\u708e\u304c\u5897\u52a0\u3057\u307e\u3059 (Williams, 2005)\u3002 \u3053\u308c\u306f\u3059\u3079\u3066\u306e\u5bb6\u79bd\u3067\u5e83\u7bc4\u306a\u554f\u984c\u3067\u3059\u304c\u3001\u7279\u306b\u30d6\u30ed\u30a4\u30e9\u30fc\u306b\u3068\u3063\u3066\u3001\u58ca\u6b7b\u6027\u8178\u708e\u304a\u3088\u3073\u30b3\u30af\u30b7\u30b8\u30a6\u30e0\u75c7\u306f\u6700\u3082\u91cd\u8981\u306a\u5065\u5eb7\u554f\u984c\u3067\u3059\u3002 \u58ca\u6b7b\u6027\u8178\u708e(NE)\u306e\u75c7\u72b6\u304a\u3088\u3073\u7121\u75c7\u72b6\u75be\u60a3 \u75c7\u72b6 \u6025\u6027\u306e\u9ed2\u3063\u307d\u3044\u4e0b\u75e2\u306b\u3088\u3063\u3066\u6fe1\u308c\u305f\u6577\u304d\u85c1\u3092\u767a\u898b\u3057\u3001\u6700\u521d\u306e\u81e8\u5e8a\u5fb4\u5019\u304c\u73fe\u308c\u305f\u5f8c\u3001\u7a81\u71361\u65e5\u3042\u305f\u308a\u6700\u59271\uff05\u306e\u96c6\u56e3\u6b7b\u4ea1\u7387\u306e\u4e0a\u6607\u3092\u7279\u5fb4\u3068\u3057\u307e\u3059\uff08Ducatelle, 2010\uff09\u3002\u6b7b\u4ea1\u7387\u306f\u6642\u300550\uff05\u307e\u3067\u4e0a\u6607\u3057\u307e\u3059\uff08Van der Sluis, 2013\uff09\u3002\u9d8f\u306f\u6c5a\u308c\u305f\u7fbd\u6bdb\u3001\u7121\u6c17\u529b\u3001\u98df\u6b32\u4e0d\u632f\u304c\u898b\u3089\u308c\u307e\u3059\u3002 \u5178\u578b\u7684\u306a\u58ca\u6b7b\u306f\u3001\u7c98\u819c\u8868\u9762\u304c\u8352\u308c\u3001\u75c5\u5909\u3001\u304a\u3088\u3073\u8336\u8272\u3063\u307d\u3044\uff08\u30b8\u30d5\u30c6\u30ea\u30a2\u69d8\uff09\u7591\u4f3c\u819c\u3092\u6709\u3059\u308b\u81a8\u3089\u3093\u3060\u5c0f\u8178\u3092\u793a\u3057\u307e\u3059\u3002\u6b7b\u5f8c\u306e\u691c\u67fb\u3067\u306f\u3001\u5927\u91cf\u306e\u6c34\u3063\u307d\u3044\u8336\u8272\u3067\u3001\u8840\u304c\u6df7\u3056\u3063\u305f\u6db2\u4f53\u3067\u3001\u60aa\u81ed\u304c\u3042\u308a\u307e\u3059\u3002\u809d\u81d3\u306f\u9ed2\u304f\u816b\u308c\u3066\u5805\u304f\u306a\u308a\u3001\u80c6\u56a2\u306f\u81a8\u6e80\u3057\u307e\u3059 (Hofacre, 2018)\u3002 \u904e\u6025\u6027\u58ca\u6b7b\u6027\u8178\u708e\u306e\u5834\u5408\u3001\u9d8f\u306f\u521d\u671f\u75c7\u72b6\u3092\u793a\u3055\u305a\u306b\u6b7b\u4ea1\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002 \u7121\u75c7\u72b6\u75be\u60a3 \u9d8f\u304c\u7121\u75c7\u72b6\u306a\u306e\u306b\u82e6\u3057\u3080\u5834\u5408\u3001\u8178\u7c98\u819c\u306e\u6162\u6027\u7684\u306a\u640d\u50b7\u3068\u5c0f\u8178\u5185\u306e\u7c98\u6db2\u91cf\u306e\u5897\u52a0\u306f\u3001\u6804\u990a\u7d20\u306e\u6d88\u5316\u3068\u5438\u53ce\u306e\u969c\u5bb3\u306b\u3064\u306a\u304c\u308a\u3001\u6210\u9577\u304c\u60aa\u304f\u306a\u308a\u307e\u3059\u3002 \u52a3\u5316\u3057\u305f\u98fc\u6599\u3078\u306e\u5909\u63db\u3068\u305d\u306e\u7d50\u679c\u751f\u3058\u308b\u6210\u9577\u306e\u4f4e\u4e0b\u306f\u300135\u65e5\u9f62\u9803\u306b\u9855\u8457\u306b\u306a\u308a\u307e\u3059\u3002\u98fc\u6599\u304c\u30d6\u30ed\u30a4\u30e9\u30fc\u9d8f\u306e\u751f\u7523\u30b3\u30b9\u30c8\u306e\u7d04 65\uff5e75%\u5bc4\u4e0e\u3059\u308b\u305f\u3081\u3001\u98fc\u6599\u5909\u63db\u304c\u4e0d\u5341\u5206\u3067\u3042\u308b\u3068\u3001\u751f\u7523\u30b3\u30b9\u30c8\u304c\u5897\u52a0\u3057\u3001\u53ce\u76ca\u6027\u306b\u5927\u304d\u304f\u5f71\u97ff\u3057\u307e\u3059\u3002\u3057\u3070\u3057\u3070\u3001\u660e\u78ba\u306a\u75c7\u72b6\u306e\u6b20\u5982\u306e\u305f\u3081\u306b\u3001\u3053\u306e\u7121\u75c7\u72b6\u75be\u60a3\u306f\u672a\u6cbb\u7642\u306e\u307e\u307e\u3067\u3042\u308a\u3001\u751f\u7523\u52b9\u7387\u306b\u6052\u4e45\u7684\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002 &nbsp; \u75c5\u539f\u4f53 \u58ca\u6b7b\u306e\u539f\u56e0\u306f\u3001\u30b0\u30e9\u30e0\u967d\u6027\u5acc\u6c17\u6027\u7d30\u83cc\u306eClostridium perfringens A\u578b\u306e\u7279\u5b9a\u306e\u682a\u3068\u3001\u4e00\u90e8\u306eC\u578b\u682a\u3067\u3059\uff08Keyburn, 2008\uff09\u3002 \u30af\u30ed\u30b9\u30c8\u30ea\u30b8\u30a6\u30e0\u306f\u3001\u4e3b\u306b\u6709\u6a5f\u7269\u8cea\u304c\u5206\u89e3\u3055\u308c\u308b\u571f\u58cc\u3001\u4e0b\u6c34\u3001\u52d5\u7269\u3084\u30d2\u30c8\u306e\u80c3\u8178\u7ba1\u3067\u5897\u6b96\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u7d30\u83cc\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u6d88\u6bd2\u5264\u3068\u540c\u69d8\u306b\u3001\u74b0\u5883\u3078\u306e\u5f71\u97ff\uff08\u71b1\u3001\u7167\u5c04\u3001\u6392\u9664\uff09\u306b\u3082\u975e\u5e38\u306b\u8010\u6027\u304c\u3042\u308a\u3001\u6570\u5e74\u9593\u751f\u5b58\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u9069\u5207\u306a\u6761\u4ef6\u4e0b\u3067\u306f\u3001 C.perfringens\u306e\u82bd\u80de\u306f\u98fc\u6599\u3084\u6577\u304d\u85c1\u3067\u5897\u6b96\u3059\u308b\u3053\u3068\u3055\u3048\u3042\u308a\u307e\u3059\u3002 C.perfringens\u306f\u3001\u9d8f\u306e\u8178\u306e\u5e38\u5728\u83cc\u3067\u3059\u3002\u5065\u5eb7\u306a\u9d8f\u3067\u306f\u3001\u6d88\u5316\u7ba1\u3067102\uff5e104 CFU\/g\u3042\u308a\u591a\u7a2e\u591a\u69d8\u306a\u7d30\u83cc\u306e\u6df7\u5408\u7269\u4e2d\u306b\u751f\u5b58\u3057\u3066\u3044\u307e\u3059 (McDevittet, 2006)\u3002\u3053\u306e\u75be\u60a3\u306f\u3001\u901a\u5e38\u3001\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u4f4e\u514d\u75ab\u3001\u304a\u3088\u3073\u8178\u5185\u7d30\u83cc\u53e2\u306e\u4e0d\u5747\u8861\u306a\u3069\u306e\u8981\u56e0\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u308a\u5c0f\u8178\u3067\u6025\u5897\u3057\u305f\u3068\u304d\u306b\u767a\u75c7\u3057\u307e\u3059\u3002\u305d\u306e\u5f8c\u3001\u83cc\u6570\u306f\u6d88\u5316\u7ba1\u3067107\uff5e109 CFU\/g\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002\uff08Dahiya, 2005\uff09 \u58ca\u6b7b\u6027\u8178\u708eB\u6bd2\u7d20(NetB)\uff1b\u58ca\u6b7b\u6027\u8178\u708e(NE)\u306b\u3068\u3063\u3066\u306e\u91cd\u8981\u306a\u75c5\u539f\u6027\u56e0\u5b50 \u5bbf\u4e3b\u3067\u7acb\u8a3c\u3059\u308b\u305f\u3081\u306b\u3001 Clostridium \u5c5e\u304a\u3088\u3073\u4ed6\u306e\u75c5\u539f\u4f53\u306f\u3001\u75c5\u539f\u6027\u56e0\u5b50\u306b\u4f9d\u5b58\u3057\u307e\u3059\uff08\u30a4\u30f3\u30d5\u30a9\u30dc\u30c3\u30af\u30b9\u3092\u53c2\u7167\uff09\u3002\u3053\u308c\u3089\u306e\u75c5\u539f\u6027\u56e0\u5b50\u306b\u306f\u3001\u4f8b\u3048\u3070\u3001\u5bbf\u4e3b\u306e\u514d\u75ab\u7cfb\u3078\u306e\u4ed8\u7740\u3001\u56de\u907f\u307e\u305f\u306f\u6291\u5236\u306e\u305f\u3081\u306e\u300c\u624b\u6bb5\u300d\u3001\u6804\u990a\u7d20\u3092\u5f97\u308b\u305f\u3081\u306e\u300c\u624b\u6bb5\u300d\u3001\u8178\u7d30\u80de\u3078\u306e\u4fb5\u5165\u306e\u305f\u3081\u306e\u300c\u624b\u6bb5\u300d\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u9577\u5e74\u306b\u308f\u305f\u308a\u3001C.perfringens \u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u03b1\u6bd2\u7d20\u306f\u3001\u3053\u306e\u75be\u60a3\u306e\u767a\u75c7\u304a\u3088\u3073\u4e3b\u8981\u306a\u75c5\u539f\u6027\u56e0\u5b50\u306b\u95a2\u4e0e\u3059\u308b\u3068\u4eee\u5b9a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u30022008\u5e74Keyburn\u306f\u3001\u03b1\u30c8\u30ad\u30b7\u30f3\u3092\u7523\u751f\u3057\u306a\u3044\u304c\u3001\u58ca\u6b7b\u6027\u8178\u708e\u3092\u5f15\u304d\u8d77\u3053\u3059 C.perfringens \u5909\u7570\u682a\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u5225\u306e\u91cd\u8981\u306a\u75c5\u539f\u6027\u56e0\u5b50\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002 \u305d\u308c\u3067\u3001\u58ca\u6b7b\u6027\u8178\u708e\u306b\u7f79\u60a3\u3057\u3066\u3044\u308b\u9d8f\u306b\u306e\u307f\u5b58\u5728\u3059\u308b\u5225\u306e\u6bd2\u7d20\u304c\u540c\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002C.perfringens\u58ca\u6b7b\u6027\u8178\u708eB\u6bd2\u7d20\uff08NetB\uff09\u3067\u3059\u3002NetB\u306f\u5b54\u5f62\u6210\u6bd2\u7d20\u3067\u3059\u3002\u5b54\u5f62\u6210\u6bd2\u7d20\u306f\u3001\u901a\u5e38\u75c5\u539f\u83cc\u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u5916\u6bd2\u7d20\u3067\u3001\u4ed6\u306e\u5fae\u751f\u7269\u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6bd2\u7d20\u306f\u3001\u8178\u58c1\u7d30\u80de\u819c\u306e\u9ad8\u6f54\u3092\u7834\u58ca\u3057\u307e\u3059\u3002\u6f0f\u308c\u305f\u7d30\u80de\u306e\u5185\u5bb9\u7269\u306f\u3001\u7d30\u83cc\u306e\u305f\u3081\u306e\u6804\u990a\u7d20\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u514d\u75ab\u7d30\u80de\u304c\u7834\u58ca\u3055\u308c\u308b\u3068\u3001\u514d\u75ab\u53cd\u5fdc\u304c\u90e8\u5206\u7684\u306b\u5f71\u97ff\u3092\u53d7\u3051\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08Los,&#8230;<\/p>\n","protected":false},"author":7,"featured_media":55545,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[155],"tags":[],"class_list":["post-62141","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-155"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v28.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981 - EW Nutrition<\/title>\n<meta name=\"description\" content=\"Necrotic enteritis: what it is, how to prevent it, and how to mitigate its effects on your poultry production.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ew-nutrition.com\/ja\/\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981\" \/>\n<meta property=\"og:description\" content=\"Necrotic enteritis: what it is, how to prevent it, and how to mitigate its effects on your poultry production.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ew-nutrition.com\/ja\/\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981\/\" \/>\n<meta property=\"og:site_name\" content=\"EW Nutrition\" \/>\n<meta property=\"article:published_time\" content=\"2020-12-14T12:28:07+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-27T07:05:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/260138_2575_sxc.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"737\" \/>\n\t<meta property=\"og:image:height\" content=\"491\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ilinca Anghelescu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@EWNutritionGmbH\" \/>\n<meta name=\"twitter:site\" content=\"@EWNutritionGmbH\" \/>\n<meta name=\"twitter:label1\" content=\"\u57f7\u7b46\u8005\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ilinca Anghelescu\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593\" \/>\n\t<meta name=\"twitter:data2\" content=\"11 minutes\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981 - EW Nutrition","description":"Necrotic enteritis: what it is, how to prevent it, and how to mitigate its effects on your poultry production.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ew-nutrition.com\/ja\/\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981\/","og_locale":"ja_JP","og_type":"article","og_title":"\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981","og_description":"Necrotic enteritis: what it is, how to prevent it, and how to mitigate its effects on your poultry production.","og_url":"https:\/\/ew-nutrition.com\/ja\/\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981\/","og_site_name":"EW Nutrition","article_published_time":"2020-12-14T12:28:07+00:00","article_modified_time":"2023-03-27T07:05:41+00:00","og_image":[{"width":737,"height":491,"url":"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/260138_2575_sxc.jpg","type":"image\/jpeg"}],"author":"Ilinca Anghelescu","twitter_card":"summary_large_image","twitter_creator":"@EWNutritionGmbH","twitter_site":"@EWNutritionGmbH","twitter_misc":{"\u57f7\u7b46\u8005":"Ilinca Anghelescu","\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593":"11 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/#article","isPartOf":{"@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/"},"author":{"name":"Ilinca Anghelescu","@id":"https:\/\/ew-nutrition.com\/#\/schema\/person\/6903b5a154e6729efcce4961da6555e7"},"headline":"\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981","datePublished":"2020-12-14T12:28:07+00:00","dateModified":"2023-03-27T07:05:41+00:00","mainEntityOfPage":{"@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/"},"wordCount":2302,"publisher":{"@id":"https:\/\/ew-nutrition.com\/#organization"},"image":{"@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/#primaryimage"},"thumbnailUrl":"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/260138_2575_sxc.jpg","articleSection":["\u30ab\u30c6\u30b4\u30ea\u30fc\u306a\u3057"],"inLanguage":"ja"},{"@type":"WebPage","@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/","url":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/","name":"\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981 - EW Nutrition","isPartOf":{"@id":"https:\/\/ew-nutrition.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/#primaryimage"},"image":{"@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/#primaryimage"},"thumbnailUrl":"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/260138_2575_sxc.jpg","datePublished":"2020-12-14T12:28:07+00:00","dateModified":"2023-03-27T07:05:41+00:00","description":"Necrotic enteritis: what it is, how to prevent it, and how to mitigate its effects on your poultry production.","breadcrumb":{"@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/#breadcrumb"},"inLanguage":"ja","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/"]}]},{"@type":"ImageObject","inLanguage":"ja","@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/#primaryimage","url":"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/260138_2575_sxc.jpg","contentUrl":"https:\/\/ew-nutrition.com\/wp-content\/uploads\/articles\/260138_2575_sxc.jpg","width":737,"height":491,"caption":"260138 2575 sxc"},{"@type":"BreadcrumbList","@id":"https:\/\/ew-nutrition.com\/ja\/%e5%a3%8a%e6%ad%bb%e6%80%a7%e8%85%b8%e7%82%8e%ef%bc%9a%e6%a6%82%e8%a6%81\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/ew-nutrition.com\/ja\/"},{"@type":"ListItem","position":2,"name":"\u58ca\u6b7b\u6027\u8178\u708e\uff1a\u6982\u8981"}]},{"@type":"WebSite","@id":"https:\/\/ew-nutrition.com\/#website","url":"https:\/\/ew-nutrition.com\/","name":"EW Nutrition","description":"Functional Innovations backed by Science","publisher":{"@id":"https:\/\/ew-nutrition.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ew-nutrition.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ja"},{"@type":"Organization","@id":"https:\/\/ew-nutrition.com\/#organization","name":"EW Nutrition GmbH","url":"https:\/\/ew-nutrition.com\/","logo":{"@type":"ImageObject","inLanguage":"ja","@id":"https:\/\/ew-nutrition.com\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"EW Nutrition GmbH"},"image":{"@id":"https:\/\/ew-nutrition.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/x.com\/EWNutritionGmbH","https:\/\/www.instagram.com\/ewnutrition\/","https:\/\/www.linkedin.com\/company\/ew-nutrition","https:\/\/www.youtube.com\/channel\/UCIvcb19uSOJXrUecTY8n_dA"]},{"@type":"Person","@id":"https:\/\/ew-nutrition.com\/#\/schema\/person\/6903b5a154e6729efcce4961da6555e7","name":"Ilinca Anghelescu","url":"https:\/\/ew-nutrition.com\/ja\/author\/ianghelescu\/"}]}},"_links":{"self":[{"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/posts\/62141","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/comments?post=62141"}],"version-history":[{"count":0,"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/posts\/62141\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/media\/55545"}],"wp:attachment":[{"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/media?parent=62141"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/categories?post=62141"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ew-nutrition.com\/ja\/wp-json\/wp\/v2\/tags?post=62141"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}